Laboratorial Microsystem

Laboratorial microsystem Micro-total analysis system (pTAS) MTAS On-chip laboratory... 

Many traditional laboratory/off-line methods are now moving in the direction of in-process applications. Online GC had already been introduced in the 1950s. Using chip- and microsystem technology, xGC is now being introduced, which achieves analysis times of 30 seconds and is therefore suitable for quality control. SPME-p,GC is potentially useful for process analysis. 

Sample integrations similar to pharmaceutical approaches were already examined in 1997 [39]. Here, a chip-like microsystem was integrated into a laboratory automaton that was equipped with a miniaturized micro-titer plate. Microstructures were introduced later [40] for catalytic gas-phase reactions. The authors also demonstrated [41] the rapid screening of reaction conditions on a chip-like reactor for two immiscible liquids on a silicon wafer (Fig. 4.8). Process conditions, like residence time and temperature profile, were adjustable. A third reactant could be added to enable a two-step reaction as well as a heat transfer fluid which was used as a mean to quench the products. 

Reactor 9 [R 9] Laboratory Automaton Integrated Chip-like Microsystem... 

Here, a chip-like microsystem was integrated into a laboratory robot which was equipped with a miniaturized micro titer-plate. Micro structures were introduced later [52] for catalytic gas-phase reactions. The authors also demonstrated... 

These current and potential applications motivate the development of techniques for fabricating and manipulating objects with nanometer and micrometer feature sizes. This review gives a brief introduction to materials and techniques commonly used for microfabrication its focus is on those currently being explored in our laboratory. Our aim is to illustrate how non-traditional materials and methods for fabrication can yield simple, cost effective routes to microsystems, and how they can expand the capabilities of these systems. In a concluding section we provide brief descriptions of a number of other techniques for fabrication that, like those we are developing, may provide variable alternatives to photolithography. 

Microsystems Technology Laboratories, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Ibchnology, Cambridge, MA 02139... 

D. BONING, B. LEE, C. OJI, D. OUMA, T. PARK, T. SMITH, and T. TUGBAWA Massachusetts Institute of Technology, Microsystems Technology Laboratories,... 

Semiconductor and Microsystems Technology Laboratory Dresden University of Technology, Nothnitzer Str. 64, D-0II87 Dresden, Germany... 

The authors gratefully acknowledge Dr. Philip Manos (E. I. du Pont de Nemours Co.) for the preparation of 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (BDAF). The parallel plate capacitor micro test structure fabrication was performed in die Microsystems Technology Laboratories and the Microelectronics Laboratory of the Center for Materials Science and Engineering (MIT), which is supported in part by the National Science Foundation under Contract DMR-84-18718. 

Laboratory of Microsystems, Ecole Polytechnique FMerale de Lausanne, CH1015 Lausanne EPFL, Switzerland, martin. gijs epfl. ch... 

The nitration of aromatic compounds is a fundamental reaction [7] of utmost importance to the chemical industry. Many different regimens for this unit-process are known [8]. Nitrations have been described in microreactors [9-11] and during our own work with microreactors we have also gained experience with nitrations [12]. We have shown that it is possible to generate, in the laboratory, smaller amounts of chemicals using micro reactors, exemplified by the continuous nitration of 8.6 g of N-methoxycarbonyl-l,2,3,4-tetrahydro-isoquinoline over 6 full days. In an unlimited period of time one could produce unlimited amounts of chemicals with a single microsystem. Since this is unrealistic we are not... 

In order to characterize the adhesive properties of the blends we used mainly the instrumented probe test developed in our own laboratory [35]. While it is in principle identical to the type of probe tester presented by Zosel [36] and currently commercialized by Stable Microsystems under the name Texture Analyzer, our design has introduced some important differences, shown schematically in Fig. 22.7. We have added a 45° mirror and a video camera to be able to visualize the contact area through a transparent substrate, and a very stiff tripod to be able to adjust the parallelism between the adhesive film and the probe in order to maximize the contact area. Additionally, compared with the commercial instrument, the compliance of our probe tester is much lower, avoiding some of the interpretation problems associated with testing a stiff layer with a compliant... 

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