Sennae folium

Cape Aloe jB = Cortex Frangulae (7 = Cortex Rhamni Purshianae D = Rhizoma Rhei E = Folia Sennae. The spot colours quoted were obtained with the untreated chromatogram by inspection in UV light... 

For severe vacuity weakness, subtract Rhubarb and add a small amount of Folium Sennae Fan Xie Ye). 

Formulas that promote bowel movement containing harsh herbs such as Da Huang (Rhei rhizoma), Fan Xie Ye [Sennae folium) and Mang Xiao (Natrii sulfas) move downward, and should be used with caution. 

Alexandrian Senna Pods Aniseed Arnica Flower Bearberry Leaf Cape Aloes Can/i fructus Centaurii herba Crataegi folium cum flore Dandelion Root Echinaceae pallidae radix Eucalypti aetheroieum Fennel... 

Tinnevelly Senna Pods Urticae folium/herba... 

Examples of how the composition is listed include Sennae folium, 415-500 mg, corresponding to 12.5 mg of hydroxyanthracene glycosides, calculated as Sennoside B or Valerianae radix 900 mg. 

SENNA LEAF, Sennae folium The dried leaflets of both of the Senna species are also used medicinally. The leaves of both contain the same amount (not less than 2.5%) of anthracenes and for this reason Pharmacopoeias permit the use of either species or of a mixture of the leaves of both the Alexandrian and Tinnevelly types. 

This method is generally useful for the separation of drug extracts containing a high proportion of ballast substances, e.g. mucilages from Sennae folium. 

In Sennae folium extract (2) a R, value depression of sennoside A and specifically of sennoside B occur, caused by the mucilages also extracted from the plant material with. 50% methanol. To avoid this effect the circular TLC method can be used (see Fig. 9). Senno,side D (R, — 0,5,5) is more highly concentrated in. Sennae folium extracts (2) tlian in Sennae fructus extracts (1). Senno,side C can be localized at R, — 0.7. Rhein is detectable as a yellow zone at R, 0.8 and its 8-0-glucoside is found between scnno.side D and C. 

Sennae folium (upper Segment) A sennoside A 0 sennoside D... 

The CTLC of Sennae folium und Sennae fructus shows as two prominent circle, sennoside A and B (—> test A/B) in the inner parts of both segments. The bands of sennoside D (—>D) and C are found slightly below the aloin test (—> test Al). Rhein (tc.st Rh) is clearly. seen in Sennae fructus extracts. The influence of mucilagines on the R, value of. sennoside B results in a dwelling circle (CTLC) and causes an R, value depression in the picture of the ascending TLC (compare with Pig.s. 7,8). 

For analysis of sennoside,s in. Sennae folium or fructus, the. solvent. system and detection method descriped in Fig, 7, 8, chap, 2) should be used. 

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