Securinega

Securinine [3610-40-2] (137), C 2H 5N02, is the major alkaloid of Securinega surroticosa Rehd. and has been shown to arise from two amino acid fragments, lysiae (24) andtyrosiae (25). [Pg.557]

Senecio alkaloids, see Pyirolizidine alkaloids Secoisoquinoline alkaloids, 33, 231 (1988) Securinega alkaloids, 14, 425 (1973) Sinomenine, 2, 219 (1952)... [Pg.245]

East Africa. Dried leaves of Nicotiana tabacum and Securinega virosa are mixed in a paste and used externally to destroy worms... [Pg.272]

Haiti. Decoction of the dried leaf is taken orally for bronchitis and pneumonia . India. Juice of Securinega leucopyrus is mixed with the dried leaf and applied externally for parasites k Fresh leaf is mixed with corncob or Amorphophallus paeonifoUum to treat asthma ... [Pg.273]

Securinega suffruticosa (Pall.) Rehd. Yi Ye Chan (leaf, flower, twig) Securinine, allosecurinine, securinol, dihydrosecurinine, securitinine, phyllantidine.33 This herb may be toxic. Treat infantile paralysis, neurasthenia, neuroparalysis. [Pg.148]

Securinega virosa (Roxb.) Pax Hoffmann Bai Yin Shu (leaf, root) Virosine, norsecurinine, dihydrosecurinine, virosecurinin, viroallosecurinine, norsecurinine, fluggein.56 Leaves used as a maturative, a detergent, it has antibiotic activity. Root to treat teeth and gum disease. [Pg.148]

Dictamnus albus L. subsp. dasycarpus (Turcz.) Winter, Dictamnus dasycarpus, Fraxinella dictamnus Moench Securinega virosa (Roxb.) Pax Hoffmann Solanum lyratum Thunb., S. melongena L. [Pg.340]

Elaeagnus oldhumii Maixmowicz Securinega suffruticosa (PalJ.) Rehd. [Pg.373]

Ephedra distachya, E. equisetina, E. intermedia, E. monosperma, E. sinica Securinega viro Trachelospermum jasminoides... [Pg.460]

Phyllanthus urinaria, P. niruri, P. reticulatus, Securinega suffruticosa Phyllanthus urinaria, P. niruri, P. reticulatus... [Pg.467]

Senecio alkaloids, see Pyrrolizidine alkaloids Securinega alkaloids, 14, 425 (1973)... [Pg.381]

Carbon-13 n.m.r. assignments have been reported for a number of isomeric 3-butyl-5-methyloctahydroindolizines that were synthesized in studies of the trial pheromone of the Pharaoh ant, and for some closely related indolizidines. This work includes a detailed discussion of the preferred conformations of these compounds.15 Securinegine, a minor alkaloid from Securinega suffruticosa Rehd., is isomeric with securinine, and the structure (22) has been proposed.16... [Pg.62]

This alkaloid (C13H1503N mp 169-170° [a]D —450°) was first obtained from Phyllanthus discoides Muell. Arg. (134) and presently from Securinega suffruticosa Rehd. Its structure (146) was mooted on the basis of a spectral study and confirmed when it was obtained in excellent yield by the hydrogen peroxide oxidation of allosecurinine (147) (135). [Pg.293]

Phyllanthus discoides, Securinega siffraticosa (Euphorbiaceae), Securidaca longepedmculata (Fabaceae)... [Pg.105]

When B. officinalis was mistaken for a similar plant, Securinega suffruticosa, and was cooked in a soup used for muscle aches, lumbago, or as a tonic by 19 patients, 14 developed diarrhea, 10 had nausea and felt cold, nine had sensations of abdominal fullness, and seven vomited (3). Liver enzymes rose and the median times to median peak activities were 3 days for alanine transaminase, 2 days for aspartate transaminase, 5 days for alkaline phosphatase, and 12 days for gamma glutamyltranspeptidase. The liver damage was hepatocellular liver injury rather than cholestatic and marked jaundice did not develop. [Pg.1305]

DL-[2- C]Lysine [as (1)] and [2- C]-A -piperideine [as (2)] afforded securinine (3) in which the label was confined essentially to the asterisked carbon atom. Further, [i 5-6- H 6- C]-DL-lysine [as (1)] gave securinine without loss of tritium. Consequently C-6 of lysine does not undergo oxidation in the course of securinine biosynthesis and so the e-amino-group of (1) must be retained whilst the a-amino-group and carboxy-function are lost. The combined results are consistent with the hypothetical route to securinine shown in Scheme 1. This pathway will now gain more validity if alkaloids with structures similar to those of the proposed intermediates can be found in Securinega or related plants. [Pg.2]

Securinega suffructicosa Securinine Sesamum indicum Silybium marianum Silymarin Taxifolin Sophora flavescens Sphocar dipine Soybean isoflavones Daidzein Daidzin Genistein Genistin Glycitein Glyzitin... [Pg.389]

This relatively large and interesting group has not been reviewed. Fifty Securinega species have been screened for securinine (11) content. The optical... [Pg.457]

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