Isocyanic acid, 2- ethyl ester

SYNS ETHYL ISOCYANATE pOT) ISOCYANATOETHANE ISOCYANIC ACID, ETHYL ESTER... 

ISOCYANIC ACID, 3,3 -DIMETHYL-4,4 -BIPHENYLENE ESTER see DQSOOO ISOCYANIC ACID, ESTER with DI-o-TOLUENEMETHANE see MJN750 ISOCYANIC ACID, ETHYL ESTER see ELS500 ISOCYANIC ACID, 4-ELUOROBUTYL ESTER see FHC200... 

Synonyms Isocyanatoethane Isocyanic acid ethyl ester... 

Dichlorophenyl isocyanate Isocyanic acid, 3,3 -dimethoxy-4,4 -diphenylene ester. See Dianisidine diisocyanate Isocyanic acid, 3,3 -dimethyl-4,4 -biphenylene ester. See Bitoluene diisocyanate Isocyanic acid ethyl ester. See Ethyl isocyanate Isocyanic acid, hexamethylene ester. See Hexamethylene diisocyanate Isocyanic acid, hexamethylene ester, polymers. See Hexamethylene diisocyanate polymer Isocyanic acid, hexyl ester. See Hexyl isocyanate... 

Thus, 4-substituted 5-amino-3-benzylsulfanyl-l/7-pyrazole 65 derivatives (R = CN or COOEt) were treated with phosphoric acid ethyl ester chloride isocyanate in the presence of triethylamine under mild conditions (0-20 °C) for 3 h to give the ring-closed product 66 in medium to good yields (70% and 61%, respectively). 

DICHLOROPHOSPHORIC ACID, ETHYL ESTER (1498-51-7) May be combustible. Reacts with moisture in air, forming hydrogen chloride. Reacts with water, steam, forming hydrochloric acid. Incompatible with strong acids, strong oxidizers, nitrates. Aqueous solution incompatible with sulfuric acid, alkalis, ammonia, aliphatic amines, alkanolamines, alkylene oxides, amides, epichlorohydrin, organic anhydrides, isocyanates, vinyl acetate. Attacks some plastics, rubber, and coatings. Attacks metals in the presence of moisture. 

Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy] phenyl]-1-piperazinecarboxylic acid, ethyl ester. See Dichlorophenyl imidazoldioxolan Dichlorophenyl isocyanate. See 2,6-Dichlorophenyl isocyanate 2,3-Dichlorophenyl isocyanate 2,5-Dichlorophenyl isocyanate 3,4-Dichlorophenyl isocyanate 2,4-Dichlorophenyl isocyanate... 

Protection and Deprotection.—N-Protected a-amino-acids are readily esterified by methanol or ethanol in 60—80% yield after reaction with an enamine (e.g. from isobutyraldehyde and piperidine) and t-butyl isocyanate. Such amino-acids can also be esterified efficiently with alkyl halides under phase-transfer conditions with no racemization. Direct esterification of a-amino-acids with ethyl toluene-p-sulphonate in boiling ethanol gives a-amino-acid ethyl esters in 80—90% yield as the sulphonate salts. The protection of acid functions by formation of the 2-chloro-(or bromo-)ethyl esters has been discussed. These derivatives survive exposure to both moderately acidic and basic conditions and are removable by conversion into the iodoethyl analogues followed by zinc reduction. Alternatively, they may be converted into hydrophilic ammonium or phosphonium salts which exhibit enhanced acid stability but which are cleaved by very dilute base. Yet another method for the removal of such groups using supernucleophilic Co phthalocyanin anions has been reviewed. Further routes to 2,2,2-trichloroethyl esters have been described, one of which employs an activated ester intermediate and is suited to acid-labile substrates. 

Isocyanic acid, 2-(chIoroformyl)ethyl ester (8) Propanoyl chloride, 3-isocyanato- (9) (3729-19-9)... 

Carbimazole Carbimazole, the ethyl ester of 3-methyl-2-thioimidazolin-l-carboxylic acid (25.2.7), is synthesized by a simultaneons reaction of ethylenacetal of bromoacetaldehyde with methylamine and potassium isocyanate, forming 3-methyl-2-imidazolthione (25.2.6), which is further acylated at the nitrogen atom by ethyl chloroformiate, giving the desired product (25.2.7) [17-19]. 

