Cassia senna

The most important anthraquinone glycosides are sennosides, found in the senna leaves and fruits (Cassia senna or Cassia angustifolia). These are, in fact, dimeric anthraquinone glycosides. However, monomeric anthraquinone glycosides are also present in this plant. 

N.A. Cassia senna L. Anthraquinone, beta-sitosterol, rhein, dianthrone glucosides, sennosides A, sennosides B, naphthalene glycosides, aloe-emodine, mucilage.99 100 Laxative, stimulant, cathartic, anticancer, cathartic. 

Furthermore, plants containing anthranoids, including senna (Cassia senna) and cascara (.Rhamnus purshiana), and soluble fibers, including guar gum and psyllium, can decrease the absorption of drugs (Fugh-Berman, 2000 Table 4.1). 

Oroxylum indicum (Bignoniaceae), PS — eEF-2 (DNA, TOPII) Cassia senna (Fabaceae), Aloe vera,... 

Oroxylum indicum [leaf] (Bignoniaceae), Cassia senna (Fabaceae), Aloe vera, A. spp., Asphodelus microcarpus [tuber], Xanthorrhea australis [flower] (Liliaceae), Rheum spp. (Polygonaceae), Tectona grandis [teak wood] (Verbenaceae) Angelica archangelica [root],... 

Coumarins and furanocoumarins, which serve as potent defence compounds in the Apiaceae and Rutaceae, occur in a few, mostly unrelated, species. Only in the genus Psoralea do they have a wide distribution. An-thraquinones, which are potent Na+, K+-ATPase inhibitors and strong purgatives, occur widely in the genus Cassia (Senna), but otherwise only occasionally in Andira and Abrus. 

Senna concentrate Laxative Cassia senna Senna... 

The leaves and fruits of Cassia angustifolia and Cassia senna (senna) contain laxative anthranoid derivatives. Mutagenicity testing of sennosides has produced negative results in several bacterial and mammalian systems, except for a weak effect in Salmonella typhimurium strain TA102 (1,2). No evidence of reproductive toxicity of sennosides has been found in rats and rabbits (3). 

Senna. Senna. Cassia senna. W. II. 520. Folia. The leaves. 

Cassia senna (L.) (C. acutifolia), known as Alexandrian senna, Aden senna, or Nubian senna C. angustifolia Vahl, known as Indian senna, Tinnevelly senna, and Meca senna (Franz, 1993)... 

Fig. 7,8 Sennae fructus Senna pods Cassia senna L, (Alexandrian senna) Cassia angustifoiia VAHL (Tinevelly senna) Caesalpiniaceae DAB 10, PhEur I, OAB, Helv Vll, MD. LISP XXII...

Senna. Dried leaflets of Cassia senna L. (C. acuti-... 

Syn Cassia acutifolia Delile Cassia angustifolia Vahl Cassia lanceolata Forssk. Cassia senna L. Senna acutifolia (Delile)... 

C16H12O5, Mr 284.27, orange needles, mp. 209-210 °C, uv ,a, 431 nm (C2H5OH). An octaketide that occurs in senna leaves (Cassia senna, Fabaceae), rhubarb roots, in chrysarobinum (see chrysarobin), lichens (Parmelia species), and fungi (Aspergillus and Penicillium species), as well as in glycosidically bound form in Cassia species. It has a weak spasmolytic activity. 

Caryophyllaceae, Chenopodiaceae, Clusiaceae, Combreta-ceae, Ericaceae, Euphorbiaceae, Fabaceae, Lythraceae, Po-lygonaceae, Rhamnaceae, Rhizophoraceae, Saxifragaceae, Scrophulariaceae ( ), Simaroubaceae, Sonneratiaceae, Sola-naceae, Urticaceae, and Xanthorrheaceae. In the Fabaceae, anthraquinones are almost exclusively found in the genus Cassia Senna) (Dahlgren et al., 1981 Zenk and Leistner, 1968). 

Figure 21 Structure of bianthrones from Cassia senna. Sennoside A R = R = COOH (-t-j-fomi. Sennoside B R = R s COOH, meso form. Sennoside C R = COOJt and R = CH2OH (+)-fonn. Sennoside D R = COOH and Ri = CH2OH, meso form. Glu = glucose.

Sennoside A Dianthrone 0-glycoside Cassia senna, C. angustifolia)... 

Source Cassia senna L. (syn. C. acutifoli Del. Senna alexandrina Mill.) and C. an-gustifolia Vahl (syn. Senna alexandrina Mill.) (Family Leguminosae or Fabaceae). 

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