Oxacillin resistant

Oxacillin-resistant S. aureus, Pseudomonas aeruginosa, Acinetobacter spp., Enterobacter spp., and Klebsiella pneumoniae... 

FCC,b c trimethoprim-sulfamethoxazole, clindamycin ampidllin-sulbadam, or amoxidllinresistant Vancomycin (gentamicin or rifampin)... 

Oxacillin-resistant strains Vancomycin6 doses Pediatic dose cefazolin 100 mg/kg per 24 hours IV in three equally divided doses gentamicin 3 mg/kg per 24 hours IV/ IM in three equally divided doses 30 mg/kg per 24 hours IV in two equally divided doses 6 weeks IB Adjust vancomycin dosage to achieve 1 -hour serum concentration of... 

Thomson KS, Moland ES. (2004) CS-023 (R-115685), a novel carbapenem with enhanced in vitro activity against oxacillin-resistant Staphylococci and Pseudomonas aeruginosa. J Antimicrob Chemother 54 557-562. 

Gram-positive Gram-negative MRSA, methicillin-resistant Staphylococcus aureus, ORSA, oxacillin- resistant Staphylococcus aureus, GAR, garenoxacin CIP, ciprofloxacin LVX, levofloxacin GAT, gatifloxacin MXF, moxifloxacin GEM, gemifloxacin. 

An 85-year-old woman with an oxacillin-resistant Staphylococcus aureus infection took oral linezolid... 

The prototypical lantibiotic, nisin, was discovered in 1928 for its antibacterial properties and has been used as a preservative in dairy products since the 1950s (1). Nisin and other lantibiotics exhibit nanomolar efficacy against many Gram-positive strains of bacteria (2), which include methicillin resistant Staphylococcus aureus, vancomycin resistant enterococci, and oxacillin resistant bacteria. On the other hand, some lantibiotics function as morphogenetic peptides rather than antibiotics and are important for spore formation in streptomycetes (3). Since the structural elucidation of nisin in the early 1970s, extensive research efforts have been directed at understanding the biosynthesis and mode of action of various lantibiotics. 

Liu CP, Lee CM, Su SC, Li YT. Susceptibility testing and clinical effect of fusidic acid in oxacillin-resistant Staphylococcus aureus infections. J Microbiol Immunol Infect 1999 32(3) 194-8. 

In 76 patients receiving long-term teicoplanin for chronic osteomyelitis due to oxacillin-resistant Staphylococcus aureus, teicoplanin had to be withdrawn in only one subject because of low-grade fever, muscular pain, and sleeplessness these adverse effects abated after withdrawal (4). 

Testore GP, Uccella I, Sarrecchia C, Mattei A, Impagliazzo A, Sordillo P, Andreoni M. Long-term intramuscular teicoplanin treatment of chronic osteomyelitis due to oxacillin-resistant Staphylococcus aureus in outpatients. J Chemother 2000 12(5) 412-15. 

The most relevant of the coagulase-positive species is Staphylococcus aureus subsp. aureus (further S. aureus), pathogenic to both humans and animals. It is an extraordinary versatile pathogen and the major causative agent of numerous hospital-and community acqnired infections. The spread, survival and prevalence of antibiotic resistant clones of S. aureus are immensely important problems for human health. Major antibiotic resistance problems are typically associated with methicillin (oxacillin) resistant S. aureus strains (MRSA) and, more recently, vancomycin-intermediate (VISA) and vancomycin-resistant (VRSA) strains. Up to 30% of the hnman population carries S. aureus without any symptoms. In most cases, however, the colonizing strain serves as an endogenous reservoir for clinical infections (von Eiff et al. 2004). The disease spectrum includes abscesses, bacteremia, central nervons... 

Despite having the same spectram of action as that of other natural macrolides, ketolides have better in vitro activity against streptococci and other gram-positive microorganisms, including oxacillin-resistant Staphylococcus spp. and vancomycin-resistant enterococci [204-206], because a remarkable decrease takes place in the water solubility of those ketolides (Table I). 

A. (2004) A comparative evaluation of phenotypic and molecular methods for the detection of oxacillin resistance in coagulase-negative staphylococci. /. Infect. 

---