Dissolution, in vitro

Stomach Promote rapid Control intrinsic dissolution In vitro/in vivo correlation... 

Esbelin B, Beyssac E, Aiache JM, Shiu GK, Skelly JP. A new method of dissolution in vitro, the Bio-Dis apparatus comparison with the rotating bottle method and in vitro in vivo correlations. J Pharm Sci 1991 80(10) 991. 

Siewert M, Dressman JB, Cynthia KB, Shah VP. FIP/AAPS guidelines for dissolution/in vitro release testing of novel/spe-cial dosage forms. Pharm Ind 2003 65(2) 129-134. 

DISSOLUTION/IN VITRO RELEASE OF SPECIAL DOSAGE FORMS... 

El-Zein H, Riad L, Elbary AA. Evaluation of carbamazepine dissolution—in vitro and in vivo evaluation. Int J Pharm 1998 168 169-174. 

Fleisch, H., Russell, R. G. G., Francis, M. D. Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 165, 1262 (1969)... 

Golomb G, Schlossman A, Saadeh H, Levi M, Van Gelder JM, Breuer E. Bisacylphosphonates inhibit hydroxyapatite formation and dissolution in vitro and dystrophic calcification in vivo. Pharm. Res., 1992, 9, 143-148. 

Siewert, M., Dressman, J., Brown, C. K., and Shah, V. P. (2003), FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms, AAPS PharmSciTech, 4, E7. 

A special case was concerned with measurement of uranium aerosols generated when DU munitions penetrate armored vehicles (Parkhurst 2003). In this study, DU penetrators were fired at a tank and another armored vehicle and the aerosols were collected by different means (filter cassettes, cascade impactors, five-stage cyclone, and a moving filter). Wipe samples were also collected from surfaces and deposition trays. Analysis included particle size distribution, morphology, uranium oxide phases, and dissolution in vitro. The uranium mass was determined by different methods radioanalytical beta spectrometry for some filters and ICPMS, ICP-AES, and KPA for other samples. 

Dressman JB, Vertzoni M, Goumas K, Reppas C (2007) Estimating drug solubility in the gastrointestinal tract. Adv Drug DeUv Rev 59 591-602 El-Zein H, Riad L, El-Bary AA (1998) Enhancement of carbamazepine dissolution in vitro and in vivo evaluation. Int J Pharm 168 209-220... 

Table 4.1 Chapter 5). Wool fibres have been optimized to allow maximum recovery when unpacked and set. Also, their dissolution in vitro has been of utmost importance since the problems generated by asbestos (see water diffusion and hydrolysis of siloxane bonds Chapters 5 and 7). Biodegradable glass fibres have been developed accordingly (Chattier, 1997). 

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