Protein generation

Vale, R.D., Schnapp, B.J., Mitchison, T., Steuer, E., Reese, T.S., Sheetz, M.P. (1985b). Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell 43,623-fr32. 

Sakaida, S., Kyle, M. and Farber, J.L. (1990). Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress. Mol. Pharmacol. 37, 435-442. 

McQuibban GA, Gong JH, Wong JP, Wallace JL, Clark-Lewis I, Overall CM. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood 2002 100(4) 1160-1167. 

Our earlier research on the coupled binuclear copper proteins generated a series of protein derivatives in which the active site was systematically varied and subjected to a variety of spectroscopic probes. These studies developed a Spectroscopically Effective Model for the oxyhemocyanin active slte.(l) The coupled binuclear copper active site in tyrosinase was farther shown to be extremely similar to that of the hemocyanlns with differences in reactivity correlating to active site accessibility, and to the monophenol coordinating directly to the copper(II) of the oxytyroslnase site.(2) These studies have been presented in a number of reviews.(3) In the first part of this chapter, we summarize some of our more recent results related to the unique spectral features of oxyhemocyanin, and use... 

A modeT that accounts for the selective degradation of proteins based on the amino acid that is present on the amino- or N-end of nascent proteins. Intracellular processing of nascent, noncompartmentalized proteins generates the mature protein via the action of amino-terminal peptidases. In model studies using /3-galactosidase... 

Koga H, Shimada K, Hara Y, et al. (2004) A comprehensive approach for establishment of the platform to analyze functions of KIAA proteins generation and evaluation of anti-mKIAA antibodies Proteomics 4, 1412-1416. 

Several strategies have been developed to humanize the glycosylation patterns of proteins generated in transgenic plants. The first discussed here is the retention of glycoproteins within the ER. 

Oxidation of UQH2 by the iron-sulfur protein generates the semiquinone UQH , which then serves as the reductant for cytochrome bL. The reduced iron-sulfur protein transfers an electron to cytochrome cx and on to cytochrome c. Meanwhile, the reduced cytochrome bL passes an electron to cytochrome bu, which then contributes the electron for reduction of another molecule of UQ at a second site in the complex. 

Xue, Z. G., Cheraud, Y., Brocheriou, V., Izmiryan, A., Titeux, M., Paulin, D., and Li, Z. (2004). The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames. Exp. Cell Res. 298, 431-444. 

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