Polyoxyethylene sorbitan

Adsorption of t-PA to process equipment surfaces consisting of either stainless steel or glass was minimized by adding the detergent polyoxyethylene sorbitan monooleate (Tween 80) to the semm-free culture conditioned media at 0.01% (vol/vol). The equipment was also rinsed, before use, with phosphate buffered saline (PBS) containing 0.01% Tween 80. Hydrophilic, plastic equipment was used whenever possible. AH buffers were sterile filtered. Sterile filtration of Hquids and gases is usually carried out using 0.2 or 0.45 p.m filters. 

Polysorha.tes. Polyoxyethylene sorbitan esters [9005-63-4] are formed from the reaction of sorbitol esters with ethylene oxide. These emulsifiers are almost always employed in combination with sorbitan esters and are used in the same appHcations (36). 

An oral dental riase geaeraHy coasists of water, alcohol, a humectant, an emulsifier, flavor, color, and an active agent. Water is the primary vehicle. The alcohol provides bite and is also a formulation aid. The humectant improves the feel ia the mouth and also prevents locking of the cap to the container between uses glycerin or noncrystaUiziag sorbitol may be satisfactory. The emulsifier is a nonionic type, for example, a polyoxyethylene—polyoxypropylene block copolymer or a polyoxyethylene sorbitan fatty acid ester. Flavors are generally a type of mint or cinnamon. Colors are FD C or D C. 

Essentially, Tri-Act corrosion inhibitors are based on various combinations and ratios of different sorbitan fatty acid esters (e.g., sorbitan tristearate) and polyoxyethylene sorbitan fatty acid esters (e.g., POE... 

Polyoxyethylene sorbitan monooleate (x)-sorbitan mono-9-octade-cenoate poly(oxy-l,2-ethanediyl)... 

Even entrapment of entire cells within reversed micelles without loss of their functionality has been achieved. For example, mitochondria and bacteria (Actinobacter cal-coaceticus, Escherichia coli, Corynebacterium equi) have been successfully solubilized in a microemulsion consisting of isopropyl pahnitate, polyoxyethylene sorbitan trioleate [162], Enhanced hydrogen photoproduction by the bacterium Rhodopseudomonas sphaeroides or by the coupled system Halobacterium halobium and chloroplasts organelles entrapped inside the aqueous core of reversed micelles with respect to the same cells suspended in normal aqueous medium has been reported [183,184],... 

The stability characteristics of two different antiperspirant lotion systems were compared. Sample 1 represented an aqueous emulsion containing an aluminum salt. The internal phase consisted of stearyl alcohol and ethylene oxide reaction products, polyoxyethylene sorbitan monostearate and polyoxyethylene sorbitan tristearate. Methylcellulose was used as a stabilizer and bodying agent. Sample 2 represented a dispersion of magnesium aluminum silicate in an aqueous system containing aluminum ions. Because of its com-... 

In the first example, procaine penicillin, an aqueous vehicle containing the soluble components (such as lecithin, sodium citrate, povidone, and polyoxyethylene sorbitan monooleate) is filtered through a 0.22 pm membrane filter, heat sterilized, and transferred into a presterilized mixing-filling tank. The sterile antibiotic powder, which has previously been produced by freeze-drying, sterile crystallization, or spray-drying, is aseptically added to the sterile solution while mixing. After all tests have been completed on the bulk formulation, it is aseptically filled. 

D Polyoxyethylene carbohydrate-20 Fatty alkylester D1 Polyoxyethylene sorbitan monolaurate, TWEEN... 

E 434 Polyoxyethylene sorbitan monopahnitate (polysorbate 40) E 435 Polyoxyethylene sorbitan monostearate (polysorbate 60)... 

Emulsifier 433 Polyoxyethylene sorbitan monooleate monolaurate 10 7th Series 281, p 140, 1964... 

The most common surfactants for analytical applications are nonionic (polyoxyethylene glycol monoethers, polyoxyethylene methyl- -alkyl ethers, t-octylphenoxy polyoxyethylene ethers, and polyoxyethylene sorbitan esters... 

Polyoxyethylene sorbitan trioleate (Tween 85) sugar ester (DK-F-110) tetraoxyethylene monodecyl ether (C10E4) polyoxyethylene-p-f-octyl phenol (Triton X-100) pentaethylene glycol dodecyl ether... 

Polysorbates (polyoxyethylene sorbitan fatty acid esters, refer to Fig. 3) are a mixture of molecules of varying sizes rather than a uniform mixture of a single chemical entity. All four official polysorbates (numbers 20,40, 60, and 80), listed in U.S. Pharma-copeia/National Formulary (USP/NF), contain 20 moles of oxyethylene. Polysorbates... 

Egelrud and Olivecrona (1973) studied the catalytic activity against several substrates of bovine milk enzyme preparations that had been purified about 7000-fold to a purity higher than 80% (Egelrud and Olivecrona 1972). The enzyme catalyzed the hydrolysis of emulsified trioleate, trioctanoate, monooleate, Tween 20 (polyoxyethylene sorbitan monolaurate), and p-nitrophenyl acetate. It was concluded that the enzyme had rather low substrate specificity and that the presence of activating serum factors is not needed for catalysis to occur. 

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