Taxus cuspidata

Taxus cuspidata rotating wall vessel laminar biomass and metabolite productivity growth [106]... [Pg.152]

Soule et al. [141] constructed a sparged, concentric cylinder bioreactor for the cultivation of suspensions of Pirus malus. Growth was reduced under all rotational conditions. Sun and Linden [106] employed a rotating wall vessel (Rotary Cell Culture System, Synthecon, Houston, TX, USA) to cultivate suspensions of Taxus cuspidata under laminar flow conditions. Shear rates were... [Pg.160]

Taxus cuspidata Taxus spp., Taxodium distichum, Torreya taxifolia, WoUemia nobilis... [Pg.520]

Taxus cuspidata Sieb. et Zucc. T. chinensis (Pily) Rehd. T. yunnanensis Cheng et L. K. Fu Zhu Shan, Huang Dao Shan (Yew tree) (bark, leaf) Taxol, baccatin, cephalomannine, 10-deacetylbaccatin, yunnanxana, abeotaxanes, taxinine E.33 Antineoplastic, anticancer, treat ovarian carcinoma. [Pg.161]

Taxus cuspidata, T. chinensis, T. yunnanensis Pileostegia viburnoides... [Pg.381]

Ailanthus altissima, Lycopodium clavatum, L. obscurum, L. selago, L. serratum Artemisia gmelini, Matricaria chamomilla, Melaleuca leucadendra, Piper cubeba Taxus cuspidata, T. chinensis, T. yunnanensis... [Pg.393]

Some plant glycosides and polysaccharides cross-react195,197 with reagents for blood-group antigens, and interesting cross-reactions were also shown by methylated-fucose haptens and L-fucose-specific lectins for example, it was found that 2-O-methyl-L-fucose was immunodominant in the Japanese yew (Taxus cuspidata), and that the 3-0-... [Pg.312]

Fett-Neto AG, DiCosmo F (1996) Production of paditaxel and related taxoids in cell cultures of Taxus cuspidata perspectives for industrial application. In DiCosmo F, Misawa M (eds), Plant cell culture secondary metabolism toward industrial application. CRC Press, Boca Raton, p 139... [Pg.100]

Taxuspine (taxoid) Taxus cuspidata (Japanese yew) (Taxaceae) [leaf]... [Pg.572]

This fairly straightforward concept of the stereochemical features defining the specificity of eel serum was, however, complicated by an unexpected finding extremely low concentrations (for example, 0.3 /Ag/ml) of an L-fucose-free polysaccharide from Taxus cuspidata com-... [Pg.277]

Kobayashi, J. Hosoyama, H. Wang, X.-X. Shigemori, H. Koiso, Y. IwasaM, S. Sasaki, T Naito, M. Tsumo, T. Effects of taxoids from Taxus cuspidata on microtubule depolymerization and vincristin accumulation in MDR cells. Bioorg. Med Chem. Lett., 1997, 7 393-398. [Pg.136]

Kosugi, K. Saki, J-L Zhang, S. Watanabe, Y Sasaki, H. Suzuki, T Hagiwara, H. Hirata, N. Hirose, K Ando, M. Tomida, A. Tsumo, T. Neutral taxoids from Taxus cuspidata as modulators of multidmg-resistant tumor cells. Phytochem., 2000, 54 839-845. [Pg.136]

Taxol is biosynthesized in 19 steps from GGPP that originates from precursors of the MEP pathway (Fig. 5). The biosynthesis of Taxol begins with the formation of the tricyclic diterpene skeleton of taxa-4(5),ll(12)-diene (17, 39). All genes for the enzymes in this early pathway have been identified in Taxus cuspidata and a taxa-4(5),ll(12)-diene synthase has been identified in several Taxus species. The mechanism of this di-TPS has been explored in detail (39). Taxa-4(5),ll(12)-diene is then hydroxylated by several cytochrome P450 taxoid oxygenases to yield a putative intermediate decorated with seven alcohol... [Pg.1838]

Taxoids from Taxus cuspidata (the Japanese yew) inhibit P glycoprotein and are candidates for reversing multidrug resistance in cancer cells (5). [Pg.3304]

Kobayashi J, Shigemori H, Hosoyama H, Chen Z, Akiyama S, Naito M, Tsuruo T. Multidrug resistance reversal activity of taxoids from Taxus cuspidata in KB-C2 and 2780AD cells. Jpn J Cancer Res 2000 91(6) ... [Pg.3304]

Fang, W. Wu, Y. Zhou, J. Chen, W. Fang, Q. Qualitative, and quantitative determination of taxol and related taxanes in Taxus cuspidata Sied et Zucc. Phytochem. Anal. 1993, 4, 115-119. [Pg.1578]

Synonyms Taxus baccata, Taxus cuspidata, Taxus brevifolia Taxus canadensis-, Taxus floridana American Yew Chinese yew English yew Japanese yew Ground hemlock Pacific yew Western yew... [Pg.2866]

Surprisingly, deer are able to eat the foliage of Taxus cuspidata and apparently suffer no harm. [Pg.2867]

Efforts to get access to improved manufacturing processes or improved application properties of paclitaxel resulted in two different pathways for the total synthesis of the natural product, as well as analogs. Furthermore, paclitaxel and/or precursors can be obtained under optimized conditions from cell cultures of Taxus media generated by hybridizing Taxus baccata and Taxus cuspidata in overall yields of about 130 mg 11 within two weeks [61]. Paclitaxel can also be obtained by the culture of appropriate microbial strains isolated from paclitaxel producing yew trees [62 - 64]. [Pg.114]

Taxol (Paclitaxel) production using free and immobilized cells of Taxus cuspidata. Biotechnol Bioeng 53 214-219. [Pg.962]

Mirjalili N, Linden JC (1996) Methyl jasmonate induced production of taxol in suspension cultures of Taxus cuspidata Ethylene interaction and induction models. Biotechnol Prog 12 110-118. [Pg.964]

TAP 29 484 TaqMan 84 TAR RNA decoys 231 Tarceva 143, 1122 Tasonermin 463, 479 Taste blindness 74 TATA box 764 Taurodeoxycholate 1376 Taxanes 140, 1252 Taxol 314, 835 Taxotere 101 Taxus cuspidata 950 TAXUS trial 315 Tazl 43... [Pg.1881]

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