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Single chain Fv protein

To compensate for that weak interaction, researchers have directly linked Vh and Vi by adding peptide sequences that covalently hold them together. The product is caUed a single-chain Fv protein or sFv... [Pg.280]

Eirek S, Draper J, Owen MRL, Gandecha A, Cockburn B, Whitelam GC (1993) Secretion of a functional single-chain Fv protein in transgenic tobacco plants and cell suspension cultures. Plant Mol Biol 23 861-870. [Pg.962]

Flink MA, Griep RA, Borst JW, van Hoek A, Eppink MHM, Schots A, Visser AJWG (2000) Structural dynamics of green fluorescent protein alone and fused with a single chain Fv protein. J Biol Chem 275(23) 17556-17560... [Pg.296]

As discussed above, wheat has been used only rarely for molecular farming. Thus far, the only example of a pharmaceutical protein produced in wheat is a single chain Fv antibody, which was expressed using the Ubil promoter and achieved a maximum expression level of 1.5 pg g 1 dry weight [77]. Transgenic wheat producing Aspergillus phytase has also been reported [78]. [Pg.65]

CP coat protein CtxB cholera toxin B subunit scFv single chain Fv antibody fragment TMOF trypsin modulating oostatic factor MAB monoclonal antibody GFP green fluorescent protein CPV Canine parvovirus BHV Bovine herpes virus FMDV Foot and mouth disease virus HCV Hepatitis C virus HRV Human rhino Virus MEV Mink enteritis virus MHV Murine hepatitis virus MV Measles virus RSV Respiratory syncytial virus... [Pg.79]

Cooke, S.P, R.B. Pedley, R. Boden, R.H. Begent, and K.A. Chester, In vivo tumor delivery of a recombinant single chain Fv tumor necrosis factor-alpha fusion protein. Bioconjug Chem, 2002.13(2) 385. [Pg.380]

Kipryanov, S. M, Little, M, Kropshofer, H., Breitling, F., Gotter, S., and Diibel, S. (1996) Affinity enhancement of a recombinant antibody, formation of complexes with multiple valency by a single-chain Fv fragment-core Streptavidin fusion. Protein Eng 9,203—211... [Pg.499]

Single-chain Fv (a phyto chrome) 5 pg g 1 soluble protein Antigen binding Homogeneous [14]... [Pg.133]

Leclerc E, Liemann S, Wildegger G, Vetter SW, Nilsson F (2000) Selection and characterization of single chain Fv fragments against murine recombinant prion protein from a synthetic human antibody phage display library. Hum Antibodies 9 207-214. [Pg.722]

Berdichevsky, Y. Lamed, R. Frenkel, D. Gophna, U. Bayer, E. A. Yaron, S. Shoham, Y. Benhar, I., Matrix-assisted refolding of single-chain fv- cellulose binding domain fusion proteins, Protein Expr. Purif. 1999, 17, 249-259... [Pg.246]

Gilbert, I. Schiffmann, S. Rubenwolf, S. Jensen, K. Mai, T. Albrecht, C. Lankenau, A. Beste, G. Blank, K. Gaub, H. E. Clausen-Schaumann, H., Double chip protein arrays using recombinant single-chain fv antibody fragments, Proteomics 2004, 4, 1417-1420... [Pg.248]

IgG-single chain Fv fusion proteins Imatinib methanesulfonate Immtmoglobulin... [Pg.381]

Boado RJ, Lu JZ, Hui EK, Pardridge WM (2010) IgG-single chain Fv fusion protein therapeutic for Alzheimer s disease Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey. Biotechnol Bioeng 105 627-635... [Pg.526]

See other pages where Single chain Fv protein is mentioned: [Pg.721]    [Pg.826]    [Pg.516]    [Pg.1179]    [Pg.496]    [Pg.721]    [Pg.826]    [Pg.516]    [Pg.1179]    [Pg.496]    [Pg.18]    [Pg.85]    [Pg.80]    [Pg.188]    [Pg.212]    [Pg.206]    [Pg.286]    [Pg.420]    [Pg.475]    [Pg.496]    [Pg.51]    [Pg.213]    [Pg.74]    [Pg.373]    [Pg.374]    [Pg.397]    [Pg.394]    [Pg.481]    [Pg.46]    [Pg.210]    [Pg.211]    [Pg.237]    [Pg.1575]    [Pg.225]    [Pg.241]    [Pg.245]    [Pg.394]    [Pg.427]    [Pg.549]    [Pg.90]   
See also in sourсe #XX -- [ Pg.826 ]



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Protein chain

Single chain

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