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Variation, product control

The detection sensitivity of radiography is related among others to the properties and quality of industrial x-ray film systems. Changes of the products, variations due to different emulsions and combinations of products of different manufacturers can influence the decisive properties of film systems as classified in EN 584-1.To ensure the quality of industrial x-ray film systems a system for quality assurance open to all interested parties is proposed which is based on periodical round robin tests and quality controls of the manufacturer or an independent third party institution. [Pg.555]

The relation of rates of reduction with NaBH4 to variations in structure in a wide variety of monocyclic and bridged bicyclic compounds has also been discussed for example, a methyl a to a ketone slows the rate of reduction. Brown ° stated that reactions should not be discussed in terms of axial and equatorial attack, since the rates simply reflect differences in the energies of the possible transition states and not enough is known about the transition state to analyze it. He accepted th concepts of SAC and PDC, but preferred to call them steric strain contrpl and product stability control. ... [Pg.69]

In biochemical engineering processes, measurement of dissolved oxygen (DO) is essential. The production of SCP may reach a steady-state condition by keeping the DO level constant, while the viable protein is continuously harvested. The concentration of protein is proportional to oxygen uptake rate. Control of DO would lead us to achieve steady SCP production. Variation of DO may affect retention time and other process variables such as substrate and product concentrations, retention time, dilution rate and aeration rate. Microbial activities are monitored by the oxygen uptake rate from the supplied ah or oxygen. [Pg.14]

In a more perfect world, fuel properties would be the same from all producers everywhere. Unfortunately, this is not the case, and fuel properties vary according to production plant, feedstock variations and quality, production quality control, and the presence of contaminants picked up during storage and distribution. [Pg.43]

Conceptually the chemistries of all these polymerizations are similar because they are related to isobutene, which is by far the main component, and the compositions, structures, molar masses, and physical states of the corresponding products are controlled by a variation of solvent, tern-... [Pg.684]

Another fundamental state variable that can be regulated during the cycle is cavity pressure. Closed loop control of cavity pressure could automatically compensate for variations in melt viscosity and injection pressure to achieve a consistent process and consistency of molded products. Adaptive control methods have been developed to track the cavity pressure profile at one location in the mold. In these earlier works, cavity pressure control was handicapped by the absence of actuators for distributed pressure control, as conventional molding machines are equipped with only one actuator (the screw), which prevents the simultaneous cavity pressure control at multiple points in the mold. This problem has been solved with the development of dynamic melt flow regulators that allow control of the flow and pressure of the polymer melt at multiple points in the mold.[ °l... [Pg.1406]

Methods of transportation, including vehicles to be used, should be selected with care, and local conditions should be considered, including the climate and any seasonal variations experienced. Delivery of products requiring controlled temperatures should be in accordance with the applicable storage and transport conditions. [Pg.194]

Control charts are a plot of sample subgroup averages and subgroup variability (measured as the subgroup range or standard deviation) against the order of production. The control limits displayed on the charts are set at 3 standard deviations about the sample average and process variation see Eqs. (6) and (7), respectively,... [Pg.566]

An accurate statement of the weight or measure of each component, using the same weight system (metric, avoirdupois, or apothecary) for each component Reasonable variations may be permitted, however, in the amount of components necessary for the preparation in the dosage form, provided they are justified in the master production and control records ... [Pg.716]

In energy balance control schemes (e.g.. Fig. 16.7), energy balance variations control product composition, and the free variable is one of the product flows. [Pg.511]

Lipid extracted from human hair is similar in composition to scalp lipid [134]. Thus, the bulk of the extractable lipid in hair is free lipid however, cell membrane complex lipid is also partially removed by extraction of hair with lipid solvents or surfactants. In a sense, the scalp serves as a lipid supply system for the hair, with sebum being produced continuously by the sebaceous glands [135]. Sebum production is controlled hormonally by androgens that increase cell proliferation in the sebaceous glands, and this in turn increases sebum production [135,136], although seasonal and even daily variations in the rate of sebum production do occur [137]. [Pg.91]

Examples such as these provide motivation for professionals to consider the implications of product-to-product and service-to-service variation. Clearly, product variation is key to customer satisfaction and loyalty therefore, successful producers realize this and take appropriate actions to control the variation or quality of the products or services provided. [Pg.1856]

Well-known and documented techniques exist to monitor product variation while it is within the producer s environment. Most of the techniques require the observations or data to be statistically independent. That is, the data for a specific performance measurement are assumed to have no relationship to prior or successive observations. It is assumed that no correlation exists between data collected prior to or following a specific observation. The techniques used to monitor such data are collectively called statistical process control (SPC). These techniques are utilized in consumer-oriented industries. Some of the more prominent or useful techniques are presented in this chapter. Specifically, seven tools for SPC are reviewed, and their applicability is examined. Furthermore, common and improved approaches for process capability analysis are presented. [Pg.1857]

Figure 4.47 Corrosion controlled by mass transport of anodic reaction products variation of the dimensionless corrosion rate (Sherwood number) as a function of Reynolds number for corrosion of a steel pipe in 68% H2SO4 at 60 °C [20],... Figure 4.47 Corrosion controlled by mass transport of anodic reaction products variation of the dimensionless corrosion rate (Sherwood number) as a function of Reynolds number for corrosion of a steel pipe in 68% H2SO4 at 60 °C [20],...
GPC is used for polymer profiling, i.e., when MWD is not required - examples are production quality control, checking lot-to-lot variations, and analysis of competitors products. The technique has been applied to numerous polymers and resins, and to oligomers, e.g., tetrahydrofuran (THF) solutions of a mixture of PS oligomers, epoxy resins, or mixed dimethyl formamide tetrahydrofuran solutions of styrene butadiene latex. [Pg.272]

Variations in product composition are carefully monitored and controlled. To do this, a variety of modern control features are incorporated into the system, including temperature, pressure, level, and flow control loops. Product variation is the enemy of any chemical process. When product specifications are not met, customers will take their business elsewhere. [Pg.271]

This is because, as we shall see later on in this chapter, process variability can be shown to arise primarily from two sources both controlled and uncontrolled variation. Controlled variation does not have any known assignable cause arising from variation of the process or process material, whereas uncontrolled variation does. What must be ultimately discerned is which sources of variation can be shown to be the result of assignable causes that can lead to potential adulteration of the process and hence product. Keeping this in mind, we now can define what calibration and validation cGMPs are. [Pg.248]


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