Central nervous system disorder

The effects of occupational exposure to lindane have been investigated extensively (96—100). These studies indicated that occupational exposure to lindane resulted in increased body burdens of this chemical however, toxic effects associated with these exposures were minimal and no central nervous system disorders were observed. This is in contrast to the polyneuropathies that are often observed after exposure to other haloorganic solvents. 

Alzheimer s disease in which the pathogenicity of amyloid peptides depends on proteases, namely secretases, involved in amyloid precursor protein (APP) maturation. This chapter will describe how the proteolysis of chemokines might participate in the neuropathogenesis of HIV infection, thus contributing to the development of the central nervous system disorder termed HIV-associated dementia (HAD). 

Demopoulos, H.B., Flam, E.S., Peitronigro, D.D. and Seligman, M. (1980). The free radical pathology and the micro-circulation in the major central nervous system disorders. Acta Physiol. Scand. 492, 91-119. 

Central nervous system disorder resulting in a decreased level of consciousness (see section on cognitive impairment)... 

It is unclear whether long-term copper poisoning exists in humans. Some have related certain central nervous system disorders, such as giddiness, loss of appetite, excessive perspiration, and... 

Bjorklund A, Lindvall O (2000) Cell replacement therapies for central nervous system disorders. Nat Neurosci 3 537-544... 

Epibatidine provides an attractive lead for the treatment of mainly central nervous system disorders such as Alzheimer s and Parkinson s diseases, dyskinesias,... 

A second-generation manufacturing process involving a highly enantio- and diastereo-selective lipase-catalysed kinetic resolution step has recently been reported for the production of pregabalin, a lipophilic y-aminobutyric acid analogue that was developed for the treatment of several central nervous system disorders (Scheme 1.32). ° ... 

Serum carnosinase activities in central nervous system disorders. Clin. Chim. Acta 225, 57-64. 

Anti-TNF therapy can give rise to serious reactions, including anaphylaxis, sometimes fatal blood disorders, tuberculosis and other infections, rare reports of lymphoma and solid tissue cancers, rare reports of serious liver injury, rare reports of drug induced lupus and rare reports of demyelinating central nervous system disorders, which prompted the FDA to change the respective labeling of these drugs. 

Ethanol (ethyl alcohol) has central nervous system depressant properties and is widely used to relieve anxiety and produce sedation. Although some medical practitioners occasionally prescribe an alcoholic beverage for relieving minor anxiety and inducing sleep, individuals frequently self-medicate with ethanol. Many individuals who abuse alcohol may have started using it to relieve symptoms of central nervous system disorders, such as anxiety and depression. 

CENTRAL NERVOUS SYSTEM DISORDERS Parkinson s Disease... 

Quinazolino-1,4-benzodiazepines are useful in the treatment of some central nervous system disorders [79GEP(0)2758875] and showed chole-cystokinin antagonist activity (85USP4554272, 85USP4559338). 

Clinical Pharmacology of the Muscarinic Receptor-Blocking Drugs Therapeutic Applications Central Nervous System Disorders Parkinson s Disease... 

Malik S, Boeve BF, Krahn LE, Silber MH (2001) Narcolepsy associated with other central nervous system disorders. Neurology 57 539-541... 

The ergot alkaloids have been associated with a number of spectacular outbreaks of central nervous system disorders, sometimes called ergotism. St. Anthony s fire is an example of convulsive... 

Neuroactive Steroids and Central Nervous System Disorders Mingde Wang, Torbjom Backstrom,... 

Not all drug effects on the central nervous system can be categorized as spellbinding, but all produce disability. Often the result is a worsening of the patient s overall condition, and sometimes the result is an extremely distressing or disabling psychiatric reaction. Ironically, psychiatric drugs do not cure or ameliorate central nervous system disorders they cause them. 

The analysis of cerebrospinal fluid (CSF) has been used as an aid in the diagnosis of central nervous system disorders, even though the composition... 

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