Hormones, sexual

The vascular wall is a target for sexual hormones. In the particular case of estrogens, specific receptors have been found in both endothelium and vascular smooth muscle cells (VSMC) (Venkov et al. 1996 Karas et al. 1994). The trophic effects of estrogens on the endothelium have been advocated as crucial against initiation and promotion of atherosclerosis. Thus, cellular and animal models,... 

The analysis of steroid sexual hormones and related synthetic compounds in WW, soil, sludge, and sediment samples is a challenging task. This is due to both the complex environmental matrices and the requirement of low detection limits. Therefore, the use of complicated, time- and labor-consuming analytical procedures is necessary. 

Rats are sensitive to sexual hormones, unsuitable for the testing of dopamine agonists due to dependence on prolactin for establishment and maintenance of early pregnancy (1). 

Estradiol is one of the main female sexual hormones it is also the structural backbone for the engineering of some synthetic estrogens, such as ethynyl estradiol or mestranol, used in human hormone treatments. Both natural and synthetic estrogens are classified as endocrine disrupting chemicals (EDCs).6,362 Many of these substances and their metabolites end up in the environment where... 

The main objective of our study wasto recover tocopherols, but it is also possible to recover phytosterols, which are products with high added value, since they are used for the formulation of margarine and the syntheses of sexual hormones. 

Disturbance of reproduction. Quite a number of allelochemicals are known to influence the reproductive system of animals, which ultimately reduces their fitness and numbers. Antihormonal effects could be achieved by mimicking the structure of sexual hormones. These effects are not known for alkaloids yet, but have been confirmed for other natural products. Estrogenic properties have been reported for coumarins, which di-... 

Saturation of the enzyme ADH is already achieved at a blood alcohol concentration of 0.5%o with full enzyme activity occurring at 0.2-0.5%o. Thus a maximum rate of alcohol degradation is reached at these relatively low concentrations. There is no induction of the enzyme ADH following chronic alcohol consumption. Higher alcohol concentrations as well as protein deficiency, sexual hormones, thyroidal hormones, etc. may even cause a decrease in ADH activity. 

Clinically important, potentially hazardous interactions with antidiabetics, sexual hormones... 

Sexual hormones seem to be responsible for the transition from the developmental, uphill phase of life into the postdevelopmental, downhill period, characterized by the slow age-related decay of brain performance terminated by natural death (Fig. 6 in Knoll 2001). Weighty arguments speak in favor of the assumption that the slow, continuous age-related decline of enhancer regulation in the mesencephalic neurons plays a key role in the progressive decay of behavioral performances with the passing of time (see Sect. 3.5.1.1 for details). 

Examples of these characteristic changes are shown in Figs. 3.16 and 3.17. Sexual hormonal regulation starts working in the rat with full capacity only... 

Ruzicka L, Hofmann K. Sexual hormone XXIV. Uber die Aniagerung von Acetylen an die 17-standige Ketogruppe bei trans-Androsteron und A -trans-Dehydro-androsteron. Helv Chim Acta 1937 20 1280-1282. 

Butenandt A, The female sexual hormone. XI. Constitution of the follicular hormone. 2. The degree of saturation and Bie aromatic character of the follicular hormone, Z. Physiol. Chem., 223,147-168 (1934). NB Historical value only. Gave K = 0.44 x 10 , i.e.,... 

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