Pseudomonas aeruginosa cepacia

Pseudomonas aeruginosa, Stenotropho-monas maltophilia and Burlcholderia cepacia, J. Antimicrob. Chemother. 2001, 48, 549-552. 

The stmcture of pyochelin (for a detailed bibliography, see (57)), a secondary siderophore of Pseudomonas aeruginosa and of Burkholderia cepacia was established (75) as 2-(2-o-hydroxyphenyl-2-thiazolin -yl)-3-methylthiazolidine-4-carboxylic acid. It consists of a mixture of two easily interconvertible stereoisomers (pyochelin I and II) differing in the configuration of C-2". They can be separated by chromatography, but in methanolic solution (not in DMSO) the equilibrium (ca. 3 1) is restored quickly. For a discussion of the mechanism of isomerization, see (57, 577). 

Zamri A, Abdallah MA (2000) An Improved Stereocontrolled Synthesis of Pyochelin, Siderophore of Pseudomonas aeruginosa and Burkholderia cepacia. Tetrahedron 56 249... 

Usually, total aerobic bacteria, molds, and yeasts are counted by using a standard plate count in order to test the microbial limits. The microbial limit test may be customized by performing a screening for the occurrence of Staphylococcus aureus, Pseudomonas aeruginosa, Pseudomonas cepacia, Escherichia coli, and Salmonella sp. [56],... 

Less is known about the pathways of PAH degradation by co-cultures than about the pathways of degradation by individual bacteria and fungi (Juhasz Naidu, 2000). Four bacteria Pseudomonas aeruginosa, Pseudomonas cepacia (=Burkholderia cepacia). Pseudomonas sp. and Ralstonia pickettii) and four fungi (Alternaria tenuis, Aspergillus terreus, Trichoderma... 

Riedel K, Hentzer M, Geisenberger O, Huber B, Steidle A, Wu H, Hoiby N, Givskov M, Molin S, Eberl L. N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms. Microbiology 2001 147 3249-3262. 

Two categories of microorganisms are cause for concern in preservation of topical semisolid products. They are those liable to cause pathogenic symptoms and include staphylococci and hemolytic streptococci. Pseudomonas aeruginosa and cepacia, and Escherichia coli, and microorganisms liable to cause spoilage, which include water and airborne molds and yeasts. The following section describes the properties of some commonly used preservatives. 

Achromobacter sp. Pseudomonas sp. Pseudomonas aeruginosa Pseudomonas putida By consortia of bacteria Psuedomonas cepacia AC1100... 

These findings prompted the development and evaluation of the currently available form of inhaled tobramycin, which is sterile and free of preservatives. The benefit of maintenance therapy with this inhaled tobramycin is supported by the results from two 24-week, multicenter, randomized, double blind, placebo-controlled clinical trials [6]. In these studies, patients with cystic fibrosis were at least six years of age, with an FEVj between 25% and 75% predicted. All subjects had evidence of colonization with Pseudomonas aeruginosa. Exclusion criteria included an elevated serum creatinine or colonization with Burkholderia cepacia, which is typically resistant to tobramycin. Subjects in the active treatment arm received inhaled tobramycin 300 mg twice daily through... 

Zhang, L Li, X.Z. and Poole, K. (2001) Fluoroquinolone susceptibilities of efflux-mediated multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Burkholderia cepacia. The Journal of Antimicrobial Chemotherapy, 48 (4), 549-552. 

Aronoff SC, Klinger JD. In vitro activities of aztreonam, piperacillin and ticarcillin combined with amikacin against amikacin-resistant Pseudomonas aeruginosa and P. cepacia isolates from children with cystic fibrosis. Antimicrob Agents Chemother 1984 25 279-280. 

Table 11.1-14. Lipase-catalyzed enantiomer-differentiating hydrolysis of esters of racemic primary alcohols in aqueous solution (PPL pig pancreas lipase, PCL Pseudomonas cepacia lipase, PCL-A Pseudomonas cepacia lipase, Sumitomo, PSL Pseudomonas sp. lipase, PAL Pseudomonas aeruginosa lipase, HLL Humicola lanuginosa lipase, CAL-B Candida antarctica B lipase, CRL Candida rugosa lipase).

Baeyer-Villiger oxidation has also been reported for aliphatic ketones. Several strains able to grow on various aliphatic or alicyclic substrates have been isolated, and it has been shown that their degradation often involves a Baeyer-Villiger oxidation. For example, it has beeen observed that Pseudomonas multivorans, Pseudomonas aeruginosa, Pseudomonas cepacia and Nocardia sp. are able to grow on tridecan-2-one l25-28l. 

Bacteria strains Burkholederia cepacia (1), Enterococcus durans (1), Enterococcus faecium (1), Enterococcus faecalis (2), Enterobacter aero genes (1) Enterobacter spp. (1), Escherichia coli (4), Klebsiella pneumoniae (4), Klebsiella oxitoca (1), Lactobacillus sp. (1), Proteus mirabilis (1), Pseudomonas aeruginosa (5), Staphylococcus aureus (6), Staphylococcus epidermidis (2), Staphylococcus spp. (2)... 

Pseudomonas aeruginosa S-7 Pseudomonas cepacia B-17 Pseudomonas fluorescens NS-7371 Flavobacterium sp. AB7 Acinetobacter calcoaceticus B28 Streptomyces sp. No. 2 Streptomyces sp. B6 Streptomyces flaveus Y 1 Without antagonist... 

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