Mortality index

The minimum concentration causing irritant effect is, according to Muller, 01 mgm. per cu. m. A normal man cannot support a concentration greater than 0 4 mgm. per cu. m. for more than I minute. The mortality-index is 30,000 for 10 minutes exposure and 19,500 for 30 minutes exposure (Prentiss). 

Phosgene is said to be probably the most poisonous gas used in industry [1768] and an attempt has been made [1327] to derive a "mortality index" for phosgene based upon an analysis of data from explosions, releases of flammable gases, and from toxic releases of... 

Juniper decoction decreased glycemic level in normoglycemic rats at a dose of 250 mg/kg. The administration of the decoction to STZ diabetic rats resulted in a significant reduction in blood glucose levels and in the mortality index. It was suggested that this effect may be mediated by the peripheral action of juniper [150],... 

Mortality index An index based on the observed average ratio of casualties to the mass of material or energy released, as derived from the historical record. It is used to characterize the potential hazard of toxic material storage. 

Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. It is important for clinicians to understand AF, because it is associated with substantial morbidity and mortality and because many strategies for drug therapy are available. Drugs used to treat AF often have a narrow therapeutic index and a broad adverse effect profile. 

For instance, Wilkinson found that people are much more likely to feel trustful towards others in those US states in which income differences were smaller. Similarly, the hostility scores for 10 US cities found by R. B. Williams et al. (1995) were related to city mortality rates (r = —0.9), which have also been found to be related to the extent of income inequality in those cities. In addition, R. D. Putnam studied the functioning of regional governments in Italy, and notes that his index of civic community (measure of the strength... 

Kennedy, B. P., Kawachi, I. and Prothrow-Stith, D. (1996), Income distribution and mortality cross-sectional ecological study of the Robin Hood index in the United States , British MedicalJournal, 312, 1004-1007. 

Fattening poultry Fattening performance (important for fattener) weight gain, feed conversion, mortality, constitution (more leg problems and heart/ circulatory failure in lines with fast growing rate), productivity index (EBI European broiler index)... 

The World Health Organisation (WHO) defines obesity as a body mass index (BMI) greater than or equal to 30 kg/m, where BMI is calculated as weight in kilogram divided by the square of height in metre. Table 7.1 shows the WHO classification in full. BMI is a simple index of obesity and correlates well with total adiposity, morbidity and mortality from many diseases. ... 

Tricyclic antidepressants are cardiotoxic, inducing tachycardias and an increased tendency for ventricular arrhythmias with high doses. This dose dependent cardiotoxicity gives these agents a low therapeutic index. Overdoses are characterized by cardiac conduction disturbances, hyperpyrexia, hypertension, confusion, hallucinations, seizures and coma and there is a high mortality rate in suicide attempts. Depressed patients should therefore not be given more than one week supply of these drugs. 

Rahman P, Gladman DD, Urowitz MB, HaUett D, Tam LS. Early damage as measured by the SLICC/ACR damage index is a predictor of mortality in systemic lupus erythematosus. Lupus 2001 10 93-6. 

The compound is designated as positive (dysmorphogenic) or negative according to a calculated teratogenic index (TI>1.2 or TI < 1.0, respectively) determined from mortality and number of malformed larvae (see Note 1). 

NA not available, NC not concluded, ND not determined, Mort. mortality (embryotoxicity), Dysm. dysmorphogenesis, TJteratogenic index Therapeutic axis/targets showed for each of the 58 compounds. FETAX and in ivo data summarized by three main endpoints compound foimd embryo-... 

For candidates with a dysmorphogenic potential in FETAX, a teratogenic index (TI) was calculated where possible (Table 2). The reported mortality includes deaths during the larval period for FETAX and during the embryonic or fetal period (resorptions) for the rodent and rabbit. 

Measurements of arterial pressure, cardiac output, stroke work index, and pulmonary capillary wedge pressure are particularly useful in patients with acute myocardial infarction and acute heart failure. Such patients can be usefully characterized on the basis of three hemodynamic measurements arterial pressure, left ventricular filling pressure, and cardiac index. One such classification and therapies that have proved most effective are set forth in Table 13-4. When filling pressure is greater than 15 mm Hg and stroke work index is less than 20 g-m/m2, the mortality rate is high. Intermediate levels of these two variables imply a much better prognosis. 

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