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Generation of Protein Diversity

Screening-based directed evolution requires the integration of techniques for the generation of protein diversity and high-through-put protein screening technology into a... [Pg.599]

The evolution of proteins in a modular fashion by fusion of segments of genes, each coding for a module of a compact structural unit of polypeptide, is thus a credible and attractive hypothesis for explaining the rapid generation of enzyme diversity. [Pg.354]

C. Touriol, S. Bomes, S. Bonnal, S. Audigier, H. Prats, A.C. Prats, and S. Vagner, Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons, Biol Cell 95, 169-178 (2003). [Pg.159]

See also Evolution of Myoglobin/Hemoglobin Proteins, Hemoglobin Variants, Thalassemias, Generation of Antibody Diversity... [Pg.1872]

Recount a hypothesis relating exons and functional domains to the generation and evolution of protein diversity. Differentiate between nucleotide sequence rearrangements by genetic recombination at the DNA level and by RNA splicing. [Pg.53]

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Generating Diversity

Protein diversity

Protein generation

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