Sensation pleasant

The sensation of pleasant is postulated on the basis of cat neurophysiology and human psychophysics. The pleasant sensation is assumed to arise from the stimulation of a. small fiber geniculate ganglion system. The stimuli eliciting the pleasant sensation are lactones and other carbon-oxygen compounds (23). 

The general indistinctness of the pleasant sensation is assumed to be associated with the activation of extremely small fiber systems. 

As indicated elsewhere, there is evidence for a possible correlate of a pleasant sensation in a cat unit group, but this system has been little investigated in either the cat or in other species. Although the goat has a system that responds maximally to Na and Li salts, this system has not been seen in the carnivore. The chemical stimuli eliciting the human sensation of salty are salts in relatively high concentration, concentrations that in other species may stimulate more than one group. 

Both words and molecules can have a strong impact on our life. Both the word rose and the molecule responsible for the perfume of a rose give us a pleasant sensation. Words and molecules can be sweet, bitter, light, heavy, sour, cutting. There are words and molecules that can save or kill a life. 

Met-enkephalin and leu-enkephalin belong to a group of peptides called the opioid peptides, found predominantly in nerve tissue cells. Opioid peptides are molecules that relieve pain (a protective mechanism in animals that warns of tissue damage) and produce pleasant sensations. They were discovered after researchers suspected that the physiological effects of opiate drugs such as morphine resulted from their binding to nerve cell receptors for endogenous molecules. Leu-enkephalin and met-enkephalin are pentapeptides that differ only in their C-terminal amino acid residues. Substance P and bradykinin stimulate the perception of pain, an effect opposed by the opioid peptides. 

The author also observes that coffee, unlike hard liquor or narcotics which intoxicate and numb the senses, appears to combine the pleasant sensations of the two kinds while stimulating the intelligence instead of dulling it. Economic considerations reappear in the conclusions to this study ... 

There is this, too, that the liquids of honey and milk give a pleasant sensation of the tongue, when rolled in the mouth but on the other hand the loathsome nature of wormwood and biting centaury set the mouth awry by their noisome taste so that you may easily know that those things which can touch the senses pleasantly are made of smooth and roimd bodies, but that on the other hand all things which seem to be bitter and harsh, these are held together with particles more hooked . 

Recent work has tended to confirm this general picture. Maranetra and Pain (36 ) compared tilidine and morphine and found that tilidine caused less respiratory depression. They did report, however, that the majority of subjects noted a pleasant sensation of light-headedness and sleepiness on the 3 occasions when the the drug was administered. Tammisto and Tiger-stedt (58 ) studied the interaction of tilidine and pethidine in post-operative pain. Respiratory depression and sedation were more evident after pethidine alone, other side effects after pethidine-tilidine combinations. 

Four characteristics of odor are subject to measurement by sensory techniques intensity, detectability, character (quality), and hedonic tone (pleasantness-unpleasantness) (16). Odor intensity is the magnitude of the perceived sensation and is classified by a descriptive scale, e.g., faint-moderate-strong, or a 1-10 numerical scale. The detectability of an odor or threshold limit is not an absolute level but depends on how the odorant is present, e.g., alone or in a mixture. Odor character or qualit) is the characteristic which permits its description or classification by comparison to other odors, i.e., sweet or sour, or like that of a skunk. The last characteristic is the hedonic type, which refers to the acceptability of an odorant. For the infrequent visitor, the smell of a large commercial bread bakery may be of high intensity but pleasant. For the nearby resident, the smell may be less acceptable. 

In humans, a comparative examination of the positive reinforcing effects of solvents showed that among inhalant-dependent subjects, solvents induced a more intense sensation of pleasant feelings than that induced by alcohol and nicotine in subjects addicted to these substances (Kono et al. 2001). Solvent-dependent subjects reported pleasant feelings comparable to those reported by stimulant-dependent subjects after use of methamphetamine. However,... 

Mood lift Relaxation Creative thinking Heightened sensations Pleasant body feelings Pain relief Reduced nausea... 

This refers to any of the sensations we localize in our skin and describe as being either pleasant or unpleasant pain, itching, tickling, hot, cold, softness, smoothness, etc. 

The toxins affect the central nervous system (CNS). Symptoms start within twenty minutes and may last for two to four hours, but peak hallucinogenic activity rarely lasts for more than one hour. Symptoms include anxiety and tension, visual effects such as blurring, euphoria, increased color perception with closed eyes, but also headache and fatigue. The overall sensation is usually described as pleasant. 

Occurrence.— If red ants be made to pass over blue litmus paper and be at the same time irritated, they leaveared streak behind them, produced by the formic acid which they qect. By placing the hand on an ant hill, a tingling sensation is felt from the same cause, and the hand acquires the powerful and pleasant odour of formic acid. 

Typically, patients or intravenous drug users who receive intravenous morphine experience a pleasant floating sensation with lessened anxiety and distress. However, dysphoria, an unpleasant state characterized by restlessness and malaise, may sometimes occur. 

The /Invar of an edible substance is the combined sensation of taste and odor as perceived by the eater/drinkcr of that substance. Although the components Jlufood substances, the full aspects of flavor require intimate contact between substance and consumer. The odors emanating from a bakery tend to be richer and more pleasant than the bread itself the flavor of coffee seldom attains the richness of aroma lhat one perceives in the vicinity of a coffee roasting plant. Flavor is a unique combination of nerve impulses on the brain centers as the result of actions upon receptors located on the longue and in the lining of [he nose. II is thus the result of interaction between the food substance and the consumer. 

Visualize This is a different exercise from your graduate school visualization. In this one, you imagine yourself in a favorite place, a place you find especially soothing and pleasant. It could be a real place or one found only in your imagination. Focus on the sensations of your special place—what does it feel like, look like, sound like You want to feel like you are really there. Take a few minutes to just relax in this place. It s there for you any time you need it, and it will always help you be calm and focused. 

Piperazines like BZP and TFMPP stimulate the brain, resulting in sensations and experiences which may be pleasant or unpleasant, frightening, dangerous, or lethal. Animal research has shown that BZP triggers the release of neurotransmitters called dopamine and norepinephrine, while TFMPP acts by stimulating nerve... 

Carbon disulfide (CS2) is a highly flammable, volatile, and extremely foulsmelling liquid that causes a burning sensation on the skin. It can produce psychic and visual disturbances as well as nausea, vomiting, and convulsions. Typically carbon disulfide is used as a solvent for substances such as sulfur or phosphorus. There are other solvents (the methylene halides or the xylenes, for example) that would be more pleasant to work with and much less hazardous. 

Effects Overwhelming psychedelic effects occur almost instantly, softening to a pleasant LSD-like sensation after 2-3 minutes. Changes in perception may occur including brightening of colors and macroscopia (size changes). Total experience last 20-30 minutes. 

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