Prioritization schemes

Fig. 13.4 A logistical nightmare. Processing orders from numerous vendors is very challenging. Shown here are 6111 compounds purchased from 30 different vendors. To alleviate this kind of ordering in the current process, only compounds from the preferred vendor list and a set of small vendors that have potential sources of novel compounds (compounds not found in the catalogs of larger vendors) were considered. A vendor prioritization scheme that assigns compounds to the top vendors (if compounds were available from multiple sources) was also put in place.

Compounds passing stringent criteria are assigned to vendors using vendor prioritization scheme... 

The goal of the prioritization scheme is to design the scores so that the overall worst looking compounds are de-emphasized and the best looking compounds are moved toward the top of the list. Thus, it is important to ensure that the best and the worst compounds are clearly separated and that the vast bulk of the population is in the middle. The normal distribution is ideally suited for this and thus it is advantageous to transform our component scores into a normal-like distribution. Enterprise Miner from SAS Institute was used to do this as it has a maximize normality transformation built into it. 

As risk assessment becomes more sophisticated and is extended to more chemicals, it will also be extended to smaller and smaller risks. Since it is not possible to regulate all risks, an important use of risk analysis must be to decide which chemicals should be regulated and to what degree. Under the Tbxic Substances Control Act (TOSCA), all new chemicals must be considered. The prioritization scheme for chemical testing is based upon a set of dichotomous criteria, toxicity, chemical reactivity, etc., which involve qualitative rather than quantitative risk analysis. As procedures for more quantitative analysis become available, the prioritization scheme will become more precise, (NAS/NRC, 1984). 

We ve all used to-do lists at one time or another, but the veteran time manager uses one with considerable zeal. Some time management books suggest elaborate prioritization schemes, multiple lists, fancy calendars, and so on. The tools of our trade will be much simpler a monthly calendar, an 8i X 11-inch lined pad of paper, and a diary or their electronic equivalents. The calendar is simply used to record aU events, appointments, and fixed-date deadlines. The pad of paper is used to track all activities, both to do and pending, as well as each day s activities. The diary is used to track who you talked to and what you did. Of course, in an age of ubiquitous personal computers and personal digital assistants, calendars, to-do lists, and diaries all have electronic counterparts. I... 

Another approach to prioritization is to employ the Pareto principle. Commonly known as the 80/20 rule, this principle was first discussed by Italian economist Vilfredo Pareto in the nineteenth century when studying the distribution of wealth in a number of countries. He observed that about 80 percent of the wealth in most countries was controlled by a consistent minority—about 20 percent of the people.2 This principle suggests that we should focus on those few tasks which produce the most significant results (Petersen and Halstead, 1983). When applied to the important and urgent prioritization scheme, the 20 percent of most the fruitful activities fall into quadrant II or priority 2, and it is on these activities that we should focus most of our effort (Douglass and Douglass, 1993, pp. 28-29). 

New information on substances with existing EQSs use of the EQS despite being outdated and therefore affecting policies inappropriately current environmental monitoring of die substance interim status of die current EQS availability of EQSs for die substance in other media substance identified by other prioritization schemes within Canada or... 

Oprea TI, Bologa CG, Edwards BS, Prossnitz ER, and Sklar LA. Post-High-Throughput Screening Analysis An Empirical Compound Prioritization Scheme./Biomo/Screen 2005 10 419-426. 

If loads within a utility system have different power requirements, it may be reasonable to protect critical loads by implementing a load prioritization scheme. 

This prioritization scheme (ARIO) will often be helpful, but strict adherence to it can sometimes produce the wrong prediction. In other words, there are many exceptions. As an example, compare the structures of acetylene and ammonia ... 

There are, of course, other exceptions to the ARIO prioritization scheme, but the exception shown above is the most common. In the vast majority of cases, it would be a safe bet to apply the four factors in the order ARIO to provide a qualitative assessment of acidity. However, to be certain, it is always best to look up values and verify your prediction. 

Prioritizing maintenance activities is central to a methodical, structured maintenance approach, in contrast to merely addressing maintenance issues in a reactive, short-term mode. From the preceding sections, it should be apparent that life-cycle asset management can be used to develop a prioritization scheme that may then be employed in a wider set of funding decisions, not only maintenance "go/no-go" decisions. This entails the methodical evaluation of each maintenance action against preestablished values and attributes such as the key performance indicators described in Chap. 12. 

It should be pointed out here that for any prioritization scheme, only a limited set of critical tests is performed to arrive at the EEC. Estimation of EEC is a difficult process, controlled by identifying correctly and accurately the source Inputs for the chemical. It may be accomplished in a localized aquatic situation but for most other systems, a bench-mark approach is used to predict the environmental distribution and persistence of the chemical. It... 

Grant DN, Bommer JJ, Pinho R, Calvi GM, Goretti A, Meroni F (2007) A prioritization scheme for seismic intervention in school buildings in Italy. Earthq Spectra 23(2) 291-314... 

Indication of which prioritization scheme is being used (Basic or Pairwise Comparison) and what weights have been entered for the three categories of evaluation criteria (financial considerations, implementation considerations, and potential impacts). 

Start with the BASIC prioritization scheme. Manually set values for the weights" for each criterion. Return to the LIST tab in EXPLORE and sort the strategies by score in descending order by clicking on the header for Total Score. ... 

To assign the configuration, we must first assign a prioritization scheme to the four atoms connected to the chirality center ... 

Among these groups, the double bond is assigned the third priority in our prioritization scheme, and we must continue to assign the first and second priorities. 

Our prioritization scheme indicates that the chirality center has the R configuration ... 

The chirality center has the S configuration, determined by the prioritization scheme shown here. 

This compound has two chirality centers, shown below. The following prioritization schemes led to the ass nment of configuration for each chirality center. 

A prioritization scheme is employed to heed risks with the greatest negative effect and the highest probability of occurrence. The objective of Risk Management is to balance the allocation of resources such that the minimum amount of resources maximizes the opportunity to eliminate or reduce risk to an acceptable level. 

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