Pesticides assessment

Pesticide Assessment Guidelines, Data Requirements Subdivision D, Product Chemistry E, Ha ard Evaluation—Wildlife and Aquatic Organisms F, Ha ard Evaluation—Human and Domestic Animals G, Product Peformance H, Eabeling , Experimental Use Permits J, Ha ard Evaluation—Nontafget Plants K,... 

Pesticide Assessment Guidelines, Subdivision U, Applicator Exposure Monitoring, U.S. Environmental Protection Agency, Washington, D.C., 1986. 

Environmental Protection Agency (1991). Pesticide Assessment Guidelines Subdivision F, Hazard Evaluation Human and Domestic Animals. Addendum 10, Neurotoxicity Series... 

An important question when planning a probabilistic assessment is whether to separate variability and uncertainty in the analysis and results. This is one of the key issues that were given special consideration at the Pellston workshop that developed this book. While there was not a consensus, the majority view was that there are potential advantages to separating variability and uncertainty, but further case studies are needed to evalnate the benehts and practicality of this for routine pesticide assessment. 

Currently, approaches that separate variability and uncertainty have rarely been used for pesticide assessments, so further evaluation is needed to determine whether they are unsuitable for other reasons (e.g., complexity or cost). Also, it can be difficult to separate variability and uncertainty in real datasets, so the development of guidance on this would be helpful. 

Methods for evaluating the performance and utility of uncertainty analysis in the context of probabilistic pesticide assessments are needed. This should include comparisons between assessment outputs and existing field data (e.g., avian field studies) to evaluate whether decision makers can rely on the assessment methods. Consideration should also be given to existing field data to refine generic assessment models, using Bayesian updating methods. 

Schmitt, R.D. Pesticide Assessment Guidelines Subdivision 0 Residue Chemistry, U.S. Environmental Protection Agency Washington, DC, 1982. 

Farber, T.M. (1987). Pesticide assessment guidelines, subdivision F, position document Selection of a maximum tolerated dose (MTD) in oncogenicity studies. Toxicology Branch, Hazard Evaluation Division, Office of Pesticides Programs, USEPA. NTIS PB88-116736. 

USEPA (1987). Pesticide Assessment Guidelines, Subdivision U, Applicator Exposure Monitoring, Report No. 540/9-87-127, Office of Prevention, Pesticides and Toxic Substances, Washington, DC, USA (website http //www.epa.gov/pesticides). 

EPA-FIFRA, 1982. The Federal Insecticide, Fungicide and Rodenticide Act. Pesticide Assessment Guidelines, subdivision N chemistry Environmental fate, and subdivision E, J L Hazard Evaluation. Office of Pesticide Programs. US Environmental Protection Agency, Washington D.C. (1982 and updates). ONLINE information regarding the latest updates of these test guidelines US National Technical Information System... 

Lu FC (1995) A review of the acceptable daily intakes of pesticides assessed by the World Health Organization. Regulatory Toxicology and Pharmacology 21 351-364. 

Pesticide assessment guidelines under the Federal Insecticide, Fungicide, and Rodenticide Act stipulate that organophosphates proposed for use as insecticides be tested both for their capability to cause acute toxicities due to inhibition of acetylcholinesterase and for their potential to cause inhibition of neurotoxic esterase and subsequent delayed neuropathy. Testing could be performed in laboratory rodents because they, like all species, are susceptible to acetylcholinesterase inhibition, but rodents do not develop notable ataxia, and neuropathological... 

Sears M, Walker CR, van der Jagt RHC, Claman P. Pesticide assessment Protecting public health on the home turf. Pediatr Child Health 2006 11 (4) 229 34. 

Pesticide Assessment Guidelines, Subdivision F Hazard Evaluation Human and Domestic Animals", Office of Pesticide Programs, Environmental Protection Agency, 1982. 

Environmental protection Agency (EPA) Pesticide assessment Guidelines, Subdivision E. Hazard Evaluation Human and domestic Animals. Addendum 10 Neurotoxicity, Series 81, 82, and 83. National Technical Information Service, Springfield, VA, 1991. 

Chemistry Environmental Fate" Pesticide Assessment Guidelines Subdivision N, EPA, 83-153973, NTIS, October,... 

Hazard Evaluation Wildlife and Aquatic Organisms PB" Pesticide Assessment Guidelines Subdivision E, EPA, 83-153908 NTIS, October, 1982. 

Oncogenicity (or carcinogenicity) testing is one of the specific testing areas under Subdivision F of the Pesticide Assessment Guidelines Hazard Evaluation for Humans and... 

U.S. EPA. 1984. Pesticide assessment guidelines. Subdivision E, hazard evaluation Human and domestic animals. 1991. Pesticide assessment guidelines. Subdivision F, addendum 10. Neurotoxicity series 81, 82, and 83. 

U.S. EPA, 1983. Pesticide Assessment Guidelines, Subdivision M - Biorational Pesticides, National Technical Itiformation Service, Springfield, VA, PB83-153965. 

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