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Reverse multidrug resistance

Williams, A.B. and Jacobs, R.S. (1993) A marine natural product, patellamide D, reverses multidrug resistance in a human leukemic cell line. Cancer Letters, 71, 97. [Pg.260]

Wadleigh RW, Yu SJ (1988) Detoxification of iso thiocyanate allelochemicals by glutathione transferase in three lepidopterous species. J Chem Ecol 14 1279-1288 Werck-Reichhart D, Feyereisen R (2000) Cytochromes P450 a success story. Genome Biol 1 1-9 Williams AB, Jacobs RS (1993) A marine natural product, patellamide D, reverses multidrug resistance in a human leukemic cell line. Cancer Lett 71 97-102 Yazaki K (2006) ABC transporters involved in the transport of plant secondary metabolites. FEBS Lett 580 1183-1191... [Pg.228]

Lavie, Y., Cao, H-t., Volner, A., Lucci, A., Han, T. Y., Geffen, V., Giuhano, A. E., and Cabot, M. C., 1997, Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabohsm by inhibiting ceramide glycosylation in human cancer cells. J. Biol. Chem. 272 1682-1687. [Pg.281]

Merrit JE, Sullivan JA, Drew L, Khan A, Wilson K, Mulqueen M, Harris W, Bradshaw D, Hill CH, Rumsby M, Warr R (1999) The bisindolylmaleimide protein kinase C inhibitor, Ro 32-2241, reverses multidrug resistance in KB tumour cells. Cancer Chemother Pharmacol 43 371-378... [Pg.82]

Wakusawa S, Nakamura S, Tajima K, Miyamoto K, Hagiwara M, Hidaka H (1992) Overcoming of vinblastine resistance by isoquinolinesulfonamide compounds in adriamycin-resistant leukemia cells. Mol Pharmacol 41 1034-1038 Wakusawa S, Inoko K, Miyamoto K (1993) Staiuosporine derivatives reverse multidrug resistance without correlation with their protein kinase inhibitory activities. J Antibiotcs 46 335-337... [Pg.93]

Berberis fremontii, B beridaceae Ang. of N American folk medicine/it acts by reversing multidrug resistance, as a multidrug pump inhibitor of the human pathogen, Stc hylococcus aureus, thus acting synergistically with the plant antibiotics... [Pg.158]

Irciniasulfonic acid (629) was obtained from Ircinia sp. from Japanese waters. Spectroscopic and chemical analyses revealed it to consist of three different kinds of acids common fatty acids, a novel unsaturated branched CIO fatty acid and an isethionic acid. Irciniasulfonic acid (629) reverses multidrug resistance in human carcinoma cells caused by overexpression of membrane glycoprotein [498]. [Pg.714]

Table 1 The effects of carotenoids on reversing multidrug resistance (MDR) in human MDR1 gene-transfected mouse lymphoma cells... Table 1 The effects of carotenoids on reversing multidrug resistance (MDR) in human MDR1 gene-transfected mouse lymphoma cells...
Pommerenke EW.OsswaldH, Hahn EW, Volm M (1990) Activity of various amphiphilic agents in reversing multidrug resistance of L 1210 cells. Cancer Lett 55 17-23... [Pg.247]

Shudo N, Mizoguchi T, Kiyosue T, Arita M, Yoshimura A, Seto K, Sakoda R, Akiyama S (1990) Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel-blocking activity than their dihydropyridine counterparts. Cancer Res 50 3055-3061... [Pg.249]

Tolyporphyrin A from the microalga Tolypothrix nodosa reverses multidrug resistance in a Vinblastine-resistant population of human ovarian adenocarcinoma cells. In a synthesis of Tolyporphin A, four 0-benzyl groups were cleaved from the C-glycoside rings of 150.1 [Scheme 4.150] using zinc chloride and ethane-... [Pg.254]

Taxoids from Taxus cuspidata (the Japanese yew) inhibit P glycoprotein and are candidates for reversing multidrug resistance in cancer cells (5). [Pg.3304]

Toward the end of a phase I study of vinblastine plus oral ciclosporin to reverse multidrug resistance, three patients also received erythromycin to raise their ciclosporin concentrations all developed severe toxicity consistent with a much higher dose of vinblastine than was actually given (94). [Pg.3638]

Coon JS, Knudson W, Clodfelter K, et al. Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydroxystearic acid, reverses multidrug resistance. Cancer Res 1991 51(3) 897—902. [Pg.417]

Raederer, M. and Scheithauer, W. (1993) Clinical trials of agents that reverse multidrug resistance—a literature review. Cancer 72, 3553-3563. [Pg.14]

Thalicarpine (thaliblastine, TBL, NSC-68075) was found to reverse multidrug resistance in doxorubicin (ADR)-resistant murine leukemic P388/R-84 cells by direct interaction with P-glycoprotein, thereby increasing cellular ADR retention [323]. [Pg.168]

Zhou WJ et al (2012) Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein. Br J Pharmacol 166(5) 1669-1683... [Pg.119]

Bohnert, J.A. and Kern, WV. (2005) Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps. Antimicrobial Agents and Chemotherapy, 49 (2), 849-852. [Pg.155]

The bisindole alkaloids, conodiparines A-D (362-365) also showed appreciable activity in reversing multidrug resistance in vincristine-resistant KB cells (KB/VJ300, IC50 1-5 pg/ml) with the highest activity shown by conodiparine A (362) (ICjo 1.45 gg/ml) [237]. [Pg.426]

Sikic BI. Pharmacologic approaches to reversing multidrug resistance. Semin Hematol 1997 34 40-47. [Pg.777]

See other pages where Reverse multidrug resistance is mentioned: [Pg.254]    [Pg.379]    [Pg.43]    [Pg.46]    [Pg.49]    [Pg.71]    [Pg.92]    [Pg.169]    [Pg.369]    [Pg.379]    [Pg.70]    [Pg.107]    [Pg.1256]    [Pg.154]    [Pg.168]    [Pg.47]    [Pg.426]    [Pg.321]    [Pg.263]    [Pg.192]    [Pg.185]   
See also in sourсe #XX -- [ Pg.1256 ]



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