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Liquid chromatography-mass strategies

T. Reemstsma, Liquid chromatography-mass spectrometry and strategies for trace-level analysis of polar organic pollutants. J. Chromatogr.A, 1000 (2003) 477-501. [Pg.566]

Reemtsma, T. Liquid Chromatography-Mass Spectrometry and Strategies for Trace-Level Analysis of Polar Organic Pollutants. J. Chromatogr. A 2003, 1000, 477-501. [Pg.474]

G. J. Dear, R. S. Plumb, B. C. Sweatman, P. S. Parry, A. D. Roberts, J. C. Lindon, J. K. Nicholson, and I. M. Ismail, Use of directly coupled ion-exchange liquid chromatography-mass spectrometry and liquid chromatography-nuclear magnetic resonance spectroscopy as a strategy for polar metabolite identification, J. Chro-... [Pg.933]

Strategies for the Removal of Ionic and Non-Ionic Detergents From Protein and Peptide Mixtures For On- And Off-Line Liquid Chromatography Mass Spectrometry (LCMS)... [Pg.267]

Liquid chromatography-mass spectrometiy (LC-MS) based on atmospheric-pressure ionization (API) was demonstrated as early as 1974 (Ch. 3.2.1). However, it took until the late 1980 s before API was starting to be widely applied. Today, it can be considered by far the most important interfacing strategy in LC-MS. More than 99% of the LC-MS performed today is based on API interfacing. In this chapter, instrumentation for API interfacing is discussed. First, vacuum system for MS and LC-MS are briefly discussed. Subsequently, attention is paid to instrumental and practical aspects of electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and other interfacing approaches based on API. The emphasis in the discussion is on commercially available systems and modifications thereof. Ionization phenomena and mechanisms are dealt with in a separate chapter (Ch. 6). Laser-based ionization for LC-MS is briefly reviewed (Ch. 5.9). [Pg.105]

E. R. Verheij, Strategies for compatibility enhancement in liquid chromatography-mass spectrometry, Ph.D. thesis, Leiden University, 1993. [Pg.959]

Dear, G.J. Plumb, R.S. Sweatman, B.C. Parry, P.S. Roberts, A.D. Lindon, J.C. Nicholson, J.K. Ismail, I.M. Use of Directly Coupled Ion-exchange Liquid Chromatography-Mass Spectrometry and Liquid Chromatography-Nuclear Magnetic Resonance Spectroscopy as a Strategy for Polar Metabolite Identification, J. Chromatogr. B 748(1), 295-309 (2000). [Pg.284]

Dai DM, He JM, Sun RX, Zhang RP, Haji AA, Abliz Z. Nuclear magnetic resonance and liquid chromatography—mass spectrometry combined with an incompleted separation strategy for identif5nng the natural products in crude extract. Anal Chim Acta 2009 632 221-228. [Pg.610]

Liquid chromatography-mass spectrometry The initial attempts to couple LC with MS lacked important attributes for trace analysis sensitivity, robustness, and reliable quantitation. Moreover, the cost of the early LC-MS instruments was prohibitive for most laboratories. The revolutionary introduction of atmospheric pressure ionization (API) techniques, mainly electrospray (ESI) and atmospheric pressure chemical ionization (APCI), resulted in greater applicability of LC-MS and manufacture of more reliable, affordable, and user-friendly instruments. Thus, LC-MS is now becoming an indispensable part of the analytical strategy in many routine laboratories, enabling direct, selective, and sensitive multiclass, multiresidue analysis of more polar, low volatile, and/or thermolabile pesticides, such as carbamates, phenylureas, sulfonylureas, imidazoles, triazoles, imidazolinones, chlorophenoxy acids, and many others. [Pg.1504]

See also Chemometrics and Statistics Optimization Strategies. Chromatography Overview Principies. Derivatization of Analytes. Extraction Soivent Extraction Principies Solid-Phase Extraction. Forensic Sciences Systematic Drug Identification. Gas Chromatography Mass Spectrometry. Hormones Steroids. Liquid Chromatography Liquid Chromatography-Mass Spectrometry. Mass Spectrometry Atmospheric Pressure Ionization Techniques Forensic Applications. [Pg.1655]

High-performance liquid chromatography-mass spectrometry (HPLC-MS) is a powerful analytical technique widely used in recent years for the analysis of biomarkers and metabolites. Biomarker determination and quantification, whether metabolic or adducted biomolecules, are commonly used to evaluate exposure and support biomonitoring research, especially in the area of occupational exposure and health. Some of the common problems and strategies of HPLC-MS biomarker analysis involve matrix effects, the use of isotope-labeled internal standard compounds, and sample cleanup usually all of these factors must be evaluated within the development phase of an analysis procedure. Specific examples of biomarker analysis using HPLC-MS include acrylamide, aromatic compounds, and 1-bromopropane, and these examples are discussed in detail. [Pg.238]

STRATEGIES OF COUPLING PLANAR CHROMATOGRAPHY TO HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY... [Pg.174]

See other pages where Liquid chromatography-mass strategies is mentioned: [Pg.14]    [Pg.12]    [Pg.413]    [Pg.178]    [Pg.212]    [Pg.349]    [Pg.141]    [Pg.179]    [Pg.243]    [Pg.280]    [Pg.223]    [Pg.129]    [Pg.443]    [Pg.104]    [Pg.45]    [Pg.206]    [Pg.356]    [Pg.484]    [Pg.71]    [Pg.26]    [Pg.30]    [Pg.138]   
See also in sourсe #XX -- [ Pg.342 , Pg.345 ]



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