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Lithium in psychiatry

Schou, M. (1968). Lithium in psychiatry—A review. In D. H. Efron (Ed.), Pharmacology A review of progress 1957-1967 (Public Health Service Publication No. 1836). Washington, DC U.S. Government Printing Office. [Pg.515]

Lithium compounds are under investigation for a number of additional medical uses. Salzman has reviewed 21 additional potential uses of lithium in psychiatry that have been reported in the literature. Lithium has been shown to inhibit herpes, pox and adenoviruses in vitro and lithium succinate ointment is useful in treating herpes simplex infections. Interestingly,... [Pg.5466]

The use of lithium in psychiatry has varied historically. In the nineteenth century, lithium salts were employed in the treatment of anxiety, as well as gout and seizures. The importance of lithium s antimanic actions was indirectly discovered, in 1949, with observations that it produced a calming effect in animals. Human testing in agitated or manic patients followed, with encouraging results. However, lithium s use did not gain acceptance in American medicine until 1970, due to safety concerns... [Pg.159]

Lithium was introduced by Cade in 1949 for the treatment of acute mania (30). Unfortunately, the serious toxic effects of lithium were first recognized quite independently at about the same time, when lithium salts were used as a substitute for table salt in treatment of hypertension in the United States. Use of Westral, a lithium-containing salt substitute, caused a number of deaths (31,32). This unfortunate coincidence delayed the acceptance of lithium in psychiatry until Schou and others showed that lithium could safely be used in manic depressive disorder at rather lower doses than those used by Cade (33). The therapeutic index, however, is low. After its reluctant acceptance, the spectrum of therapeutic activity claimed for lithium then widened for a time, to include a broad range of psychiatric disorders, including schizophrenia. [Pg.52]

Lithium compounds are under investigation for a number of additional medical uses. Salzman has reviewed 21 additional potential uses of lithium in psychiatry that have been reported in the literature. Lithium has been shown to inhibit herpes, pox and adenoviruses in vitro and lithium succinate ointment is useful in treating herpes simplex infections. Interestingly, patients with dipolar disorder who are treated with oral lithium carbonate exhibit a reduction in the frequency of labial herpes recurrence. Lithium reduces brain damage in animal models of certain neurodegenerative diseases and has been shown to inhibit expression of apoptotic proteins, p53 and Bax, which leads to the possibility that it may be useful in treating neurodegenerative diseases. ... [Pg.5465]

Bowden CL, Calabrese JR, McElroy SL, et al (2000). A randomised, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Arch Gen Psychiatry 57, 481—9. [Pg.76]

Keck PE, Nabulsi AA, Taylor JL, et al (1996b). A pharmacoeconomic model of divalproex vs. lithium in the acute and prophylactic treatment of bipolar I disorder. J Clin Psychiatry 57> 213-22. [Pg.76]

Campbell, M., Adams, P.B., Small, A.M., Kafantaris, V., Silva, R.R., Shell, J., Perry, R., and Overall, J.E. (1995) Lithium in hospitalized aggressive children with conduct disorder a double-blind and placebo-controlled study. / Am Acad Child Adolesc Psychiatry 34 445-453. [published erratum appears in / Am Acad Child Adolesc Psychiatry 1995 34(5) 694]. ... [Pg.323]

Lenox, R.H. and Hahn, C.G. (2000) Overview of the mechanism of action of lithium in the brain fifty-year update. / Clm Psychiatry 61 5-15. [Pg.325]

M. (2000) A double-blind placebo-controlled study of lithium in hospitalized aggtessive children and adolescents with conduct dis-otdet. Arch Gen Psychiatry 57 649-654. [Pg.325]

Catlson, G.A., Rapport, M.D., Pataki, C., and Kelly, K.K. (1992a) Lithium in hospitalized children at 4 and 8 weeks affective, behavioral and cognitive effects. / Child Psychol Psychiatry 33 411— 425. [Pg.495]

Suppes, T, Baldessarini, R.J., and Faedda, G.L. (1991) Risk of recurrence following discontinuation of lithium in bipolar disorder. Arch Gen Psychiatry 48 1082-1088. [Pg.496]

Belelh D, Lan N, Gee KW Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex. Neurosci Biobehav Rev 14 315-322, 1990 Bellaire W, Demisch K, Stoll K-D Carbamazepine vs. lithium. Application in the prophylaxis of recurrent affective and schizoaffective psychoses. Muenchener Medizinische Wochenschrift 132 S82-S86, 1990 Belmaker RH Receptors, adenylate cyclase, depression, and lithium. Biol Psychiatry 16 333-350, 1981... [Pg.595]

