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Major evasion

Bartee, E., et ah, Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J Virol, 2004, 78(3), 1109-20. [Pg.89]

If DMS concentrations at the surface of the ocean are presumed to be at steady state, production must balance loss. The fate of DMS is thought to be evasion across the sea surface into the marine atmospheric boundary layer. However, since rates of DMS production are unknown, it is impossible to compare production with flux to the atmosphere, which is relatively well constrained. An alternative sink for DMS in seawater is microbial consumption. The ability of bacteria to metabolize DMS in anaerobic environments is well documented (32-341. Data for aerobic metabolism of DMS are fewer (there are at present none for marine bacteria), but Sivela and Sundman (25) and de Bont et al. (25) have described non-marine aerobic bacteria which utilize DMS as their sole source of carbon. It is likely that bacterial turnover of DMS plays a major role in the DMS cycle in seawater. [Pg.158]

Many SCLC patients mount an antitumor immune response without signs of PNS [9, 167, 174]. Nevertheless, most SCLC patients do not have this immune response. Thus, the rarity of PNS cannot be attributed to infrequency of antigen expression. This discrepancy suggests that additional factors, perhaps related to tumor major histocompatibility complex (MHC) expression, contribute to the initiation of the PNS immune response. A study of Hu antigen and MHC class I expression in SCLC and neuroblastoma supports this theory. Seventeen of 20 tumors from Hu antibody positive patients expressed both proteins, but only 4 of 30 specimens from seronegative individuals expressed both proteins [171]. Altered expression and/or down-regulation of MHC molecules is a common immune-evasive strategy of tumor cells [175],... [Pg.165]

The main issue in hair testing is the avoidance of exogenous interpretive false positives, i.e., positives caused by external contamination of hair by drugs present in the environment, e.g., smoke, powder. This type of false positive is not the major issue for urinalysis where endogenous interpretive false positives are the main concern. But, the effective avoidance by urinalysis of exogenous false positives due to specimen contamination in the laboratory depends critically on the exclusion of drugusing personnel, and this can best be achieved by evasion-proof hair analysis. However, when such false positives occur, or when urinalysis labs are unable to guarantee that they have taken effective measures to exclude such contamination, then very little can be done to remedy the problem. For, in contrast to hair, the collection of a new urine specimen identical to the first one is not possible. [Pg.241]

Oceanic evasion is a major component of the mercury cycle. As described in greater detail in Section 9.04.5 below, there are a number of processes that may lead to evasion of elemental mercury from the ocean. Mason et al. (1994) found that evasion from the ocean had tripled in magnitude in concert with the increase in anthropogenic activities. Therefore, as with biomass burning, nearly two-thirds of the mercury currently evading from the ocean is anthropogenic. [Pg.4661]

The correct answer is that equilibrium moves to the product side because the amount of molecules are halved which leads to an evasion of the pressure . The majority of the students recognized this correctly and gave a correct explanation. Some of the students did not think that the pressure increase causes any change. They gave the following explanations ... [Pg.152]

In the event of a major incident, the consequences to people will probably be less serious than predicted by the release and incident outcome models described in Chapters 2 and 3 and the effect models in Chapter 4. This is not only because of uncertainties in modeling incident outcomes or modeling limitations that may lead to conservative assumptions and results but also because of topographical and physical obstruction factors, and because of evasive actions taken by people. Evasive actions can include evacuation, escape, sheltering, and heroic medical treatment. This chapter addresses the impact of evasive actions as mitigating factors to a CPQRA study. [Pg.275]


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