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Cefuroxime sodium

An additional example of lactone hydrolysis includes the API lovastatin (9). In addition to lactone cleavage reactions, lactone formation can also occur as in the case of the API cephalosporin cefuroxime sodium (Fig. 4) (10). [Pg.54]

A reversed-phase HPLC post-column ion-pair extraction system was developed by Kim and Stewart [71, 72] for the analysis of carboxylic acid drugs and their salts (sodium formate, sodium acetate, 3-bromopropionic acid, 6-aminocaproic acid, 11-bromoundecanoic acid, 1-heptanesulfonic acid, / -n i t rophcny 1 acetic acid, sodium benzoate, sodium salicylate, valproic acid, probenecid, naproxen, ketoprofen, ibuprofen, mefenamic acid, flufenamic acid, and cefuroxime sodium) using a-(3,4-dimethoxy-phenyl)-4,-trimethylammoniummethylcinnamonitrile methosulfate... [Pg.312]

Figure A15-1. Lactone formation for cefuroxime sodium or cephalothin [2]. Figure A15-1. Lactone formation for cefuroxime sodium or cephalothin [2].
Cefuroxime sodium 0.75-1.5 g iVq. Shr 90% q.Shr q.S-12hr q.12-24 hr Absorbed weii when giyen intraperito-neaiiy may cause rare aiiergic interstitial nephritis may cause bleeding from impaired prothrombin biosynthesis Dose after dialysis Dose for GFR <10 1.0 g q. 12 hr... [Pg.921]

Wozniak TJ, Hicks JR. Cefuroxime Sodium. In Rorey K, ed. Analytical Profiles of Drug Substances, Vol. 20. San Diego Academic Press, 1991 209-36. [Pg.458]

Stiles, M.L. Allen, L.V., Jr. Fox, J.L. Stability of ceftazidime (with arginine) and of cefuroxime sodium in infusion-pump reservoirs. Am.J.Hosp.Pharm., 1992, 49, 2761-2764... [Pg.301]

Marble, D.A. Bosso, J.A. Townsend, R.J. Compatibility of clindamycin phosphate with aztreonam in polypropylene syringes and with cefoperazone sodium, cefonicid sodium, and cefuroxime sodium in partial-fill glass bottles. Drug Intell.Clin.Pharm., 1988, 22, 54-57... [Pg.316]

Das Gupta, V. Stewart, K.R. Stability of cefuroxime sodium in some aqueous buffered solutions and intravenous admixtures. J.Clin.Hosp.Pharm., 1986, 11, 47-54 [5% dextrose saline stability-indicating simultaneous degradation products cefazolin (IS)]... [Pg.316]

Some cephem analogs (cephaprin sodium, cefuroxime sodium, cefotaxime sodium, cefoperazone sodium, cefadroxil, ceftazidime, cefazolin sodium and cefaclor) can be determined spectrophotometrically based on formation of ion-pair complex with ammonium reinecekate. In acidic medium at 25 + 2°C, as the reaction products, the complex, absorbing at 525 nm, was formed according to the scheme [49] ... [Pg.122]

See other pages where Cefuroxime sodium is mentioned: [Pg.12]    [Pg.230]    [Pg.614]    [Pg.54]    [Pg.3959]    [Pg.991]    [Pg.465]    [Pg.1749]    [Pg.70]    [Pg.70]    [Pg.247]    [Pg.314]    [Pg.1600]    [Pg.4]    [Pg.121]    [Pg.121]    [Pg.314]    [Pg.1359]    [Pg.1600]    [Pg.171]    [Pg.375]   
See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]

See also in sourсe #XX -- [ Pg.140 ]

See also in sourсe #XX -- [ Pg.20 , Pg.209 ]



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