Sennae

Parts Tinnevelly Senna fruit 15 Parts Aniseed (crushed)... 

Parts Senna leaves 20 Parts Elder flowers... 

That the degree of comminution on its own is not the only factor involved in the kinetics-of the release of the active principles, but that evidently the nature and amount of the accompanying substances also play an essential part, has been demonstrated in the case of the sennosides in aqueous preparations (hot extractions and cold macerates) from senna fruits and senna leaves [3],... 

The result of taking into account the three factors mentioned - dose - degree of comminution - method of extraction - should be a tea that has an optimal amount of active constituents. But, at present ihere are very few studies which answer the often posed question What proportion of the active principles in the drug pass over into the tea With a hot-watcr infusion of chopped senna... 

Irritant or stimulant laxatives increase peristalsis by direct action on the intestine. An example of an irritant laxative is cascara sagrada and senna (Senokot). 

Cascara sagrada or senna—Pink-red, red-violet, red-brown, yellow-brown, or black discoloration of urine may occur. 

DDS 100 Plus Capsules—docusate, casanthranol Doxidan Capsules—docusate, casanthranol, sorbitol Nature s Remedy—cascara sagrada, aloe, lactose Peri-Colace—docusate, casanthranol, sorbitol, parabens Senokot-S tablets—docusate, senna concentrate, lactose... 

Albumin, aminophylline, aspirin, heparin, insulin, metoclopramide, NSAIDs, muromonab-CD3 (OKT3), opiates, penicillins, propafenone, quinidine, senna, sulfonamide antimicrobials, and vancomycin... 

Diphenylmethane derivatives (e.g., bisacodyl) and anth-raquinones (e.g., senna) have a selective action on the nerve plexus of intestinal smooth muscle leading to enhanced motility. The onset of effect is rapid but the effects can be harsh (cramping), depending on the dose taken. Castor oil is another member of this class that is used less frequently. 

Slow-transit constipation can be treated with chronic administration of osmotic laxatives. Tegaserod maleate 6 mg orally twice daily is an acceptable treatment. Senna, bisacodyl, and other stimulants should be used only when the others fail to deliver the desired effect. 

Senna (ExLax, Senokot) 1 7.2 mg orally as needed Second-line agent after bulk laxatives... 

For most nonhospitalized persons with acute constipation, the infrequent use (less than every few weeks) of most laxative products is acceptable however, before more potent laxative or cathartics are used, relatively simple measures may be tried. For example, acute constipation may be relieved by the use of a tap-water enema or a glycerin suppository if neither is effective, the use of oral sorbitol, low doses of bisacodyl or senna, or saline laxatives (e.g., milk of magnesia) may provide relief. 

If additional therapy is warranted, the use of supplemental fiber with or without a stool softener is appropriate. Lactulose, sorbitol, bisacodyl, or senna can be used occasionally. 

Medium-grain fatty rice bran was the best material for reducing weed emergence (Palmer amaranth Amaranthuspalmeri S. Wats, and ivyleaf momingglory Ipomoea hederacea Jacq. followed by sicklepod Senna obtusifolia (L.) H. S. Irvin Bameby, hemp sesbania Sesbania exaltata (Raf.) Cory and prickly sida Sida... 

Salvito DT, Senna RJ, Federle TW (2002) Environ Toxicol Chem 21 1301... 

SGOT Senna glutamic oxalacetic acid transaminase... 

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