Sodium acetate benzoate

Yadav, G. D., and M. M. Sharma, Kinetics of Reaction of Benzyl Chloride with Sodium Acetate/Benzoate Phase Transfer Catalysis in Solid-Liquid System, /iW[Pg.35]

Sodium acetate CH3COONa Sodium succinate (CHaCOONa), Sodium benzoate CeHjCOONa Sodium formate HCOONa i Sodium oxalate fCOONa) J Sodium salicylate HOCeH COONa... 

Sodium acetate reacts with /p-nitrophenyl benzoates to give mixed anhydrides if the reaction is conducted in a polar aprotic solvent in the presence of a crown ether. The reaction is strongly accelerated by quartemary nitrogen groups substituted at the orthc position. Explain the basis for the enhanced reactivity of these compounds. 

Systematic investigations were carried out for the preparation of cellulose acetate of D.S. 2,65 and other mixed esters which included cellulose acetate-propionate, cellulose acetate-butyrate, cellulose acetate-benzoate and cellulose acetate-methacrylate. The experimental conditions were optimised for maximum yield of the ester. Flat osmotic membranes were developed from these esters and characterised for their osmotic and transport properties. The nmmbra-nes were evaluated in a reverse osmosis laboratory test-cell using 5OOO ppm sodium chloride solution at 40 bars pressure. Table 1 presents the typical performance data of these membranes. 

Reacting this with sodium methoxide leads to the formation of an epoxide— 9-(2, 3 -anhydro- 8-luxofuranosyl)adenine (36.1.9). Finally, heating this epoxide with sodium acetate or benzoate opens the epoxide ring in the dimethylformamide-water system to make the corresponding dihydroxy derivative, vidarabine [12,13]. 

The effect of structural variation and the use of different caboxylate salts as cocatalysts was investigated by Pietikainen . The epoxidation reactions were performed with the chiral Mn(III)-salen complexes 173 depicted in Scheme 93 using H2O2 or urea hydrogen peroxide as oxidants and unfunctionalized alkenes as substrates. With several soluble carboxylate salts as additives, like ammonium acetate, ammonium formate, sodium acetate and sodium benzoate, good yields (62-73%) and moderate enantioselectivities (ee 61-69%) were obtained in the asymmetric epoxidation of 1,2-dihydronaphthalene. The results were better than with Ai-heterocycles like Ai-methylimidazole, ferf-butylpyridine. 

While high polymers of /3-lactones can also be formed by cationic polymerization, most of the commercial production seems to be by the anionic route. Carboxylate salts such as sodium acetate or benzoate are commonly the initiators, but other nucleophiles, such as triethylamine, betaine, potassium f-butoxide, aluminum and zinc alkoxides, various metal oxides and tris(dimethylamino)benzylphosphonium chloride (the anion of which is the initiator), are of value. Addition of crown ethers to complex the counter cation increases the rate of reaction. When the reaction is carried out in inert but somewhat polar organic solvents, such as THF or ethyk acetate, or without solvent, chain propagation is very fast and proceeds without transfer reactions. 

Reverse-phase chromatography has been used extensively for the determination of saccharin. Smyly et al. (30) and Eng et al. (39) used /rBondapak Cl 8 and 5% acetic acid for the determination of saccharin. Based on this work, an Association of Official Analytical Chemists (AOAC) collaborative study was conducted, and the method using a mobile phase buffered to pH 3 with sodium acetate and modified with 3% isopropanol was adopted. Webb and Beckman (61) used this method successfully for the separation of saccharin from aspartame, caffeine, sodium benzoate, and artificial colors and flavors. Veerabhadrarao et al. (27) added methanol to the mobile phase (methanol acetic acid water, 4 1 1, v/v) for improved separation of saccharin from caffeine, benzoic and p-hydroxybenzoic acids, vanillin, aspartame, acesulfame-K, and dulcin. Saccharin was also determined using LiChrosorb Cl8 and 4 6 v/v methanol phosphate buffer,... 

