Sennae fructus

Fig. 7,8 Sennae fructus Senna pods Cassia senna L, (Alexandrian senna) Cassia angustifoiia VAHL (Tinevelly senna) Caesalpiniaceae DAB 10, PhEur I, OAB, Helv Vll, MD. LISP XXII...

Pudelko-Koerner, C. (1998) Quantitative near-infrared reflectance spectroscopy of sennosides from Sennae fructus angustifoliae in in-process and quality control including method validation Pharmazeutische Industrie 60, 1007-1012. 

C. Pudelko-Korner, Quantitative Near-Infrared-Reflection-Spectroscopy of Sennosides in Sennae fructus angustifoliae in Processing and Quality Control as well as Validation of these Methods, Pharma Technol. J., 19(1), 57-67 (1998). 

Alexandrian Senna Pods Aniseed Arnica Flower Bearberry Leaf Cape Aloes Can/i fructus Centaurii herba Crataegi folium cum flore Dandelion Root Echinaceae pallidae radix Eucalypti aetheroieum Fennel... 

Sennae fructus angustifoiiae Solidaginis virgaureae herba... 

Setmae foliunt or fructus are extracted with 50% methanol 20pl is used for TIC. Senna... 

Drug sample I Sennae fructus (methanolic extract, 20 xl)... 

In Sennae folium extract (2) a R, value depression of sennoside A and specifically of sennoside B occur, caused by the mucilages also extracted from the plant material with. 50% methanol. To avoid this effect the circular TLC method can be used (see Fig. 9). Senno,side D (R, — 0,5,5) is more highly concentrated in. Sennae folium extracts (2) tlian in Sennae fructus extracts (1). Senno,side C can be localized at R, — 0.7. Rhein is detectable as a yellow zone at R, 0.8 and its 8-0-glucoside is found between scnno.side D and C. 

Sennae fructus (lower segment) B sennoside B Al aloin... 

The CTLC of Sennae folium und Sennae fructus shows as two prominent circle, sennoside A and B (—> test A/B) in the inner parts of both segments. The bands of sennoside D (—>D) and C are found slightly below the aloin test (—> test Al). Rhein (tc.st Rh) is clearly. seen in Sennae fructus extracts. The influence of mucilagines on the R, value of. sennoside B results in a dwelling circle (CTLC) and causes an R, value depression in the picture of the ascending TLC (compare with Pig.s. 7,8). 

For analysis of sennoside,s in. Sennae folium or fructus, the. solvent. system and detection method descriped in Fig, 7, 8, chap, 2) should be used. 

PudeUco-Koerner, C., Quantitative Near-Infrared Reflectance Spectroscopy of Sennosides from Sennae fructus angustifoliae in In-Process and Quality Control Including Method Validation, Pharmazeutische Industrie, 60, 1007-1012 (1998). 

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