Muscle chilling

The most significant occupational exposures to zinc would occur during the smelting and refining of zinc ore. The standards for occupational exposure have been estabUshed at a level to prevent the onset of metal fume fever. This temporary condition is caused by excessive exposure to freshly formed fumes of zinc oxide and results in flulike symptoms of fever, chills, headache, muscle pain, nausea and vomiting. 

Influenza is an acute viral disease caused by Influenza A (sporadic, epidemic, and pandemic) or B (sporadic outbreaks) virus. Symptoms typically occur suddenly and include high fever, chills, headache, muscle aches, sore throat, and malaise. Serious complications can be caused by bacterial superinfection of the respiratory tract. 

Signs and symptoms resembling serum sickness-chills, fever, edema, joint and muscle pain, and malaise... 

Adverse Effects Adverse effects are common with the beta interferons (Table 26-3). Commonly, flulike symptoms consist of fever, fatigue, muscle aches, malaise, and chills. Symptoms begin a few hours after the injection and dissipate 8 to 24 hours later.38 Preventive measures can be employed (Table 26-4). In temperature-sensitive patients, beta interferon-induced fever... 

Myoclonic Single and very brief jerks of all major muscle groups. Patients with these may not lose consciousness, due to the seizure lasting less than 3 to 4 seconds. Patients may describe these seizures as shoulder shrugs or spinal chills. Myoclonic seizures may cluster and build into a generalized tonic-clonic seizure. 

Chills, diaphoresis, headache, anorexia, cough, weakness, sore throat, dizziness, and muscle pains are frequently present before the onset of fever. 

Malaria is transmitted by the bites of the Anopheles mosquitoes which introduce into the bloodstream one of four species of sporozoites of the plasmodia (Plasmodium falciparum, P. ovale, P. vivax or P. malariae). Initial symptoms of malaria are nonspecific and may resemble influenza and include chills, headache, fatigue, muscle pain, rigors, and nausea. The onset of the symptoms is between 1 to 3 weeks following exposure. Fever may appear 2 to 3 days after initial symptoms and may follow a pattern and occur every 2 or 3 days (P. vivax, P. ovale and P. malariae). Fever with P. falciparum can be erratic and may not follow specific patterns. It is not unusual for patients to have concomitant infections with P. vivax and P. falciparum. Falciparum malaria must always be regarded as a life-threatening medical emergency. 

Signs and Symptoms Are nonspecific and consist of irregular fever, headache, profound weakness and fatigue, chills and sweating, generalized severe joint and muscle pain (myalgia), anorexia, weight loss, and depression. Joint complications are common. 

Signs and Symptoms Diagnosis of psittacosis can be difficult. There is a variable clinical presentation but may include fever, headache, muscle pain (myalgia), chills and upper or lower respiratory tract disease, and dry cough. Pneumonia is often evident in chest x-rays. 

Signs and Symptoms Initial symptoms are flu-like with abrupt onset of high fever, severe frontal headache, chills, muscle pain (myalgia), pain behind the eyes, nausea, and vomiting. Additional symptoms may include sensitivity to light (photophobia), diarrhea, and sore throat. Fever may be biphasic. CNS symptoms range from drowsiness to disorientation, convulsions, paralysis, coma, and death. May cause abortions or CNS malformations in the fetus. 

Signs and Symptoms Sudden onset of high-grade fever, sore throat, chills, headaches, neck stiffness, muscle pain (myalgia), and sensitivity to light (photophobia). Lesions appear in the throat and mouth, and on the palms and soles of the feet. Lymph nodes near the site of the bite may be enlarged. 

MDMA stimulates the CNS, causes euphoria and relaxation, and produces a mild hallucinogenic effect. It can cause muscle tension, nausea, faintness, chills, sweating, panic, anxiety, depression, hallucinations, and paranoid thinking. It increases heart rate and blood pressure and destroys serotonin (5-HT)-producing neurons in animals. It is considered to be neurotoxic in humans. 

