Chemical recognition

S. M. Roberts, ed.. Molecular Recognition—Chemical and Biochemical Problems, The Royal Society of Chemistry, Cambridge, 1989. 

Keywords electronic nose principal component analysis pattern recognition chemical sensors sensor arrays olfaction system multivariate data analysis. 

Molecular Recognition Chemical and Biological Problems IT, Roberts, S. M., Ed. Royal Soc. Chem. Cambridge, 1992. 

Both the nonspecific and specific components of the immune system can be suppressed by chemicals, including drugs. It involves the suppression of maturation and development of immune cells. Both T and B cells develop in the bone marrow and thymus. This involves a complex series of changes in relation to antigen receptors and recognition. Chemicals can affect these processes, leading to a decrease in the number of mature T and B cells. This will result in inhibition of both the humoral and cellular responses. 

Roberts, S.M ed. Molecular Recognition-Chemical and Biochemical Problems. The... 

Combinatorial chemistry has matured from a field where efforts initially focused on peptide-based research to become an indispensable research tool for molecular recognition, chemical-property optimization, and drug discovery. Originally used as a method to primarily generate large numbers of molecules, combinatorial chemistry has been significantly influenced and integrated with other important fields such as medicinal chemistry, analytical chemistry, synthetic chemistry, robotics, and computational chemistry. 

Mathias JP, Stoddart JF (1989) Angew Chem Adv Mater 101 1129 e) Kohnke FH, Mathias JP, Stoddart JF (1989) In Roberts SM (ed) Molecular recognition Chemical and biochemical problems, The Royal Society of Chemistry, Cambridge, UK p 233... 

P. A. Bartlett, G. T. Shea, S. J. Telfer, and S. Waterman in S. M. Roberts, Ed., Molecular Recognition Chemical and Biological Prob-lems. Royal Society of Chemistry, London,... 

Appropriate substrate-catalyst matching can achieve interesting enantiomer recognition. Chemical kinetic resolution is observed during hydrogenation of 3-substituted itaconate esters with Rh-dipamp catalysts , and of various prochiral secondary alcohols with binap . 

As the reagent and the substrate approach each other, attractive and repulsive interactions occur. The discrimination between the various possible transition states depends upon the relative magnitudes of these interactions, which in turn depend upon the transition-state geometries. Unlike enzymatic reactions, which are usually controlled by attractive interactions due to site recognition, chemically induced discrimination is usually dependent upon differences in repulsive interactions. 

Barlett PA, Shea GT, Telfer SJ, Waterman S. Roberts SM, ed. Molecular Recognition Chemical and Biological Problem. London Royal Society of London, 1989 182-196. 

Over 200 compounds have been identified so far in the genus although approximately 120 of these are simple hydrocarbons and relatively ubiquitous in the plant kingdom. Nonetheless they may be important as possible recognition chemicals and mediators for oviposition by insect pests [14]. This chapter lists all the known compounds that have been isolated from the genus Cicer under 5 sections in the text. It also ascribes a biological activity to the compounds where applicable to the ecology of Cicer. Where possible, semi-systematic names have been... 

Bartlett PA etal. Molecular Recognition Chemical and Biological Prohlems Royal Society of Chemistry, London (UK), pp 182-186, 1989. 

Figure 2 Enantiomer separation of aliphatic oxiranes by com-plexation gas chromatography on nickel(ii) bis[3-(heptafluoro-butanoyl)-(1S)-19-ethylidene-camphorate] (0.125molkg in OV-101) between 70°C and 90°C. Column 25m x 0.25mm (i.d.) glass capillary. (From Schurig V and Betschinger F (1992) Metal-mediated enantioselective access to unfunctionalized aliphatic oxiranes prochiral and chiral recognition. Chemical Reviews 92 873-888.)...

Clay modified electrodes are used in fundamental studies of electron transfer, and in the construction of sensor devices. The ionic aqueous environment in the interlayer region is highly amenable to electrochemical processes. Furthermore, this enviromnent is controllable and fairly innocuous, allowing many different species to retain their activity. Molecular recognition, chemical catalysis, electrocatalysis, and preconcentration of analyte molecules are all applications of this class of modified electrodes. A condensed list of clay modified electrodes is given in Table 8.4. Reference (96), Table 6.1 on pages 280-281 contains a more comprehensive list. 

Bartlett, P.A., Shea, G.T., Teller, SJ. and Waterman, S. (1989) CAVEAT A Program to Facilitate the Structure-derived Design of Biologically Active Molecules, in S.M. Roberts (ed). Molecular Recognition Chemical and Biological Problems, Royal Society of Chemistry, pp. 182-196. 

Hunter, CA. (1994) Meldola lecture. The role of aromatic interactions in molecular recognition. Chemical Society Reviews,... 

Although chemical cues are obviously used in kin discrimination in larval amphibians, the nature of the kin recognition chemical signal(s) (pheromone)... 

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