The penicillinase-resistant penicillins are oxacillin, cloxacillin, dicloxacillin, methicillin, and nafcillin

FIGURE 74 The penicillinase-resistant penicillins are oxacillin, cloxacillin, dicloxacillin, methicillin, and nafcillin. These agents are the drugs of 

Oxamniquine, a tetrahydroquinolone with antihelmintic properties, is used in schistosomiasis caused by Schistosoma mansoni. 

Oxamniquine, which is absorbed following oral administration, is very effective only in Schistosoma mansoni. Following treatment, the S. mansoni shifts from the mesenteric veins to the liver, where it is destroyed. The male S. mansoni is more susceptible to this killing effect than the female, but this will prevent the production of eggs at any rate. 

Several strategies to treat alcoholic liver disease have been evaluated. Prednisolone may improve survival in patients with hepatic encephalopathy. Nutrients such as S-adenosylmethionine and polyunsaturated lecithin have been found to have beneficial effects in nonhuman primates and are undergoing clinical trials. Other medications that have been tested include oxandrolone, propylthiouracil, and colchicine. At present, however, none of these drugs is approved for use in the United States for the treatment of alcoholic liver disease. The current 

Oxaprozin is a nonsteroidal antiinflammatory drug (NS AID) that decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis. It is indicated in the relief of symptoms of rheumatoid arthritis and osteoarthritis. 

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