Symptoms Symptoms appear about ten to twenty days after the Q fever rickettsia are inhaled. The symptoms resemble flu symptoms and include fever, chills, headache, fatigue and muscle aches. About one half of persons with symptoms will have pneumonia evident on chest X-ray and some of these will have a cough or chest pain. The complications of meningitis or and inflammation of the heart may arise, but these are uncommon. Normally, the duration of Q fever is two days to two weeks at which time the disease resolves without permanent effects on the individual. 

Signs and Symptoms From three to six hours after aerosol exposure, sudden onset of chills, fever, headache, pain in one of more muscles, and nonproductive cough. Some patients may develop shortness of breath and retrostenal (situated or occurring behind the sternum) chest pain. Fever may last two to five days, and cough may persist for up to four weeks. Patients may also experience nausea, vomiting, and diarrhea if they swallow toxin. Higher exposure levels can lead to septic shock and death. 

Symptoms Ulceroglandular disease involves a necrotic, tender ulcer at the site of inoculation, along with tender, enlarged regional lymph nodes. Fever, chills, headache, and malaise often accompany such symptoms. Systemic and pneumonic forms usually involve serious unproductive cough, abdominal pain, generalized muscle pain as well as prolonged fever, chills, and headache. 

Typical MEE, a 24- to 48-hour illness characterized by chills, fever, aching muscles, dryness in the mouth and throat, and headache, has been reported in several workers exposed to copper fume. With MEE, leukocytosis is usually present with counts of 12,000-lb,000/mm recovery is usually rapid, and there are no sequelae." Most workers develop an immunity to these attacks, but it is quickly lost, and attacks tend to be more severe on the first day of the workweek." ... 

The third condition, late respiratory systemic syndrome, is characterized by cough, mucus production, occasional wheezing, and systemic symptoms of malaise, chills, fever, and aching muscles and joints, occurring 4—12 hours alter exposure. This syndrome also has been termed TMA flu and clinically resembles hypersensitivity pneumonitis with visible chest X-ray infiltrates. High levels of IgG serum antibody and total serum antibody directed against trimellityl-human protein conjugates accompany the syndrome, and a latent period of exposure before the onset of symptoms is typical. 

Reactions associated with treatment of narcotic addiction include difficulty sleeping, anxiety, nervousness, headache, low energy, irritability, increased energy, dizziness, abdominal cramps/pain, nausea, vomiting, loss of appetite, diarrhea, constipation, joint/muscle pain, delayed ejaculation, decreased potency, skin rash, chills, and increased thirst. 

Possible adverse reactions include headache anorexia nausea vomiting diarrhea palpitations tachycardia angina pectoris toxic reactions (particularly the LE cell syndrome) lacrimation conjunctivitis dizziness tremors psychotic reactions rash urticaria pruritus fever chills arthralgia eosinophilia constipation paralytic ileus lymphadenopathy splenomegaly nasal congestion flushing edema muscle cramps hypotension paradoxical pressor response dyspnea urination difficulty ... 

Ethacrynic acid Adverse reactions may include anorexia, pain, Gl bleeding, severe neutropenia, agranulocytosis, fever, chills, confusion, fatigue, malaise, sense of fullness in the ears, blurred vision, tinnitus, hearing loss (irreversible), rash. Furosemide Adverse reactions may include anorexia, cramping, constipation, blurred vision, hearing loss, restlessness, fever, anemia, purpura, thrombocytopenia, agranulocytosis, photosensitivity, urticaria, pruritus, thrombophlebitis, muscle spasm, weakness. 

Miscellaneous Edema (flurbiprofen, naproxen, meloxicam) thirst pyrexia (fever and chills) sweating breast changes gynecomastia muscle cramps facial edema menstrual disorders impotence vaginal bleeding influenza-like disease/symptoms (meloxicam). 

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