Salicylates Ascorbic acid

Bromophenol blue (3.0...4.6) aliphatic carboxylic acids [225 — 228] malonic and lactic acids [229] palmitic and lactic acids [230] malonic, glycolic, malic, citric, tartaric, ketoglutaric, galacturonic and oxalic acids [196] dicarboxylic acids, succinic acid [231] indoleacetic acid, trichloroacetic acid [232] palmitic acid, palmityl- and stearyllactic acid [223] benzoic, sorbic and salicylic acid [234] metabolites of ascorbic acid [235] chloropropionic acid [236] oligogalacturonic acids [237] amino acids, hydrocarbons, mono-, di- and triglycerides [238] xylobiose, xylose, glucose and derivatives [239] sugar alcohols [91] toxaphene [240]... 

Irreversible reaction of [18] iodine with acetylsalicylic acid, aethaverine, amidopyrine, ascorbic acid, benzo-caine, quinine, dihydrocodeine, fluorescein, glycine, hydrocortisone acetate, isoni-azid, metamizole, papaverine, paracetamol, phenacetin, phenol-phthalein, piperazine, resorcinol, salicylic acid, salicylamide, sulfaguanidine, thymol, triethanolamine, tris buffer detection by reaction chromatography... 

Alpha hydroxy acids (AHAs) are water-soluble substances and thereby penetrate the outermost epidermal skin layers. In contrast, beta hydroxy acids (BHAs) are lipid (fat) soluble and are capable of penetrating to the underlying layers of skin (the dermis) located 1-5 mm below the surface of the skinJ2 Most AHAs are derived from plant materials and marine sources. Commonly used AHAs include malic acid (found in apples), ascorbic acid (a common ingredient in numerous fruits), glycolic acid (a constituent of sugar cane), lactic acid (a component of milk), citric acid (naturally abundant in citrus fruits), and tartatic acid (found in red wine). A common BHA is salicylic acid (an ingredient in aspirin). 

N.A. Rubus chamaemorus L. Tocopherol, benzoic acid, salicylic acid, ascorbic acid, vitamin C.102-275 Laxative, tonic, treat cough and fever. 

The electrostatic effect of the poly(4-vinylpyridine)-Cu(II) catalyst was also reported by Dadze et al. 115). Oxidation of ascorbic acid, salicylic acid, and tri-t-butylphenol was accelerated and that of p-phenylenediamine retarded by the poly(4-vinylpyridine) ligand at lower pH. As described in Section IIIA, a polymer-metal complex behaves as a polycation in aqueous solution, and the reaction is sensitive to the charge of low-molecular-weight species. The electrostatic effect due to the polycationic domain of a polymermetal catalyst is also predominant in the oxidation of charged substrates. 

Oxidation by molecular O., Ascorbic acid, catechols, quinoline, salicylic I crill). Felllli FDTA. Cutlll,... 

Antagonists of vitamin K substances include dicoumarol, sulfonamides, antibiotics, a-tocopherol quinone, dihydroxysteanc acid glycide, salicylates, iodinin, warfarin. Synergists include ascorbic acid, somatotropinn (growth hormone), and vitamins A and E. 

The presence of other medicinals such as phenacetin, ascorbic acid, methapyreline hydrochloride among other analgesics does not affect the determinations of salicylamide, acetylsalicylic acid and salicylic acid. 

V. Kmetec, Simultonous determination of acetylsalicylic, salicylic ascorbic and dehydroascorbic acid by HPLC, J. Pharm. Biomed. Anal., 70 1073 (1992). 

Apelblat, A., Manzurola, E. (1989) Solubility of ascorbic acid, 2-furancarboxylic, glutaric, pimelic, salicylic, and o-phthalic acids in water from 279.15 to 342.15 K, and apparent molar volumes of ascorbic, glutaric, and pimelic acids in water at 298.15 K. J. Chem. Thermodyn. 21, 1005-1008. 

Meadowsweet was used widely as a headache remedy. It is considered that just walking through it clears the head. Analysis of the compounds in the plant shows that it contains flavonoids, salicylates, tannins, volatile oils and other compounds such as coumarin, mucilage and ascorbic acid. It is currently used as a food flavouring, in beverages. It is also reported to be used for dyspepsia, muscular pains and peptic ulcers. 

Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentrations. J Clin Pharmacol 1980 20 236-31. 

Incompatible with alkalis, heavy metal ions, especially copper and iron, oxidizing materials, methenamine, phenylephrine hydrochloride, pyrilamine maleate, salicylamide, sodium nitrite, sodium salicylate, theobromine salicylate, and picot-amide. Additionally, ascorbic acid has been found to interfere with certain colorimetric assays by reducing the intensity of the color produced. ... 

A significant increase in the measured COj concentration was observed after the addition of 10 mmol/1 of a-keto-isovaleric acid (148% increase from baseline), a-keto-isocaproic acid (120%), phenylacetic acid (100%), DL-a-keto-P-methyl-A-valeric acid (100%), homogentisinic acid (50%), P-phenylpyruvic acid (45%), hydroxyphenyl acetic acid (32%), propionic acid (25%), ace-toacetic acid (25%), hydroxyphenyl pyruvate acid (23%), and 20 mmol/1 of hydroxyphenyl lactid acid (65%) or salicylic acid (76%). A significant decrease was observed after the addition of 20 mmol/1 of ascorbic acid (33%), DL- -hydroxybutyric acid (25%) or imidazole lactic acid (25%). No effect after the addition of 10 mmol/1 of imidazole-4-acetic acid, methylmalonic acid, 5-hy-droxyindole acetic acid or 20 mmol/1 arginosuccinic acid, Z.-(+)-hydroxybu-tyric acid (E525). 

Animals may manifest toxicity to salicylates with signs and symptoms similar to those seen in humans. These may include fever, hyperpnea, seizures, respiratory alkalosis, metabolic acidosis, gastric hemorrhage, and kidney damage. Methemoglobinemia has also been seen in animals following salicylate toxicity. Activated charcoal has been used in animals. Methylene blue or ascorbic acid may be utilized for the treatment of methemoglobinemia. 

Drug-lab-food interactions Decreased ascorbic acid uptake when taken with salicylates may decrease effect of oral anticoagulants may decrease elimination of aspirins. 

Spectrophotometric determination of salicylic acid was done by Qu (29). 0.5 ml of sample solution containing up to 70 /jq of salicylic acid is mixed with NaCI (0.2 g) and 1 nM-pentachloronitrosyliridate (1 ml) and set aside in the dark for one hour. Then (0.2 ml) of 2% ascorbic acid solution is added, the mixture is diluted to 40 ml with 4M-HCI, and the absorbance is measured at 446 nm vs a reagent blank. Beer s law is obeyed from 0.5 to 13 /jq ml 1 of salicylic acid. No interference is caused by the presence of boric or benzoic acid. 

Other factors influence testing (e.g., fluid intake, urine concentration, ingestion of salicylates or ascorbic acid, and urinary tract infections). 

Scandium can also be separated from rare-earth and other metals by extraction as a complex of HTTA [8,9], or salicylate [10]. Xylene [8], CHCI3 [9], and mesityl oxide [10] have also been used for extraction of Sc. Scandium has been extracted from ascorbic acid medium with Aliquat 336S [11], or with acetylacetone in the presence of 3,5-dichlorophenol [12]. Macrocyclic ethers have also been used for extraction of Sc [13]. 

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