B lymphocyte cells

Adenosine deaminase deficiency is associated with an immunodeficiency disease in which both thymus-derived lymphocytes (T cells) and bone marrow-derived lymphocytes (B cells) are sparse and dysfunctional. Purine nucleoside phosphorylase deficiency is associated with a severe deficiency of T cells but apparently normal B cell function. Immune dysfunctions appear to result from accumulation of dGTP and dATP, which inhibit ribonucleotide reductase and thereby deplete cells of DNA precursors. 

Gutierrez M, Forster FI, McConnell SA, et al. The detection of CD2+, CD4+, CD8+, and WC1+ T lymphocytes, B cells and macrophages in fixed and paraffin embedded bovine tissue using a range of antigen recovery and signal amplification techniques. Vet. Immunol. Immunopathol. 1999 71 321-334. 

In addition, a distinction is made between cellular and humoral immune responses. The T lymphocytes (T cells) are responsible for cellular immunity. They are named after the thymus, in which the decisive steps in their differentiation take place. Depending on their function, another distinction is made between cytotoxic T cells (green) and helper T cells (blue). Humoral immunity is based on the activity of the B lymphocytes (B cells, light brown), which mature in the bone marrow. After activation by T cells, B cells are able to release soluble forms of their specific antigen receptors, known as antibodies (see p. 300), into the blood plasma. The immune system s memory is represented by memory cells. These are particularly long-lived cells that can arise from any of the lymphocyte types described. 

Immune responses have often been described in terms of humoral and cellular components. The humoral response involves the small circulating B lymphocytes (B cells), the antibodies (immunoglobulins), and proteins of the complement system. The cellular response is mediated by another group of small lymphocytes, the T lymphocytes (T cells). They resemble B cells in appearance but have quite different functions. However, newer knowledge has provided a somewhat different description of the body s defense... 

Cells Dendritic cells Phagocytic cells (neutrophils, monocytes, macrophages) Cells that release inflammatory mediators (basophils, mast cells, eosinophils) Natural killer (NK) cells Dendritic cells B lymphocytes (B cells) T lymphocytes (T cells) Other antigen-presenting cells, e.g., macrophages... 

Primary immunodeficiencies are uncommon, and may occur in 1 in 10,000 individuals (6). Many primary immunodeficiencies are hereditary and congenital, and first appear in infants and children. Primary immunodeficiencies are classified into four main groups (7) relating to the lymphocytes (B-cells, T-cells, or both), phagocytes, or the complement cascade (8). Primary deficiency diseases result from B-cell defects in 50% of cases, from T-cell defects in ca 10%, and from combined B- and T-cell defects in ca 20%. Phagocytic disorders account for 18% and complement defects occur in 2% of all cases. 

CD40L. Are important in inflammation and contributes significantly to the recruitment of inflammatory cells to damaged endothelium in vivo. Also present in lymphocytes B-cells, monocytes, macrophages, and endothelial cells. Regulate macrophage and smooth-muscle cells of the vascular wall. Induce cytokines secretion of endothelial cells... 

B lymphocytes, B cells or bone marrow-derived lymphocytes are formed in humans in the bone marrow by stem cells. On antigenic stimulation they develop into plasma cells and synthesize and secrete circulating antibodies. 

Lymphocytes are the lymphatic system s foot soldiers. These cells identify enemy particles and attempt to destroy them. Lymphocytes fall into two general categories T lymphocytes (T cells) and B lymphocytes (B cells). T cells form in the thymus (in the chest), and B cells form in the bone marrow of the long, thick bones of the thigh, arm, spine, or pelvis. While T cells primarily attack viral antigens, B cells attack bacterial antigens. Both T and B cells travel in lymph, through lymphatic vessels, and into lymph nodes. 

Rituximab CD20 Normal and malignant B-lymphocytes B-cell NHL Hypersensitivity and infusion-related reactions... 

B lymphocytes (B cells). Bone marrow-derived lymphocytes, expressing an antigen-receptor complex composed of membrane-bound - immunoglobulin (mlg) and associated molecular chains. B cell receptors interact with epitopes directly (no MHC restriction). Activated B lymphocytes produce antibody and are efficient antigen-presenting cells. They are the precursors of plasma cells. 

Cells Phagocytes (macrophages, Lymphocytes (B cells that... 

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