Non-scheduled substances

Seizures of all of the substances in Tables I and II, with the exception of isosafrole and piperonal, both substances used in the illicit manufacture of MDMA (Ecstasy), have been reported for 2003 by 43 Governments, and seizures of 65 non-controlled chemicals have been reported by 22 Governments. As the information relating to non-controlled substances is essential to the revision of the adequacy and propriety of the current lists of substances in Tables I and II of the 1988 Convention, as well as to the maintenance of the limited international special surveillance list of non-scheduled substances, the Board encourages Governments to ensure that mechanisms are in place to record information on all chemicals found to be used in the illicit manufacture of drugs and not only those scheduled under the 1988 Convention. 

Having examined the results achieved during Operation Crystal Flow, the Board notes that increased monitoring of ephedrine and pseudoephedrine caused traffickers to obtain non-scheduled substances. Some of the non-scheduled substances were traded specifically to circumvent controls. The Board therefore urges competent authorities to establish adequate mechanisms for identifying suspicious transactions involving non-scheduled chemical substances. 

Related to the foregoing observations, the Board again recommends to all Governments that they should send pre-export notifications for shipments of pharmaceutical preparations containing ephedrines, control such preparations in the same way as they control the raw material and adopt adequate controls over the licit manufacture and distribution of precursors. The Board also draws the attention of competent authorities to the non-scheduled substances that traffickers search for when the monitoring of scheduled substances frequently used in illicit drug manufacture has been strengthened. 

The Board s responsibilities under article 12 of the 1988 Convention include assessing substances for possible inclusion in Table I or Table II of that Convention and reviewing the adequacy and propriety of those tables. In addition to those functions, the Economic and Social Council, in section I of its resolution 1996/29 of 24 July 1996, called upon the Board to establish a limited international special surveillance list of non-scheduled substances tor which substantial information existed of their use in illicit drug trafficking. 

Limited international special surveillance list of non-scheduled substances proposals for action by Governments... 

Following the establishment in 1988 of the limited international special surveillance list of non-scheduled substances, in accordance with Economic and Social Council resolution 1996/29, the Board has continued to closely monitor the illicit use of precursor chemicals that serve as substitutes for those that are more closely monitored under the 1988 Convention. In doing so, the Board has been able to ensure that the chemicals included in the limited international special surveillance list are those non-scheduled substances most likely to be diverted from legitimate trade. 

To perform that formal evaluation of the special surveillance list of non-scheduled substances, the advisory expert group of the Board reviewed seizure data for the five-year period 2000-2004. During that period, 44 countries reported seizing a total of 165 non-controlled substances, of which 23 were substances already included on the special surveillance list, 35 were on the reserve list and a further 29 substances met the criteria established by the Board for selecting substances for inclusion in the list. Those 87 substances were reviewed, which led to 36 substances being identified for inclusion in the limited international special surveillance list. 

The recommended series of action accompanying the special surveillance list of non-scheduled substances were found to be still valid. The Board emphasizes that the monitoring measures associated with the list should be applied through voluntary cooperation with the chemical industry, with no prescriptive regulatory requirement or sanction, in order to highlight the complementary need for more strict control of the substances listed in Tables I and II of the 1988 Convention. As in the past, the Board will continue to distribute the limited international special surveillance list directly to competent authorities. 

The Attorney General shall by regulation exclude any non-narcotic substance from a schedule if such substance may, under the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 301 et seq.), be lawfully sold over the counter without a prescription. 

The World Health Organization classified dextromethorphan as a non-analgesic, non-addictive substance in the late 1960s. In 1970, the Controlled Substance Act further added weight to this notion that dextromethorphan is not in the same class of drugs as its opiate forbearers in its abuse potential. This led to the decision of the DEA to leave dextromethorphan off its schedules of controlled substances. 

Use of any non-Schedule I drug or substance that is identified in the other schedules in 21 CFR 1308 except when the use is under the instructions of a licensed medical practitioner who is familiar with the driver s medical history and has advised the driver that the substance will not adversely affect the driver s ability to safely operate a commercial motor vehicle ... 

A driver cannot report for duty or remain on duty when expected to perform a safety-sensitive function when the driver uses any drug or substance identified in 21 CFR 1308.11 Schedrde I any amphetamine, narcotic, or other habit-forming drug, including marijuana any non-Schedule I drug or any substance that is identified in the other Schedules in 21 CFR 1308. 

Non-prescription cough medicines with codeine are Schedule V chugs, which have a low potential for abuse compared to Schedule IV drugs, an accepted medical use in the United States, and the likelihood of limited physical or psychological dependence if abused. Federal trafficking penalties for a first offense of a Schedule V substance is not more than one year and fines of up to 100,000 for individuals and 250,000 for organizations. A second offense carries a maximum of 30 years to life if a death is involved and fines up to two and 10 million dollars. 

Trainee health outcomes Number of medical procedures performed Educational performance in relation to on-call schedules (e.g., postcall vs. no call) National registry of resident motor vehicle crashes and relevant covariates (e.g., work schedules, distance driven, time of day, work-related and non-work-related exposure measures) Longitudinal database of resident health outcomes relative to an appropriate control group (e.g., dentist trainees) Health outcomes from a variety of domains, including mental health and substance use disorders, pregnancy, endocrine, cardiovascular, and neurological... 

Non-prescription goods (and those meeting the criteria for OTC status) are handled by the Chemical emd Non-Prescription Drug Branch (CNPDB). Applications to register new OTC medicines are handled by the Scheduling and Over-the-Counter Section, whereas applications for listable goods and those for new complementary medicines are hemdled by other sections within the same branch. Further details on specific products or substances are provided in Parts 2 and 3 of Schedule 10 of the Regulations. 

Transitional substances are those supplied in Canada at >20 kg a between 1 January 1987 (and hence which cannot be included in the DSL) and the date on which the New Substances Notification Regulations come into force. These substances have to be notified within 90 d with Schedule I data. If specified trigger supply quantities are exceeded during the transition period or the subsequent 5 years, the maximum additional supplement is with Schedule II data for chemicals, with deadlines dependent on the year in which the trigger quantity was exceeded. However, when a trigger quantity for a transitional chemical is exceeded after this 5-year period, the standard provisions for non-transitional chemicals apply. 

Storage tanks and delivery pipelines for purified water and water for injection shall be made out of non-toxic and anticorrosive substance, and pipelines shall be kept clear of places where water may remain stagnant. Their sterilization and cleaning schedules shall be defined. The pressure-relief outlet in the tank shall be protected by a non-fibre-releasing hydrophobic microbial air-filter. Water for injection shall be stored above 80°C or at constant circulation above 65°C, if necessary. 

A. One file for all Schedule II controlled substances, one file for Schedule III-V controlled substances, and one file for all non-controlled drug products dispense. 

Definitions for commercial purposes include those of the EC Combined (Tariff) Nomenclature, and the Tariff Schedules of the United States (Annotated Schedule 5 - Non-metallic Minerals and Products, Pt 2, Ceramic Products, Headnotes, 1976). The EINECS definition, aiming at defining existing substances in contrast to new ones, adopts an exhaustive listing approach. 

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