Ebstein R, Belmaker R, Grunhaus L, et al Lithium inhibition of adrenaline-stimulated adenylate cyclase in humans. Nature 259 411-413, 1976 Ebstein RP, Hermoni M, Belmaker RH The effect of lithium on noradrenahne-in-duced cyclic AMP accumulation in rat brain inhibition after chronic treatment and absence of supersensitivity. J Pharmacol Exp Ther 213 161-167, 1980 Ebstein RP, Lerer B, Shlaufman M, et al The effect of repeated electroconvulsive shock treatment and chronic lithium feeding on the release of norepinephrine from rat cortical vesicular preparations. Cell Mol Neurobiol 3 191-201, 1983 Ebstein RP, Moscovich D, Zeevi S, et al Effect of lithium in vitro and after chronic treatment on human platelet adenylate cyclase activity prosreceptor modification or second messenger signal amplification. Psychiatry Res 21 221-228, 1987 Eccleston D, Cole AJ Calcium-channel blockade and depressive illness. Br J Psychiatry 156 889-891, 1990... [Pg.630]

Fieve RR, Platman SR, Plutchik RR The use of lithium in affective disorders, I acute endogenous depression. Am J Psychiatry 125 79-83, 1968 Fieve RR, Kumbaraci T, Dunner DL Lithium prophylaxis of depression in bipolar I, bipolar II, and unipolar patients. Am J Psychiatry 133 925-930, 1976 File SE Rapid development of tolerance to the sedative effects of lorazepam and triazolam in rats. Psychopharmacology 73 240-245, 1981... [Pg.635]

Freeman TW, Clothier JL, Pazzaglia P, et al A double-blind comparison of valproate and lithium in the treatment of acute mania. Am J Psychiatry 149 108-111,1992 Frenchman IB, Prince T Clinical experience with risperidone, haloperidol, and thioridazine for dementia-associated behavioral disturbances. Int Psychogeriatr 9 431-435, 1997... [Pg.639]

Garza-Trevino ES, Overall JE, Hollister LE Verapamil versus lithium in acute mania. Am J Psychiatry 149 121-122, 1992... [Pg.641]

Goodnick PJ, Gershon ES Lithium, in Handbook of Neurochemistry. Edited by Lajtha A. New York, Plenum, 1985, pp 103-149 Goodnick PJ, Meltzer HY Neurochemical changes during discontinuation of lithium prophylaxis, 1 increases in clonidine-induced hypotension. Biol Psychiatry 19 883-889, 1984... [Pg.646]

Goodwin FK, Roy-Byrne P Treatment of bipolar disorders, in Psychiatry Update The American Psychiatric Association Annual Review, Vol 6. Edited by fJales RE, Francis AJ. Washington, DC, American Psychiatric Press, 1987, p 89 Goodwin FK, Murphy DL, Bunney WE lithium-carbonate treatment in depression and mania a longitudinal double-blind study. Arch Gen Psychiatry 21 486-496, 1969... [Pg.647]

Jope RS Anti-bipolar therapy mechanism of action of lithium. Mol Psychiatry (in press ... [Pg.667]

Lerer B, Weiner RD, Belmaker RH Introduction, in ECT Basic Mechanisms. Edited by Lerer B, Weiner RD, Belmaker RH. London, John libbey, 1984, pp 1-4 Lerer B, Moore N, Meyendorff E, et al Carbamazepine versus lithium in mania a double-blind study. J Clin Psychiatry 48 89-93, 1987 Lerer B, Shapira B, Calev A, et al Antidepressant and cognitive effects of twice- versus three-times-weekly ECT. Am J Psychiatry 152 564-570, 1995 Lesch KP, Manji HK Signal-transducing G proteins and antidepressant drugs evidence for modulation of alpha subunit gene expression in rat brain. Biol Psychiatry 32 549-579, 1992... [Pg.683]

Mork A, Geisler A Mode of action of lithium on the catalytic unit of adenylate cyclase from rat brain. Pharmacol Toxicol 60 241-248, 1987 Mork A, Geisler A Effects of GTP on hormone-stimulated adenylate cyclase activity in cerebral cortex, striatum, and hippocampus from rats treated chronically with lithium. Biol Psychiatry 26 279-288, 1989a Mork A, Geisler A Effects of hthium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain. Eur J Pharmacol 168 347-354, 1989b... [Pg.702]

See other pages where Lithium in psychiatry is mentioned: [Pg.156]    [Pg.755]    [Pg.772]    [Pg.778]    [Pg.256]    [Pg.755]    [Pg.772]    [Pg.778]    [Pg.870]    [Pg.6900]    [Pg.6917]    [Pg.6923]    [Pg.290]    [Pg.28]    [Pg.277]    [Pg.279]    [Pg.281]    [Pg.283]    [Pg.156]    [Pg.755]    [Pg.772]    [Pg.778]    [Pg.256]    [Pg.755]    [Pg.772]    [Pg.778]    [Pg.870]    [Pg.6900]    [Pg.6917]    [Pg.6923]    [Pg.290]    [Pg.28]    [Pg.277]    [Pg.279]    [Pg.281]    [Pg.283]    [Pg.205]    [Pg.524]    [Pg.545]    [Pg.144]    [Pg.603]    [Pg.606]    [Pg.624]    [Pg.697]   
See also in sourсe #XX -- [ Pg.772 ]

See also in sourсe #XX -- [ Pg.772 ]

See also in sourсe #XX -- [ Pg.6 , Pg.772 ]



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