Safety factors conditions affecting

Personal factors, which affect health and safety, may be defined as any condition or characteristic of an individual which could cause or influence him to act in an unsafe manner. They may be physical, mental or psychological in nature. Personal factors, therefore, include issues such as attitude, motivation, training and human error and their interaction with the physical, mental and perceptual capability of the individual. 

Occupational health and safety - factors and conditions that can affect the well-being of persons within the workplace, i.e. employees, contractors, temporary workers and visitors. 

In harsh operational conditions environmental factors can affect the performance of DP which can lead to loss of the position control abiUty. For a Mobile Offshore Drilling Unit (MODU), loss of position without safe disconnection could result in critical damage not only to the well, but also to the subsea equipment. For an Offshore Support Vessel (OSV), loss of position could lead to colhsion with the nearby installation during operation or to damage to the subsea fadhties. In order to increase the safety and reliabiUty of a DP system, it is important to identify and quantify all influence factors and the way that they can affect the DP performance. For example bad weather condition is an effective factor on the position reference sensor or the local position reference system. Such operational conditions can vary from place to place and may have a dynamic nature in a specific location. Moreover, it is important to investigate safe recovery back to position, safe disconnection and reconnection when the loss of position is outside the safe operational range. 

Distribution mains shall be patrolled in areas where necessary to observe factors that may affect safe operation. The patrolling shall be considered in areas of construction activity, physical deterioration of exposed piping and supports, or any natural causes that could result in damage to the pipe. The frequency of the patrolling shall be determined by the severity of the conditions that could cause failure or leakage and the subsequent hazards to public safety. 

The major advantage of (fractional) oral clearance as a phenotypic trait is that its value is linearly related to the enzyme s catalytic activity, provided that first-order conditions are present. This requirement, along with any safety considerations, is the main reason the dose of an in vivo probe should be as low as possible, consistent with analytical considerations. Furthermore, it is possible to directly extrapolate this type of trait measure to the disposition of other drugs whose metabolism is mediated by the measured enzyme and also to place the trait value within a therapeutic context. On the other hand, estimation of oral clearance requires multiple blood and urine collections, often over many hours, that are an inconvenience for the study subject and require considerable amounts of analytical time and effort. Because of this, simpler and less time-consuming approaches have often been used. However, it is not always appreciated that such phenotyping tests provide only an indirect measure of metabolizing activity and may be affected by factors other than the enzyme s intrinsic clearance. In addition, it is difficult to relate an indirect trait measure to parameters that are of clinical importance, such as the drug s clearance. 

Whenever possible, the Army plans to dispose of nonstockpile chemical materiel on-site. However, there may be occasions when it is not feasible or practical for the Army to do so, and transportation to another disposal location may be required. Factors the Army intends to consider are population proximity and density, chemical weapon type, condition of the munitions, and public safety and environmental policy. In addition, the opinions and concerns of the affected states, local governments, and the public will affect the Army s decisions. For example, there is strong public opposition to incineration and transportation of chemical weapons across state boundaries. 

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