Latency time

The fact that the latency times were shorter than in methylene dichloride is readily explained because the polymerisation in 1,2-dichloroethane is faster, for the same working conditions [22]. The only substantial differences between the behaviour in the two solvents is the absence of the SD ions in runs conducted in 1,2-dichloroethane we were never able to detect a peak at 424 mp in these spectra. The nature of the ions, produced at the end of the polymerisations and absorbing at 395 mp, is still obscure. The rate of formation of ions after the polymerisation in 1,2-dichloroethane was very similar to that obtained for the equivalent experiments in methylene dichloride. 

Reference C. Discloses the dissolution of essentially pure compound C in an aqueous vehicle, and the administration to laboratory rats to determine its effect on the sleep latency time in rats. The compound decreased sleep latency (time to sleep onset) by 22 minutes. A separate reference is cited that shows that compounds like compound C can be readily prepared by synthetic methods common to one of ordinary skill in the art. This reference is cited to show that compound C is enabled. 

However, not all studies support the belief that urea is an effective penetration promoter.25,58-61 For instance, the latency time to induce erythema was not changed by three-weeks treatment with a moisturizer containing 5% urea62 or by pre-treatment of forearm skin with an aqueous solution of 10% urea.59 Moreover, urea (10%) had a minimal effect on the penetration of hydrocortisone through excised human and guinea pig skin.58 Hydrocortisone acetate was even retarded through hairless mouse skin with increasing concentrations of urea (up to 12%).25... 

Dependence on Ca2+ Sensing Latency Times, Ca2+ Channel Kinetic Parameters, and Channel Clustering... 

Note that in the limit q —> 0 of vanishing latency time, we obtain w(s) —> fo(s), as is to be expected. The only remaining problem then is to extract the waiting time distribution w(t) from its Laplace transform u>(s), a task complicated by the appearance of exponential factors in g< in the denominator in Eq. (22). 

The simulation data were extended for other multiple channel systems, up to ten channels these data are summarized in Figs. 11.4 to 11.6. The importance of channel clustering in case of large delay times is obvious from these figures, e.g. in the case of a 10 ms latency time, depolarizing pulses shorter than 20 ms practically do not induce exocytosis, even with clusters containing ten channels. 

We have shown here that a delay to the release of substances from secretory granules and vesicles, or a latency time that is inherent in the Ca2+-sensing machinery at the exocytosis site, convincingly shown to be present in at least some cell types,... 

A more complicated calculation of exocytosis probabilities requires more detailed knowledge about the distribution function of waiting times for the event that at least one channel is open during the latency time f/. Work in this direction is in... 

In synapses where the speed of exocytosis is usually most important, neutralization of the delay time in sensing the rising concentration of Ca2+ is achieved by arranging a large number of Ca2+ channels that open per individual secretory vesicle. Such an arrangement increases the probability of exocytosis practically to unity, even for short depolarizing pulses, i.e. comparable to the latency time q [14]. 

The rate of exocytosis from any type of cell is a very important factor and is therefore subject to strict regulation. This rate can be changed through the modification of different parameters of the exocytotic machinery. Analysis of pancreatic /J-cells shows that the latency time in the Ca2+ sensing system of the exocytotic machinery and the clustering of channels on the cell surface may be two convenient targets for adjusting the rate of the release of hormones or neurotransmitters from cells. 

Observed in some but not all studies Observed in some but not all studies Increased in some studies, particularly in individuals with high exposure and/or increased latency times... 

Group Latency Time near male odor Time near female odor First approach to F or M odor... 

Flumans exposed to 2NA during the production of this compound are at dramatically increased risk of urinary bladder cancer. According to one report all 15 workers involved with distilling the product fell victim to the disease. In other studies the relative risk of urinary bladder cancer ranged from 30 to 60 times higher than expected it not being uncommon that 50% of the exposed workforce was prevalent cases. As noted above the estimates of the so-called latency (time between first exposure and disease) period ranged for 16-30 - - years for 2NA-exposed workers. 

The shift of the post-processing to an HPC system, parallelization strategies, and the innovative data management mainly aimed at the reduction of total runtime. On the other hand, these approaches are not sufficient to fulfill the demand of short system response times needed for interactive exploration tasks. Because of the size of today s datasets, it is not possible to meet this criterion fully since the speed-up of an algorithm cannot be increased significantly. However, a fast representation of first temporary or approximate results leads to a considerable reduction of noticeable delays by simply decreasing the latency time of an algorithm. 

Hematologic cancer mortality (including lymphatic and hematopoietic cancers) Swedish capacitor manufacturing male workers employed 6 months versus Swedish national rates 142 1965-1982 1965-1978 (mean exposure 6.5 yrs) Observed versus expected 1 observed case The report identified one case of malignant lymphoma, expected number of cases was not reported, but the numbers of deaths from cancers was reported to correspond well with those expected. Median latency time=13 years. Gustavsson et al. 1986... 

At least 11 clinical trials with Valerian have been conducted most showed improvements in sleep quality and sleep latency (time taken to fall asleep). These effects were more noticeable in patients who were rated as poor sleepers than in healthy subjects. In one... 

Latency - Time from the first exposure of a chemical until the appearance of a toxic effect. 

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