Soreness subcutaneous

A pressure sore is a chronic wound that results from continuous pressure on the tissue overlying a bony prominence. This pressure impedes blood flow to the dermis and subcutaneous fat, resulting in tissue damage and necrosis.37,38... 

Stage 2 A stage 2 sore may also be reversible it extends through the dermis to the subcutaneous fat along with extensive undermining. 

Transient mild soreness may occur at the site of IM or subcutaneous injection. Too rapid IV administration may cause temporary faintness or dizziness. 

Immunodeficiency 100-200 mg/kg/mo IV at 0.01-0.04 mL/kg/min to 400 mg/kg/dose max UP 400 mg/kg/dose IV daily x 5 d BMP 500 mg/kg/wk X in renal insuff Caution [C, ] Separate administration of live vaccines by 3 mo Contra IgA deficiency w/ Abs to IgA, severe thrombocytopenia or coagulation disorders Disp Inj SE Associated mostly w/ inf rate GI upset Interactions X Effects OF live virus vaccines EMS May cause anaphylactic Rxn OD Unlikely Immune Globulin, Subcutaneous (Vivaglobin) [Immune Serum] Uses Primary immunodeficiency Action IgG supl Dose 100—200 mg/kg BW subq wkly abd, thighs, upp arms, or lat al hip Caution [C, ] Contra Hx anaphylaxis to immune globulin some IGA deficiency Disp Inj SE Inj site Rxns, HA, GI complaint, fevCT, N, D, rash, sore throat EMS May be self administered at home may cause anaphylactic Rxn OD Unlikely to cause life-threatening Sxs... 

IM, Subcutaneous (10%) Nausea (may occur 30 min after injection, usually diminishes with continued therapy), inflammation at injection site Nasal (12%-i0%) Rhinitis, nasal irritation, redness, sores Occasional... 

Recombinant human IL-11 (oprelvekin) is a polypeptide of 177 amino acids. It differs from natural IL-11 due to lack of glycosylation and the amino-terminal proline residue. Oprelvekin is administered by subcutaneous injection, usually 6-24 h after chemotherapy, at a dose of 25-50 p,g/kg per day. The drug has a half-life of about 7h. It is used to stimulate bone marrow to induce platelet production in nonmyeloid malignancies in patients undergoing chemotherapy. The common side effects of oprelvekin include fluid retention, tachycardia, edema, nausea, vomiting, diarrhea, shortness of breath and mouth sores. Other side effects include rash at the injection site, blurred vision, paresthesias, headache, fever, cough and bone pain. Rarely, CLS may occur. 

A 22-year-old previously healthy man presented with acute sore throat awakening him from sleep (110). He had palpable crepitation due to extensive cervical subcutaneous emphysema. A chest X-ray showed a pneumomediastinum and bilateral apical pneumothoraces. CT scan did not show any underlying lung disease. Bronchoscopy was unremarkable except for a swollen nasal mucosa and acute bronchitis. Bronchoalveolar lavage was normal without evidence of infection. The patient reported repeated cocaine consumption. No tube drainage was necessary and the air collections resolved spontaneously within days. 

Four cases have been reported of persistent subcutaneous nodules at sites of hepatitis B vaccination due to aluminium sensitization (58). Symptoms included pruritic, sore, erythematous, and in two cases hyperpigmen-ted, subcutaneous nodules, persisting for 8 months to 2 years. All the patients were positive for aluminium salts in patch tests, while immunization against hepatitis B was successful. 

Subcutaneous injection is commonly followed by local soreness and induration. Children sometimes develop... 

In contrast to the experimental techniques, computer models of the residual limb and prosthetic socket have the potential to estimate interface pressures for the entire residuum and inde are not limited to the interface but can also provide information regarding the subcutaneous tissue stresses. Nola and Vistnes and Daniel et al. have found that initial pathological changes in pressure sore formation occur in the muscle directly overlying the bone and then spread outward toward the skin. Therefore, the subcutaneous stresses may be important when evaluating long-term prosthetic success. These subcutaneous stresses are particularly difficult to measure in vivo. 

In another case, a 22-year-old man developed a headache, shortness of breath, and a sore throat 1.5 hours after aspirating an unknown amount of the undiluted juice of Ecballium elaterium intranasally [47 ]. He responded to oxygen, methylprednisolone 1 g intravenously, and adrenaline 2 mg subcutaneously. 

Effects of Vitamin C Deficiency.—(i.) Infantile Scurvy.—This condition is found in children fed exclusively on sterilised or artificial dietaries, or by mothers whose milk is deficient in ascorbic acid. After a period of anaemia and irregular growth, the characteristic syndrome appears sore gums, periosteal haemorrhages at the joints, subcutaneous haemorrhages and haematuria. 

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