Sodium disulfide

Butyrolactone with sodium sulfide or hydrosulftde forms 4,4 -thiodibutyric acid (168) with sodium disulfide, the product is 4,4 -dithiodibutyric acid... 

Further work elucidated the stmcture of the dyes in this group by synthesizing trichioroarylthiazinones (18) from an o-aminoaryl mercaptan (19) and chloranil (20) treatment with sodium disulfide replaced the halogens by mercapto groups. 

Many other routes to produce thioglycohc acid have been iavestigated (9). To try to minimise by-products, nucleophilic agents other than alkah sulfhydrates have been claimed, eg, thiosulfates, sodium disulfides, thiourea, xanthogenic acid derivatives, and sodium trithiocarbonates (10). These alternative methods, which require reduction of the disulfides or hydrolysis of carboxymethylthio derivatives, seem less competitive than those usiag alkah sulfhydrates. 

When treated with sodium disulfide in ethanol, deca-2,4,6,8-tetrayne (53) gives dithiafulvene 54 rather than 1,2-dithiins 55 (67CB107). 

In case a small amount of sodium disulfide separates in a layer at the bottom, it should be taken up with a little more alcohol and added to the chloronitrobenzene solution. 

Sodium disulfide for the in situ preparation of organic disulfanes R2S2 may also be prepared from the elements in 1,2-dimethoxyethane at 70 °C in the presence of catalytic amounts of an aromatic hydrocarbon or ketone [22]. 

Sodium hydrogen sulfide, or Sodium disulfide, or Sodium polysulfide... 

This is prepared from 2-nitrochlorobenzene and sodium disulfide in ethanol, and the reaction residue after recovery of the ethanol by steam distillation is known to be of limited thermal stability. On one occasion, a container (atypically with closed vents) of bulked residues totalling over 2 t exploded violently while awaiting collection for disposal. It seems remotely possible that an aci-nitro thioquinonimine species derived from 2-nitrobenzenethiol may have been involved. 

There is a long history of the preparation of explosive solids or oils from interaction of diazonium salts with solutions of various sulfides and related derivatives. Such products have arisen from benzene- and toluene-diazonium salts with hydrogen, ammonium, or sodium sulfides [1,5] 2- or 3-chlorobenzene-, 4-chloro-2-methylbenzene-, 2- or 4-nitrobenzene- or 1- or 2-naphthalene-diazonium solutions with hydrogen sulfide, sodium hydrogen sulfide or sodium mono-, di- or poly-sulfides [l]-[4,7], 4-Bromobenzenediazonium solutions gave with hydrogen sulfide at -5°C a product which exploded under water at 0°C [2], and every addition of a drop of 3-chlorobenzenediazonium solution to sodium disulfide solution... 

Germanium(II) sulfide, 4419 Gold(III) sulfide, 0116 Iron disulfide, 4401 Iron(II) sulfide, 4400 Iron(III) sulfide, 4404 Manganese(II) sulfide, 4706 Manganese(IV) sulfide, 4707 Mercuiy(II) sulfide, 4607 Molybdemun(IV) sulfide, 4719 Potassium sulfide, 4670 Rhenium(VII) sulfide, 4891 Ruthenium(IV) sulfide, 4895 Samarium sulfide, 4899 Silver sulfide, 0026 Sodium disulfide, 4812 Sodium polysulfide, 4813 Sodium sulfide, 4811 Strontium sulfide, 4901 Tantalum(TV) sulfide, 4903... 

Dinitrochlorobenzene (95) reacts with pyridine to form 2,4-dinitrophenylpyridinium chloride (103), a reactive intermediate which readily reacts with a variety of nucleophiles. The reaction of (103) with hydrogen sulfide yields 2,2, 4,4 -tetranitrodiphenylsulfide (104), which on nitration-oxidation with fuming nitric acid, yields 2,2, 4,4, 6,6 -hexanitrodiphenylsulfoxide (105). The sulfide (104) is also formed from the reaction of two equivalents of 2,4-dinitrochlorobenzene (95) with sodium thiosulfate or sodium disulfide in aqueous ethanol. ... 

