Chronic colitis

As regards respiratory apparatus, intoxication is manifested in the development of catarrh of upper air passages and bronchitis with dyspnea, but more often damage is limited to impaired vital capacity of lungs. Affection of gastrointestinal tract is manifested in gastritis and chronic colitis. 

Arthritis, chronic colitis, peptic ulcer, gastritis, enteritis, influenza, liver diseases, hypothyroidism, chronic nephritis, myocardial infarction, myocarditis, severe blood loss, trauma, severe dehydration and allergies. 

Pao Sheng Jiang is bitter and warm, and enters the Middle-Jiao and the Spleen meridian. It particularly warms the Middle-Jiao and stops bleeding caused by Spleen-Yang deficiency, such as in peptic ulcer, chronic colitis and dysentery. It can also be selected as deputy in formulas that warm the Middle-Jiao. 

Zao Xi Tu is warm and astringent, and enters the Spleen and Stomach meridians. It warms the interior and stops bleeding in both the Middle- and Lower-Jiao, such as bleeding from the stomach, intestines and uterus. Moreover, it binds up the intestines and stops diarrhea. It is more suitable for conditions of Spleen-Yang deficiency, such as chronic colitis, which manifests as abdominal pain and cramp, diarrhea, intestinal hemorrhage, cold hands and feet, and a pale complexion. 

In 30 patients aged 18 8 years with chronic colitis, characterized by vague lower abdominal pain, rectal bleeding, diarrhea, and palpable tender descending and sigmoid colons, Boswellia serrata (900 mg/day for 6 weeks) produced remission in 14 of 20 patients, and sulfasalazine (3 g/day for 6 weeks) in 4 of 10 patients (4). There were few adverse effects. 

Gupta I, Parihar A, Malhotra P, Gupta S, Ludtke R, Safayhi H, Ammon HP. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001 67(5) 391-5. 

Intestinal alkaline phosphatase has beneficial effects in mouse models of chronic colitis. Infiamm Bowel Dis 17 532-542... 

Indications Cold accumulation interior repletion. Stomach and intestinal spasms, pyelonephritis, kidney stones, gallstones, pancreatitis, intestinal colic, hernia pain, sciatica, intercostal neuralgia, migraines, chronic colitis, and chronic pelvic inflammation... 

Indications Spleen/kidney vacuity cold, prolonged diarrhea and dysentery. Chronic colitis, chronic diarrhea in children, Crohn s disease, ulcerative colitis, chronic dysentery, celiac syndrome, and pancreatic dysfunction... 

Hokari, R. et al.. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis. Free Radic. Biol. Med., 31 (2), 153,2001. 

Jijon HB, Churchill T, Malfair D et al. Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis. Am J Physiol Gastrointest Liver Physiol 2000 279(3) G641-51. 

Ribbons KA, Currie MG, Connor JR et al. The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey. J Pharmacol Exp Ther 1997 280 1008-15. 

Niacin requirements are also affected by diseases or conditions interfering with niacin absorption and/or processing, such as prolonged diarrhoea, chronic dialysis treatment, chronic colitis (particularly ulcerative colitis), cirrhosis of the liver, tuberculosis of the gastrointestinal tract, malignant carcinoid tumour and chronic alcoholism (Food and Nutrition Board 1998). Substantial individual differences (about 30%) in the conversion efficiency of tryptophan to niacin have been reported (Horwitt et al. 1981). 

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