Restlessness coffee

When use of the CNS stimulants causes insomnia, the nurse administers the drug early in the day (when possible) to diminish sleep disturbances. The patient is encouraged not to nap during the day. Other stimulants, such as coffee, tea, or cola drinks, are avoided. In some patients, nervousness, restlessness, and palpitations may occur. The vital signs are checked every 6 to 8 hours or more often if tachycardia, hypertension, or palpitations occur. Many times these adverse reactions will diminish with continued use as tolerance develops. If tolerance develops, the dosage is not increased. 

It has been estimated that beverage consumption may provide the following amounts of caffeine per cup or average measure coffee, 30-150 mg (average 60-80 mg) instant coffee, 20-100 mg (average 40-60 mg) decaffeinated coffee, 2-4 mg tea, 10-100 mg (average 40 mg) cocoa, 2-50 mg (average 5 mg) cola drink, 25-60 mg. The maximal daily intake should not exceed about 1 g to avoid unpleasant side effects, e.g. headaches, restlessness. An acute lethal dose is about 5-10 g. 

Caffeine is the most widely used of all the stimulants. Small doses of this chemical (50 to 200 mg) can increase alertness and reduce drowsiness and fatigue. The No-Doz tablet lists caffeine as the main ingredient. In addition, it affects blood circulation since the heart is stimulated and blood vessels are relaxed (vasodilation). It also acts as a diuretic. There are side effects. Large doses of over 200 mg can result in insomnia, restlessness, headaches, and muscle tremors ( coffee nerves ). Continued, heavy use may bring on physical dependence. (How many of you know somebody who cannot function in the morning until they have that first cup of coffee )... 

Chronic overdose. Excessive prolonged consumption of caffeine causes anxiety, restlessness, tremors, insomnia headache, cardiac extrasystoles and confusion diarrhoea may occur with coffee and constipation with tea. The cause can easily be overlooked if specific enquiry into habits is not made including children regarding cola drinks. Of coffee drinkers, up to 25% who complain of anxiety may benefit from reduction of caffeine intake. An adult heavy user may be defined as one who takes more than 300 mg caffeine/day, i.e. 4 cups of 150 ml of brewed coffee, each containing 80 20 mg caffeine per cup or 5 cups (60 20) of instant coffee. The equivalent for tea would be 10 cups at approximately 30 mg caffeine per cup and of cola drinks about 2.01. Plainly, caffeine drinks brewed to personal taste of consumer or vendor must have an extremely variable concentration according to source of coffee or tea, amormt used, method and duration of brewing. There is also great individual variation in the effect of coffee both between individuals and sometimes in the same individual at different times of life (see Sleep, above). 

Caffeine gives coffee its bitter taste and some people a feeling of restlessness. 

Caffeine Restlessness, agitation, insomnia, diueresis, GI disturbances, excitement Headache, fatigue, drowsiness, nausea or vomiting Antagonist of adenosine receptors, increase cAMP in neurons that have adenosine receptors Avoid caffeine, analgesics Average adult consumes about 200 mg per day. A cup of coffee contains 100-150 mg of caffeine, tea has 1/3 as much... 

There may be some adverse effects due to excessive caffeine intake, such as restlessness, headaches, heart palpitations, heartburn, and insomnia. Some individuals may have a toxic reaction to it. Ingestion by pregnant women and nursing mothers may have adverse effects on fetuses and babies caffeine crosses the placenta and gets into breast milk. Caffeine has a wide margin of safety. A lethal dose for most people would be the amount of caffeine found in about one hundred cups of coffee. 

Human Toxicity Acute poisoning Causes restlessness, anorexia, nausea, fever, vomiting, dehydration. Eventual bloody, syrupy or coffee-ground vomitus, tremors, delirium and coma can occur- May result in cardiovascular and respiratory collapse, shock, cyanosis and death, Clinical Toxicology of Commercial Products, R. E. Gosselin el of.. 

The increase in caffeine levels with concurrent use would seem to be established. There are no reports of caffeine toxicity arising from this interaction and one study found no increase in the pharmacodynamic or adverse effects of caffeine despite a large increase in the levels. However, an increase in the stimulant and adverse effects of caffeine (headache, jitteriness, restlessness, insomnia) may be possible in susceptible patients if they continue to consume large amounts of caffeine-containing food or drinks (tea, coffee, cola drinks, chocolate, etc.) or take caffeine-containing medications. They should be warned to reduce their caffeine intake if problems develop. It has been suggested that some of the adverse effeets of fluvoxamine (i.e. nervousness, restlessness and insomnia) could in fact be caused by caffeine toxicity. However, a preliminary study, as well as the study reported above, found that caffeine intake had a limited effect on the frequency of adverse effects of fluvoxamine. ... 

Established interactions. Based on the results of two studies, on a scale of 100 to 0, the relative potencies of these quinolones as inhibitors of caffeine elimination have been determined as follows enoxacin 100, pipemidic acid 29, ciprofloxacin 11, norfloxacin 9 and ofloxacin 0. From further studies, clinafloxacin appears to be similar to enoxacin (profound effect), pefloxacin to norfloxacin (to which it is metabolised modest effect), and fleroxacin, lomefloxacin, rufloxacin, and trovafloxacin appear to behave like ofloxacin (no effect). Patients taking enoxacin might be expected to experience an increase in the effects of caffeine (such as headache, jitteriness, restlessness, insomnia) if, for example, they continue to drink their usual amounts of caffeine-containing drinks (tea, coffee, cola drinks, etc.). They should be warned to cut out or reduce their intake of caffeine if this occurs. The authors of one report suggest that patients with hepatic disorders, cardiac arrhythmias or latent epilepsy should avoid caffeine if they take enoxacin for one week or more. The effects of pipemidic acid arc less, and those of ciprofloxacin, norfloxacin and pefloxacin arc probably of little or no clinical importance. Fleroxacin, lomefloxacin, ofloxacin, rufloxacin, and trovafloxacin do not interact. 

Overdose of coffee may result in restlessness, nervousness, excitement, insomnia, flushed face, frequent urination, stomach ache, nausea, tremors, talkativeness, periods of inexhaustibility, and irritability (Hughes et al. 1991). 

One can develop both a tolerance for the xanthines and a dependence on them, particularly caffeine. The dependence is real, and a heavy user (>5 cups of coffee per day) will experience lethargy, headache, and perhaps nausea after about 18 hours of abstinence. An excessive intake of caffeine may lead to restlessness, irritability, insomnia, and muscular tremor. Caffeine can be toxic, but to achieve a lethal dose of caffeine, one would have to drink about 100 cups of coffee over a relatively short period. 

While the effects of caffeine vary from person to person, a dose of 1,000 mg or more will generally produce adverse effects such as insomnia, restlessness, excitement, trembling, rapid heart beat with extra heart beats, increased breathing, desire to urinate, ringing in the ears, and heartburn. A fatal dose of caffeine appears to be more than 10 g or 170 mg/kg of body weight—about 80 to 100 cups of coffee in one sitting. 

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