Morphological alteration

The normal rat kidney (NRK) cell line is an untransformed cell line established from rat kidney cells. However, when NRK cells are treated with both TGF alpha and TGF beta, the cells assume a transformed phenotype. In addition to exhibiting an altered morphology in monolayer culture, NRK cells possess the capacity for anchorage-independent growth while being treated with both TGF alpha and TGF... 

Variation of the deposition zone temperature affected the film stoichiometry and crystalline structure while not significantly affecting the deposition rate. A deposition zone temperature was optimized at 395 °C to produce (112)-oriented films without any detectable secondary phases. The susceptor location within the furnace did not affect the stoichiometry of deposited films, but it did alter morphology. Moving the susceptor toward the evaporation zone... 

A woman 7 months pregnant with her first child develops anemia. Laboratory evaluation indicates an increased mean cell volume (MVC), hypeisegmented neutrophils, and altered morphology of several other cell types. The most likely underlying cause of this woman s... 

The innermost layer of the epidermis, the stratum basale, consists of a single layer of columnar-shaped, undifferentiated stem cells. Mitosis of these cells constantly renews the epidermis and this proliferation compensates for the loss of dead stratum corneum cells (corneocytes) from the skin surface. As the cells produced by the basal layer move upward, they alter morphologically as well as histochemically to form the outermost layer, the stratum corneum. Over a 4- to 5-week period the entire epidermis is renewed [5]. 

Haskin, C. and Cameron, I. (1993) Physiological levels of hydrostatic pressure alter morphology and organization of cytoskeletal and adhesion proteins in MG-63 osteosarcoma cells. Biochemical Cell Biology 71 27-35... 

Keller, R., Brearley, C., Trethewey, R., and Muller-Rober, B., 1998, Reduced inositol content and altered morphology in transgenic potato plants inhibited for 1 D-myo-inositol 3-phosphate synthase. Plant J. 16 403 110. 

However, the isolated cells may develop altered morphology, functions, and have different levels of cell-cell interaction and usually also a dramatically decreased metabolism that could result in an altered response to test chemicals when compared to the in vivo situation [34], Furthermore, primary neuronal cultures consist predominantly of postmitotic neurons which do not proliferate, giving the model stability but also a limited life span. Consequently, the cultures always need to be freshly isolated and may not be fully suitable for high-throughput screening. Neuronal and glial primary cultures from the PNS and CNS can be derived from... 

Examples, which have in parts already been explicitly mentioned, are defects, such as marks of processing equipment on polymer films, filler particles that were removed from the polymer matrix, irregular ordering and pinholes in latex assemblies, or altered morphologies due to mechanical deformation and concentration of stresses, among others. 

Much of the chemical behavior of cellulose fiber can be attributed to cellulose structure. Since cellulose is a highly crystalline polymer, it can absorb mechanical energy efficiently for mechanical stress reaction ( 5, 19). The mechanically activated thermal energy, in addition to rupture of main chains, may alter morphology or microstructure of cotton cellulose. Accordingly, the crystallinity and accessibility of cotton fiber may be influenced. 

Maltese, W. A. Sheridan, K. M. (1987). Isoprenylated proteins in cultured cells subcellular distribution and changes related to altered morphology and growth arrest induced by mevalonate deprivation. J. Cell Physiol. 133,471-481. 

Figure 4.18. Stress-strain curve for SBS block copolymer (Kraton 101) deposited from solution (90/10 THF/MEK). Note behavioral changes brought about by altered morphology. (Beecher et al, 1969.)...

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