Sodium lauryl sulfate, in water

Aquacoat ECD (ethylcellulose polymer, acetyl alcohol, and sodium lauryl sulfate in water) Coating for tablets and capsules Repeat-dose toxicity with routine end points (90 days—oral rat) and reproduction toxicity (embryo-fetal study in rat) No adverse findings for general toxicity or reprotoxicity 29, 30... 

The independent measurements of surface tension were obtained by the tedious Wilhelmy plate method. Figure 3 illustrates such a calibration curve for one set of orifices and for five types of test fluids (methanol-water, ethanol-water, acetone-water, sodium lauryl sulfate in water saturated with methyl methacrylate, and polymethylmethacrylate latices). This is a "universal" calibration curve independent of the fluid being monitored. For the 63 data points shown in Figure 3, the least squares regression line is given by... 

Figure 5.9 The fraction of dose dissolved as a function of time for the danazol data [126], Symbols represent experimental points and the lines represent the fittings of (5.21) to data. Key (% sodium lauryl sulfate in water as dissolution medium) 1.0 0.75 0.50 T 0.25 0.10.

Table 5.1 Estimates for k and 6 obtained from the fitting of (5.24) to dana-zol data, Figure 5.10. (a) Percentage of sodium lauryl sulfate in water, (b) Determination coefficient.

Figure 3.3.7. (a) Surface tension vs. concentration of a surfactant, sodium lauryl sulfate, in water, (b) Surface adsorption isotherm in a gas-liquid system. 

Chem. Anaiysis 28% Sodium lauryl sulfate in water CAS 151-21-3 EINECS/ELINCS 205-788-1... 

Chem. Descrip. Sodium lauryl sulfate in water (70%)... 

Besides the test substance, a positive control substance (a known skin irritant, 1% sodium lauryl sulfate in distilled water) and a negative control (untreated patch) are applied to the skin. When a vehicle is used for diluting, suspending, or moistening the test substance, a vehicle control patch is required, especially if the vehicle is known to cause any toxic dermal reactions or if there is insufficient information about the dermal effects of the vehicle. 

Figure 1 shows the results obtained by Francois and Skoulios (27) on the conductivity of various liquid crystalline phases in the binary systems water-sodium lauryl sulfate and water-potassium laurate at 50 °C. As might be expected, the water-continuous normal hexagonal phase has the highest conductivity among the liquid crystals while the lamellar phase with its bimolecular leaflets of surfactant has the lowest conductivity. Francois (28) has presented data on the conductivity of the hexagonal phases of other soaps. She has also discussed the mechanism of ion transport in the hexagonal phase and its similarity to ion transport in aqueous solutions of rodlike polyelectrolytes. 

Detergent Fractionation—a wetting agent, usually sodium lauryl sulfate, in combination with an electrolyte, usually magnesium sulfate, is added to the crystallizing oil or fat to allow the crystals to be suspended easily in the aqueous phase. The water phase with the crystals is separated from the liquid phase by means of... 

Sodium dodecyl sulfate (SDS, also known as sodium lauryl sulfate) in distilled water (w/v) (Caution This is an irritant. Wear gloves and face mask when weighing out the powder). 

FIGURE 8.5 Light scattering from a dilute solution of sodium lauryl sulfate in a water and salt solution. Data have been plotted using Equation 8.26. Reprinted from Phillips and Mysels (1955). Copyright 1955 American Chemical Society. 

A dry elixir is a novel dosage form developed by spray-drying actives and excipients dissolved or suspended in ethanol/water mixtures. One example is a dry elixir in which the feed solution contained actives, dextrin, and sodium lauryl sulfate in a mixture of ethanol/water (48). The spray-dried product was spherical in shape with a smooth surface and a mean diameter of 13 pm. A comparison with the active in powder form revealed a major decrease in dissolution time from >60 to 2 min. 

In an autoclave are placed 140 gm of a 25% aqueous solution of sodium lauryl sulfate, 4200 ml of distilled water, and a solution of 46.5 gm of ammonium persulfate in 500 ml of water. The mixture is warmed to 80°C while, over a period of 1 hr, a monomer emulsion obtained by dispersing 3500 gm of 2-ethylhexyl acrylate and 70 gm of a 25% aqueous solution of sodium lauryl sulfate in 1-liter of distilled water is added. By the end of the addition period, the polymerization is substantially complete. The latex has a solid content of 37%, a surface tension of 56 dynes/cm, a pH of 2.0, and an average particle size between 0.03 and 0,06 jum. 

Detergents are designed to be effective in hard water meaning water containing calcium salts that form insoluble calcium carboxylates with soaps These precipitates rob the soap of Its cleansing power and form an unpleasant scum The calcium salts of synthetic deter gents such as sodium lauryl sulfate however are soluble and retain their micelle forming ability even m hard water... 

The kinetics of vinyl acetate emulsion polymeriza tion in the presence of alkyl phenyl ethoxylate surfactants of various chain lengths indicate that part of the emulsion polymerization occurs in the aqueous phase and part in the particles (115). A study of the emulsion polymerization of vinyl acetate in the presence of sodium lauryl sulfate reveals that a water-soluble poly(vinyl acetate)—sodium dodecyl sulfate polyelectrolyte complex forms, and that latex stabihty, polymer hydrolysis, and molecular weight are controlled by this phenomenon (116). 

Detergents are substances, including soaps, that cleanse by micellar- action. A large number of synthetic detergents are known. One exanple is sodium lauryl sulfate. Sodium lauryl sulfate has a long hydrocarbon chain terminating in a polar- sulfate ion and forms soap-like micelles in water. 

Water serves as a base value in this test and sodium lauryl sulfate as a well-known irritating surfactant. Lauryl ether sulfate served as a substance with high sales volume and good skin tolerance. As was to be expected, lauryl ether sulfate scored only slightly better than lauryl sulfate. Sulfosuccinate values obtained were classified under little skin roughening effect. ... 

The active ingredients in a shampoo play three fundamental roles. Some allow water to wash away the substances that make hair dirty. Others adhere to hair to impart a desirable feel and texture. The rest are emulsifiers that keep the mixture from separating into its components. To accomplish these effects, ingredients combine two types of interactions a strong attraction to water (hydrophilic) and an aversion to water (hydrophobic). It may seem that these properties are incompatible, but shampoos contain molecules that are designed to be simultaneously hydrophilic and hydrophobic. One example is sodium lauryl sulfate, our inset molecule. The ionic head of the molecule is hydrophilic, so it interacts attractively with water. The hydrocarbon tail is hydrophobic, so it interacts attractively with grease and dirt. Molecules of the shampoo associate with hydrophobic dirt particles to form hydrophilic clumps that dissolve in water and wash away. 

Composition of Emulsion, The prototype oil/water emulsion described in Table I contained ingredients typical of a large number of cosmetic products, although simplified somewhat to avoid analytical problems. The aqueous phase contained sodium lauryl sulfate (SLS) as emulsifier, 0,2% (19 n ) DEA as precursor to NDEIA and 0,1% benzoic acid as preservative. 

JR Crison, ND Weiner, GL Amidon. Dissolution media for in vitro testing of water-insoluble drugs Effect of surfactant purity on in vitro dissolution of carbama-zepine in aqueous solutions of sodium lauryl sulfate. J Pharm Sci 86 384-388, 1997. 

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