Oil-macerated garlic

A number of studies have focused on identifying the active antimicrobial principles in fresh garlic extract. Allicin has been identified as the active agent in garlic extracts. The antifungal activity of allicin has been shown to depend on the sulfhydryl moiety because activity is destroyed by thiols such as L-cysteine, glutathione, and mercaptoethanol. Ajoene, a compound found in oil-macerated garlic, has also been shown to have antimicrobial activity (Ali et al., 2000). 

Yoshida H, Iwata N, Katsuzaki H et al (1998) Antimicrobial activity of a compound isolated from an oil-macerated garlic extract. Biosd Biotechnol Biochem 62(5) 1014-1017... 

Yoshida H, Katsuzaki H, Ohta R et al (1999) An organosulfur compound isolated from oil-macerated garlic extract, and its antimicrobial effect. Biosci Biotechnol Biochem 63(3) 588-590... 

Teas, leaf essential oil, leaf oleoresin, eugenol, bark essential oil bark oleoresin, E-cinnamaldehyde, oil-macerated garlic extract, tannins, polymers of flavanols, cassia bark-derived substances, crude extracts of bulbs (Lycoiis chinensis), stems and leaves of (Nandina domestica), (Mahonia fortune ), (Mahonia bealei), stems of Berbeiis thunbergii and stems, leaves and fruits of Camptotheca acuminata, methanol and acetone extracts of 14 plants belonging to different families, Eruca sativa (aerial and root). EOs and methanol extracts of sweet basil Ocimum basilicum L. (Lamiaceae). Ponkan (Citrus mticulata Blanco). Seeds of Zizyphus jujube. 

Garlic supplements - powder tablets or capsules, steam-distilled oil, vegetable oil macerate extract, or extract aged in dilute alcohol - are widely available and are taken by millions. Since the active principle, allicin, is not present in garlic bulb, the supplements rely on the presence of precursor alliin and enzyme alliinase. In tests on 24 commercial brands of enteric-coated tablets, all except one gave low dissolution allicin release 83% of the brands released less than 15% of their potential allicin.78,79 Relevant factors were impaired enzyme activity caused by excipients and slow tablet disintegration. Caveat emptor ... 

One-a-Day Garlic, 600-mg odor-free softgel, concentrated oil macerate... 

The oil of ether-extracted garlic homogenate has a similar qualitative composition to the oil-macerates, but it has a major advantage in being highly concentrated. It contains up to nine times the amount of the vinyl dithiins and allyl sulfides and four times the amount of the ajoenes found in typical commercial oil-macerates (Lawson, 1993). 

Nature s Resource Garlic Cloves, 580 -mg capsules One-a-Day Garlic Oil macerate, 600-mg softgel Sundown Herbals Odor-Free Garlic, 400-mg tablets Sundown Herbals Odorless Garlic, 300 mg Sun Source Garlique , 400-mg tablets... 

Steam distillation of garlic produces an oil that also has several different allyl sulfur constituents such garlic oils can contain about diallyl disulfide (DADS, -26%), diallyl trisulfide (DATS, 19%), allyl methyl trisulfide (15%), allyl methyl disulfide (13%), diallyl tetrasulfide (8%), allyl methyl tetrasulfide (6%), dimethyl pentasulfide (4%), dimethyl trisulfide (3%), and dimethyl hexasulfide (1%). The oil derived from macerated garlic contains vinyldithiins and ajoenes. Storage of garlic in ethanol for several months... 

Garlic oil macerate oil DAS, allyl methyl dimethyl, mono-to hexasulfides, allyl 1 -propenyl and methyl 1 -propenyl di-, tri-, and tetrasulfides Cold extraction method (maceration) and steam distillation Manufactured as capsule in diluted form for therapeutic use... 

Ajoene was discovered as the most potent platelet inhibitor from an oil-macerated crushed garlic (Apitz-Castro et al 1983), and they revealed that ajoene inhibited both of the arachidonate metabolism and the membrane G-protein level signal transduction of platelets (Apitz-Castro eta/. 1986a, 1986b, 1988). 

When garlic cloves are minced or macerated in vegetable oil, allicin transformation compounds are mainly vinyldithiins and ajoenes with little allyl sulfides. These compounds remain stable in the oil for at least 3 years, the vinyldithiins being considerably more stable than the ajoenes. Refrigeration of these oils prolong the lifetime of the ajoene content [49]. 

Raw Garlic FD - Garlic Garlic Oil oiF Macerate Soaking (AGE)" Heating ... 

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