Acetyl )thiooxindole may be prepared by fusing together thio-oxindole and A,A -diphenylacetamidine to give the anil (217), which affords the acetyl compound on alkaline hydrolysis.573 Acetylation and benzoylation of thiooxindole are possible by using mixtures of acetic anhydride and sodium acetate or benzoic anhydride and sodium benzoate, respectively.575... 

Sodium acetate, 3-normal III, VII Sodium bromide> 0.5-normal IV Sodium benzoate, III Sodium carbonate, 3-normal III, VI, IX, XI... 

A reversed-phase HPLC post-column ion-pair extraction system was developed by Kim and Stewart [71, 72] for the analysis of carboxylic acid drugs and their salts (sodium formate, sodium acetate, 3-bromopropionic acid, 6-aminocaproic acid, 11-bromoundecanoic acid, 1-heptanesulfonic acid, / -n i t rophcny 1 acetic acid, sodium benzoate, sodium salicylate, valproic acid, probenecid, naproxen, ketoprofen, ibuprofen, mefenamic acid, flufenamic acid, and cefuroxime sodium) using a-(3,4-dimethoxy-phenyl)-4,-trimethylammoniummethylcinnamonitrile methosulfate... 

Lubricants To reduce the friction between the granules and the die wall during compression and ejection of the tableting process Water-insoluble metal stearates, stearic acid, talc Water-soluble boric acid, sodium chloride, benzoate and acetate, sodium or magnesium lauryl sulfate Carbowax 4000 or 6000... 

Lubricants PEG 6000 is most frequently used, alone or with sodium stearyl fumarate, sodium benzoate, sodium chloride, sodium acetate, or D,L-leucine. 

Finally, an aspartic acid residue is necessary for full catalysis and this residue is thought to use its CO2 group as a general base. A chemical model shows that the hydrolysis of f> nitrophenyl acetate in aqueous acetonitrile containing sodium benzoate and imidazole follows the rate law rate — <[p-nitrophenyl acetate] [benzoate] [imidazole]. Suggest a mechanism for the chemical reaction. 

Alkyl phenyl sulfones (piCj,27) are nearly as acidic as esters hence they are readily deprotonated by n-BuLi, LDA in THF, or EtMgBr in THF to give a-metalated sulfones. Their reaction with aldehydes gives a mixture of diastereomeric P-phenylsul-fone alkoxide adducts. Reductive elimination of the benzenesulfinate moiety from the adduct to produce the alkene is usually slow. To minimize side reactions, the hydroxyl group is first converted to an acetate, benzoate, mesylate, or /7-toluenesul-fonate and then treated with an excess of sodium amalgam [Na(Hg), prepared by adding small pieces of sodium to mercury] in methanol to furnish the trans-dlk n P... 

What is the pH of a 0.10 M solution of sodium benzoate / = 6.3 X 10 for benzoic acid, CgHyCOOH. Would this solution be more or less acidic than a 0.10 M solution of sodium acetate K = 1.8 X 10 for acetic acid, CH3COOH. 

Acetic, citric, lactic, and tartaric acids and their salts (potassium sorbate, potassium or sodium benzoate, sodium propionate, sodium acetate or diacetate, and sodium lactate) have been tested and approved as dipping or spraying treatments (Geomaras et al., 2005). 

Acyloxonium ions (Section 7.3) are stabilized by heavy anions. The formation of acyloxonium ions is also assumed, this time as non-isolated intermediates, in the solvolysis of some tosylates. In reaction (7,12) with sodium acetate, the introduction of an acetyl group at position 6 and migration of benzoate to position 5 testify to the presence of a benzoxonium intermediate. Likewise, solvolysis of sulfonates presenting a frani -vicinal acetamido group involves an oxazolinium cation 7.28, the analogue of an acyloxonium. 

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