Start-up Companies

Robert A. Swanson and biochemist Dr Herbert W. Boyer, and the changes in state and federal laws (the 1980 Bayh-Dole Act) paved the way for universities and academicians to participate in fostering business alliances and creating new companies. 

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Mikroreaktorenfur die chemische Synthese, Nachrichten aus der Chemie, May 2000 Chip technology initiates quest for small structures better temperature control on the small scale fast mixing by diffusion several kg productivity per day no novel, but better chemistry perfect control over process parameters corresponding increase in selectivity basic micro-reactor functions selected examples of use micro reactors as routine tools in the laboratory first start-up companies [113],... 

The development of start-up companies in the field of micro-systems technology, including microfluidics, has been reviewed by Wicht et al. [244]. Different types of business models are presented as well as the corresponding growth models. The development of start-ups in Germany in the last 10 years is presented and the product offer is discussed. This is compared with the situation in other European countries. Finally, information on problems and opportimities for the start-ups is provided. 

Le Floch, C., From research to industry start-up companies in microsystems, in Proceedings of the VDE World Microtechnologies Congress, MICRO.tec 2000, pp. 639-643 (25-27 September 2000), VDE Verlag, Berlin, EXPO Hannover. 

Beyond research, powerful trends are already evident in business (Figure 8.10). Not only do a growing number of start-up companies now commercialize products obtained via a nanochemistry approach but also national laboratories, military establishments and very big chemical... 

In one approach for the controlled delivery of a wide range of active ingredients, including viruses, pursued by Finland s start-up company DelSiTech, the technology is based on a Si02 matrix into which the active ingredient is first embedded followed by dissolution and release on contact with body fluids (Figure 2.8). 

Sep Adaptive Learning and Business Niche Discovery Raising Capital For Your Own Start-up Company ... 

During the 1980s and early 1990s, there were little or no official university regulations at most institutions regarding faculty participation in or sitting on boards of start-up companies they founded. Much of the concerns since the middle 1990s arose from... 

On the other hand, small start-up companies focused intensely and entirely on what they were created to do, with the incentive that early and even later employees would be well rewarded if the venture was successful. It was clear to me, in this case, that if the translation from basic and preclinical research to clinical trials were to occur, our best chance was to initiate a company. For the most part, big pharmaceutical houses have stayed clear of allosteric effectors as drugs. We had the enormous advantage that far more is known about hemoglobin as an allosteric protein than any other. 

Having a dedicated start-up company to champion moving a molecule through all the steps to an NDA made the difference as large pharmaceutical companies are less likely to champion a compound from academia. 

We may consider all the operations of a start-up company, or the incremental operations of a project attached to an existing company. Let us consider the example in table 11.6. 

Start up company HT-Ceramics, which has developed a specific (anode supported thin layer electrolyte) SOFC system. The PEM research is carried out by the Paul Scherrer Institute in collaboration with the Federal Institute of Technology Zurich and the University of applied science in Biel. The Paul Scherrer Institute is also researching DMFC systems, while the Federal Institute of Technology Lausanne is involved in research activities for HTcceramics. 

An asset of the Aachen/Jiilich bioorganic synthesis approach is technology transfer, which is testified by no less than five start-up companies. Scale-up requires stable and highly efficient enzymes as well as appropriate reaction technology. The development of membrane reactors has been a key to success. Reaction technology is outlined by C. Wandrey and co-workers in the final article. 

As a start-up company, ChemKit does not have a portfolio of pilot projects at this time. Here the Austrian consulting market offers an attractive niche to allow the company to become established. The viability and profitability of the business idea can be proved by numerous pilot projects, which will serve as a trust-building reference for potential customers. 

A common misconception of pharmaceutical and especially smaller biopharmaceutical companies is that the implementation of a robust QMS is not required in areas other than commercial manufacturing. Small, biotech start-up companies also tend to delay the implementation of well-designed processes until they near the approval stage, focusing the organization instead for product approval or sale. This... 

The demand in the market that had hitherto been unmet in order to maintain price levels was now taken up by Indian start-up companies willing to supply the whole market, even where it could barely break even. High quality, comparably very low-cost generics lowered the price bar to medicine access. Thus, when the HIV/AIDS crisis came to India there was an industry able to prevent the travesty that occurred in Africa. 

Mary L. Good The rationale truly is almost ideological. People don t believe that large companies should be subsidized for research they believe the companies should do anyway. There is also a myth that small start-up companies should get some help. But in terms of the value of results, for example, DARPA does not, should not, and probably never will eliminate large companies. Even the new ATP rules will still let large companies participate, but there was a thought process that said that the American economy was built on start-ups. What people forget is to look at the whole infrastructure. 

Corporate contracts and start-up companies—facilitate cooperation... 

From the university s perspective, these relationships can be very attractive. First, there is the obvious desire to tap some of the economic value of such partnerships. A cycle exists wherein technology is spun out of universities and makes companies successful. In return, corporate donations and royalties come back to the universities. Licensing revenues can be very substantial. In addition, start-up companies can create very wealthy entrepreneurs who are carefully tracked by the university. Eventually the... 

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