MIDAS system

Dr. Schondelmeyers report to OTA is based on data from the IMS America, Inc. MIDAS system using the United States Drugstore and United States Hospital database. That database does not include sales made directly to mail-order distributors, health maintenance organizations, or Federal Government health purchasers (such as the U.S. Department of Veterans Affairs and the military.) In 1986, IMS America claimed the database reflected 98 percent of ethical pharmaceutical sales in the United States (368), but this share may be declining as mail-order pharmacies become more important. 

There are two perspectives on the MIDAS system architecture that describe the system to support these modes of analysis the functioned euchitecture and structural bases of the system. Each is discussed below. 

The MIDAS system has evolved over a period of 15 years of development (Corker and Smith 1992). The basic structure of the core system presented here is based on the work of Tyler et al. (1998). This architectural version of MIDAS has throughout its development been used to evrduate helicopter crew stations, short-haul civil tiltrotor emeigency handling operations, tmd the impact of MOPP flight gear on crew performance (Atendo et al. 1996, 1998 Shively et td. 1995). The spedfic development for analysis of air traffic management systems will be provided below. 

The user enters the system through the graphical user interface (GUI), which provides the main interaction between the designer and the MIDAS system. The user selects tunong four functions in the system ... 

Figure 22 Illustration of a Run-Time View of the MIDAS System with Cockpit, Pilot, and Copilot, and an Activity and Load Time as WeU as the Procedures and Goals That Are Currently Active in the System.

U.S. Army. 1997b. Munition Items Disposition Action System (MIDAS). Data provided to PMACWA in July by die Munition Items Disposition Action System (MIDAS) Team. Savanna, 111. U.S. Army Defense Ammunition Center (DAC). 

HPLC system Gold 128 (Beckman-Coulter) with autosampler (Midas, Spark) and EC detection CLC-100 (Chromsystems, Munich, Germany) is used. Sample results are analyzed by 32 Karat Software (Beckman Coulter). 

Spectral investigation of the interaction with MIDA and IDA shown that complex formation is accompanied with appearance of two new absorption bands in the spectrum of initial solution ([Am ]=1.25 lO M, [L]=riO M) [46], The maxima of these bands are near similar and equal to 504.9, 506.8 and 504.3, 506.3 nm for systems with IDA and MIDA, respectively, although, for MIDA these bands appear at slightly higher pH values. On the analysis of spectra the conclusion was made about the existence of 1 1 and 1 2 complexes with IDA and its derivatives. The data on complexation of Am, Cm and Cf are summarized in Table 3 [46]. 

SOURCE Adapted from data provided to PMACWA on the Munition Items Disposition Action System (MIDAS) by the MIDAS team in July 1997. 

A specialized method for similarity-based visualization of high-dimensional data is formed by self-organizing feature maps (SOM). The data items are arranged on a two-dimensional plane with the aid of neural networks, especially Kohonen nets. Similarity between data items is represented by spacial closeness, while large distances indicate major dissimilarities [968]. At the authors department, a system called MIDAS had already been developed which combines strategies for the creation of feature maps with the supervised generation of fuzzy-terms from the maps [967]. 

High-yielding Suzuki substitutions of halogen in halo-boronates are also possible using Al-methylimino-diacetic acid (MIDA) to form the protected boronate, which resists coupling under anhydrous conditions. This approach has been applied to aryl and heteroaryl (only thiophene and benzofuran, shown below) systems, and also for polyene synthesis. ... 

Olkkola KT, Backman JT, Neuvonen PJ. Mida lam should be avoided in patients receiving systemic antimycotics ketoconazole or itracona le. ClinPharmacol Ther ( 994) 55,481-5. 

MIDAS Case Study 1 Predicting Flight Crew Performance in the Advanced Air Traffic Management System... 

AN EXAMPLE OE A EIRST-PRINCIPLED APPROACH TO HUMAN/ SYSTEM PEREORMANCE MODELING THE MAN MACHINE INTEGRATED DESIGN SYSTEM (MIDAS)... 

MIDAS integrates the design process by using human performance models in the conceptual design phases of system development. Human-system integration and development enabled by the computational human performance models methodology are illustrated in Figure 20. 

Dynamic analysis capability The simulation system must produce a streeun of behavior in the form of dynamic timelines describing not only its state tmd structure, but also sequences of action over time and contingent responses of the human/system behavior. The system must support testable hypotheses. Designers must be able to analyze the events occurring in a simulation scenario and relate this performtmce to mtm-in-the-loop simulation data. In MIDAS, each action taken, decision made, and communication event is logged by the analysis system. 

Crew Station/equipment characteristics The crew station design module and library is a critical component in the MIDAS operation. Descriptions of discrete and continuous control operation of the equipment simulations are provided at several levels of functiontil deteiil. The system can provide discrete equipment operation in a stimulus-response (blackbox) format, a time-scripted/ event driven format, or a full discrete-space model of the transition among equipment states. Similarly, the simulated operator s knowledge of the system can be at the same varied levels of representation or can be systematically modified to simulate various states of misunderstanding the equipment function. 

Graphical Simulation Model MIDAS provides the user with a set of CAD development tools for both the design and modification of the simulation domain elements. The system also provides for the selection of a set of views or graphical simulation windows. These windows can provide various perspectives into the ongoing simulation, from that of a God s-eye view of the vehicles, environment and operators to views from the eyes of a particular human agent in the simulation. 

The MIDAS model of the controller was developed using the rules of current and free-flight operation. Estimates and measured times for controllers performance on these tasks was input into the task descriptions. Here the interest was in how stable the system was to emergency conditions under current and free-flight conditions. The control scenario was focused on the handoff between... 

Shively, R. J. et al. (1995), MIDAS Evaluation of AH-64D Longbow Crew Procedures in a Air-Ground Flight Segment MOPP versus Unencumbered, Sterling Federal Systems, NASA Ames Research Center. 

First-in-first-out (FIFO), 1521, 2157, 2167 First Man program, 1112 First price auctions, 274 First-principle models of human behavior, 2413-2414. See also Man-Machine Integrated Design and Analysis System (MIDAS)... 

Microsoft Excel, 2535 Microsoft Office for Windows, 2535 Microsoft Project 98, 1257 Microsoft Project 98 Plus, 1257 Microsoft Project 2000, 1261 Microsoft Project Central, 1261 Microsoldering, 431 Microsystem engineering, 365 MIDAS, see Man—Machine Integrated Design and Analysis System Middleware, 251, 661 MlDs, see Molded intercoimect devices MIES software, 1774, 1775, see Manufacturing information and execirtion systems software... 

---