Tetrathionaphthalenes and their corresponding selenium analogues are synthesized by reaction of tetrachloro-naphthalenes 197 with / -generated sodium disulfide or with sodium diselenide (Equation 132). The yields of the sulfur analogues were found to be dependent on the method of disulfide generation (Table 14) <2001HAC287>. 

Thiopyran derivatives may be formed when a sulfide participates in an aldol transformation. An excellent example is the formation of 2H-thiopyran-5-carbaldehyde (19a) from benzaldehyde and acetaldehyde in the presence of sodium disulfide (Scheme 11 A).196... 

Of the several methods described for the production of thiosalicylic acid, only the following are of preparative interest heating of o-halogenated benzoic acids with an alkaline hydrosulfide at i50-200° in the presence of copper or copper salts,1 5 or by substitution of sodium sulfide at 200° 2 by reduction of dithiosalicylic add with glucose,3 or metals 4,5 in alkaline solution. The dithiosalicylic add is prepared by treating diazo-tized anthranilic acid with sodium disulfide in alkaline solution.4... 

TICIj thallium trichloride10 4. NajS2 sodium disulfide... 

Another point worth mentioning is the reduction of substituted nitro-benzenes by sodium disulfide in aqueous methanolic solution. This reaction was shown to be largely influenced by the presence of electron- donating or electron-withdrawing substituents (ref.8). The effect of substituents fits the Hammett equation well, the slope p-value being + 3.55, thus leading the authors to propose the disulfide anion as the reductive species. 2- and... 

These directions have been used equally successfully with twice, one-third, and one-fifth the amounts specified. The reaction of chloro- or bromoacetal with sodium disulfide results in the formation of a considerable quantity of the corresponding monosulfide which is not subsequently reduced to mercaptan. Polysulfides are, however, easily reduced to mercaptans. 1,1,11 -Tetramethoxyethyl poly sulfide has been prepared from commercially available dimethyl chloroacetal in a similar fashion. A 10-hour heating period and the addition of 5 g. of potassium iodide per 100 g. of acetal are recommended in the latter preparation. 

Heating 1,8-dichloroanthraquinone with sodium disulfide or diselenide in dimethylformamide (DMF) leads to pentacyclic systems 217 [78IJC(B)673]. The formation of heterocyclic systems of type 217 and... 

Sodium hydrogen sulfide, or Sodium disulfide, or Sodium polysulfide See entry DIAZONIUM SULFIDES AND DERIVATIVES (references 1—4) See other DIAZONIUM SALTS... 

Iron disulfide, 4395 Iron(II) sulfide, 4394 Iron(III) sulfide, 4398 Manganese(II) sulfide, 4701 Manganese(IV) sulfide, 4702 Mercury(II) sulfide, 4602 Molybdenum(IV) sulfide, 4714 Potassium sulfide, 4665 Rhenium(VII) sulfide, 4885 Ruthenium(IV) sulfide, 4889 Samarium sulfide, 4893 Silver sulfide, 0035 Sodium disulfide, 4806 Sodium polysulfide, 4807 Sodium sulfide, 4805 Strontium sulfide, 4895... 

Berzas Nevado et al. [138] developed a new capillary zone electrophoresis method for the separation of omeprazole enantiomers. Methyl-/ -cyclodextrin was chosen as the chiral selector, and several parameters, such as cyclodextrin structure and concentration, buffer concentration, pH, and capillary temperature were investigated to optimize separation and run times. Analysis time, shorter than 8 min was found using a background electrolyte solution consisting of 40 mM phosphate buffer adjusted to pH 2.2, 30 mM /1-cyclodextrin and 5 mM sodium disulfide, hydrodynamic injection, and 15 kV separation voltage. Detection limits were evaluated on the basis of baseline noise and were established 0.31 mg/1 for the omeprazole enantiomers. The method was applied to pharmaceutical preparations with recoveries between 84% and 104% of the labeled contents. 

Very good yields (ca. 90%) are obtained by reacting sodium disulfide in methanol, at pH 9, with a,y-diacetylenic carbonyl compounds (Eq. 6).22... 

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