Alkoxythiocarbonyl isothiocyanates (172 X = S) are also useful 47t components and with imines at room temperature furnish 6-alkoxy-2//-l,3,5-thiadiazine-4(3//)-thiones (173) albeit in variable yields <83CB2044>. In a similar manner ethoxythiocarbonyl isocyanate (172 R = Et, X = O) and benzylideneaniline produce 2,3-diphenyl-6-ethoxy-2/f-l,3,5-thiadiazin-4(3//)-one (174) <82CB1252>. In warm toluene the ethoxythiocarbonyl isocyanate dimerizes to give the 0-ethyl ester (175) of 6-ethoxy-3,4-dihydro-2,4-dioxo-2//-l,3,5-thiadiazine-3-thiocarboxylic acid (Scheme 24). 

Benzoylbenzoates, 347 Benzoyl chloride, 171 Benzoyl cyanide, 35 Benzoylhydrazine, 36 At-Benzoylimidazolc, 35 Benzoyl isocyanate, 35 Bcnzoyl-L-leucine, 193 Benzoyl-L-leucylglycine ethyl ester, 193 Benzoyloxylation, 160 N-Benzoylperoxycarbamic acid, 35-36 N-Benzoyl-N -triflylhydrazine, 36 Benzpyrene-l-ol, 316... 

Carbamyl chloride, N,N-dimethyl-. See Dimethylcarbamyl chloride Carbamyl hydroxamate. See Hydroxyurea Carbanil. See Phenyl isocyanate Carbanilaldehyde. See N-Phenylformamide Carbanilic acid, m-chloro-, 1-methyl-2-propynyl ester. See Chlorbufam d-(-)-Carbanilic acid (1-ethylcarbamoyl) ethyl ester. See Carbetamide Carbanilic acid, m-hydroxy-, methyl ester, m-methyl carbanilate. See Phenmedipham Carbanilic acid isopropyl ester. See Propham Carbanilide. See N,N -Diphenylurea Carbani Ii de, 4,4 -dichIoro-3-(trifluoromethyl)-. See Cloflucarban... 

CAS 622-58-2 EINECS/ELINCS 210-743-4 Synonyms Benzene, 1-isocyanato-4-methyl- 1-lsocyanato-4-methylbenzene 4-Isocyanatotoluene p-lsocyanatotoluene Isocyanic acid, p-tolyl ester 4-Methylphenyl isocyanate p-M ethyl phenyl isocyanate TMI p-TMl 4-Toluene isocyanate p-Toluene isocyanate 4-Tolyl isocyanate Classification Isocyanic acid ester Empirical CsHyNO... 

Blocked isocyanates permit making coatings that are stable at ambient temperature when baked, the monofunctional blocking agent is volatilized and the coreactant is cross-linked. An extensive review of blocked isocyanates, their reactions, and uses is available (127). The blocking agents most widely used are phenols, oximes, alcohols, e-caprolactam (hexahydro-2ff-azepin-2-one) [105-60-2], 3,5-dimethylpyrazole, 1,2,4-triazole, and diethyl malonate (propanedioic acid diethyl ester) [105-53-3]. A variety of catalysts are used DBTDL is most widely used but many other catalysts have also been used. Bismuth tris(2-ethyl hexanoate) has been particularly recommended (128). In electrodeposition primers, DBTDL has insufficient hydrolytic stability, and tributyltin oxide is an example of an alternate catalyst (129). Cyclic amidines, such as l,5-diazabicyclo[4.3.0]non-5-ene, are reported to be superior catalysts for use with uretdione cross-linkers in powder coatings (130). 

To achieve biodegradability and nontoxicity, there has been intensive research on replacing common isocyanates with amino acid diisocyanates in the development of waterborne PUs [69]. L-Lysine diisocyanate and L-lysine ethyl ester diisocyanate have gained attention because lysine is nontoxic, less prone to inflammation, and easy to connect with bioactive molecules. Lysine ethyl ester diisocyanate was prepared with an improved method that avoids the use of gaseous phosgene, elevated temperature, and strongly acidic conditions as described by Nowick et al. [70]. L-Lysine diisocyanate and PCL diol were used as main components to prepare nontoxic and... 

The isocyanate from 2-amino-2-trijluoromethyl succinic acid 1-ethyl ester 4-methyl ester 457 was prepared in high yield using diphosgene in toluene [316]. 

N-Substituted esters of carbamic acid (carbamic acid is the mono-amide of carbonic acid) are compounds containing the -NHCOOR group, and are named carbamates or urethanes. Urethane (or urethan) is also used as a name for ethyl carbamate 515, NH2COOEt (a compound which has been shown to act as a carcinogen in some animals), and sometimes even for the whole class of carbamate esters. It is formed by reaction of ethanol with isocyanic acid 516 or urea 517. Since "urethane nomenclature may be confusing there is litde justification in its continued use. 

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