Octyl alcohol

Boiling range, below 160 C above 192 C None None Solubility in water at 20 C Solubility of water in, at 20 C 0.10% by wt 2.6% by wt 

Constant-boiling mixture. b.p. 99.1 C Unsaturates, as ethyl hexanol 0.2% max. 

Flash point, Open cup Freezing point 185T -70 C aeta to glaaa Weight per gallon at 20 C 6.94 lbs 

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RESOLUTION OF sec.-OCTYL ALCOHOL (d/-2-OCTA-NOL) INTO ITS OPTICALLY ACTIVE COMPONENTS (d- AND f-2-OCTANOL)... 

MC.-Octyl alcohol methyl n-hexyl carbinol CH3CH(OH)(CHj)jCH3 = CgH,OH is converted by heating with phthalic anhydride into sec.-octyl hydrogen phthalate ... 

The latter upon decomposition with dilute hydrochloric acid yields laevo sec.-octyl hydrogen phthalate the crystalline brucine salt, when similarly treated, affords the dextro sec.-octyl hydrogen phthalate. These are reerystallised and separately hydrolysed with sodium hydroxide solution to yield pure I- and d-sec.-octyl alcohols ... 

To obtain optically pure I- and daec.-octyl alcohols, steam distil the respective esters with 30 per cent, sodium hydroxide solution use the proportions 1 mol of ester to 2 mols of sodium hydroxide. Separate the alcohols from the steam distillate, dry over anhydrous potassium carbonate, and distil under diminished pressure. Both samples boU at 86°/20 mm. (9) and have the following rotations ... 

This is due to methyl n-hexyl ketone in the original aec.-octyl alcohol it is most easily separated by steam distillation as described. 

Table 4 lists a variety of aLkoxypropionaldehydes and certain of thek properties (67). Alcohols up to -butyl have been added to acroleki ki this fashion. Methyl, ethyl, and aHyl alcohols react with ease, while the addition of hexyl or octyl alcohol proceeds ki low yields. Although the aLkoxypropionaldehydes have found only limited kidustrial utiUty, it is anticipated that they will find use as replacements for more toxic solvents. Furthermore, the aLkoxypropionaldehydes may readily be reduced to the corresponding alkoxypropanols, which may also have deskable properties as solvents. 

The cosolvents are a mixture of ethanol, propyl, butyl and higher alcohols up to octyl alcohol. Corrosion inhibitor is also requited. 

Docusate Calcium. Dioctyl calcium sulfosuccinate [128-49-4] (calcium salt of l,4-bis(2-ethylhexyl)ester butanedioic acid) (11) is a white amorphous soHd having the characteristic odor of octyl alcohol. It is very slightly soluble in water, and very soluble in alcohol, polyethylene glycol 400, and com oil. It may be prepared directly from dioctyl sodium sulfo succinate dissolved in 2-propanol, by reaction with a methan olic solution of calcium chloride. 

Docusate Sodium. Aerosol OT, Colace, and Doxinate are trade names of docusate sodium [577-11-7] (dioctyl sodium sulfo succinate, sodium salt of l,4-bis(2-etliylhexyl)estet butanedioic). This white, wax-like, plastic sohd, with a characteristic odor suggestive of octyl alcohol, is usually available in the form of pellets. One gram of the sodium salt slowly dissolves in about 70 mL water. Docusate sodium is freely soluble in alcohol and glycerol, very... 

Alcohols, particularly ethanol [64-17-5] and 2-propanol [67-63-9] are important disinfectants and antiseptics. In the aUphatic series of straight-chain alcohols, the antimicrobial activity increases with increasing molecular weight up to a maximum, depending on the organism tested. For Staphylococcus aureus the maximum activity occurs using amyl alcohol [71-41-0], for Salmonella typhosa, octyl alcohol [111-87-5], CgH gO (43) ioT Mycobacterium tuberculosis... 

Alcohols Moderate- to high-molecular-weight monohydric and polyhydric alcohols octyl alcohol C-12 to C-20 alcohols laiiryl alcohol Distillation fermentation papermaking glues and adhesives... 

A. Preparation of Sec.-Oclyl Hydrogen Phihalate.—A mixture of 130 g. (i mole) of 5ec.-octyl alcohol (Org. Syn. 1, 61) and 148 g. (i mole) of phthalic anhydride is heated for twelve to fifteen hours in a flask surrounded by an oil bath at 110-115° (Note i). During the heating the mixture should be mechanically stirred... 

The octyl hydrogen phthalate is filtered, washed with water, ground thoroughly with water in a mortar and finally filtered and dried. For complete purification it may be crystallized either from petroleum ether (b.p. 60-70°) or glacial acetic acid from which it separates as needles melting at 55°. The crude material, however, is perfectly satisfactory for the following experiments. The yield is nearly quantitative if the ec.-octyl alcohol is pure (Note 2). 

Optically pure I- and d-sec.-octyl alcohols are obtained by distillation in a current of steam of the -octyl hydrogen phthalate and 2 moles of sodium hydroxide in 30 per cent solution. The alcohols are practically insoluble in water and are separated, dried with potassium carbonate and distilled. Each boils at 86 /20 mm. and has a rotation (0)5461-1-11.8°, (a) -1-9.9° ( )546i (0)0 9-9°- The yields of alcohol from the sec.-... 

The yield of sec. -octyl hydrogen phthalate from the crude sec.-octyl alcohol used in this preparation was 61-64 per cent. 

The resolution of sec.-octyl alcohol was first described by Pickard and Kenyon. The method employed by these authors differed from the foregoing in the following respects. The brucine salt of sec.-octyl hydrogen phthalate was crystallized several times from acetone until it reached optical purity and was then decom-... 

Chemical Designations - Synonyms Alcohol C-8 Heptylcarbinol 1-Octanol Octyl alcohol Chemical Formula CH3(CHi)sCHiOH. 

According CD Zincke," ii coutains octyl alcohol CaHj OH and its acetio ester C,, HO., aud capcoic ester According to Mos-... 

It contains the acetic and buiyric extort of hexyl nod octyl alcohols, and traces o( etby 1 hutyiaio,... 

The higher aliphatic alcohols, from octyl alcohol upwards, have-recently been introduced as perfume materials with considerable success. Only one or two of them, such as nonyl and undeeylenic alcohols, have so far been detected as natural constituents of essential oils, but other members of the series are prepared artificially, and are employed in minute quantities in the preparation of perfumes with characteristic, fruity bouquets. These alcohols are greatly diminished in perfume value by traces of impurities. According to H. J. Prins, the first interesting member of the series is octyl alcohol it has a very sweet, rose-like odour, and is especially suitable for giving a rose perfume that pecnliar sweet smell which distinguishes a rose from a rose perfume. This feature of the aliphatic alcohols diminishes in the series from Cg to Cjg. 

Octyl Alcohol.—This is the primary normal alcohol of the formula CH3(CH2)gCH20H. It has an odour recalling that of opoponax, and is useful in the blending of perfumes of this type. It boils at 196° to 197°, and has a specific gravity 0"8278. It yields octyl aldehyde on oxidation, whose naphtho-cinchoninic acid compound melts at 234°. 

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