3.5- dichlorophenyl isocyanate

Dicliloroethane, 52 Dichloroethyl ether, 52 Dichloromethane, 52 Dichloromethyl ether, 52 Dichloromethylphenylsilane, 52 Dichloromonofluoromethane, 52 2-(2,4-Dichlorophenoxy) propionic acid, 52 Dichlorophenyl isocyanates, 53... 

C7H3C12F3 2,4-DICHLOROBENZOTRIFLUORIDE 3,4-DICHLOROPHENYL ISOCYANATE p-CHLOROBENZOTRIFLUORIDE m-CHLOROBENZOYL CHLORIDE 3-NITROBENZOTRI FLUORIDE BENZOYL CHLORIDE o-CHLOROBENZOIC ACID BENZOTRI CHLORIDE BENZOTRI FLUORIDE BENZONITRILE PHENYL ISOCYANATE 2,4,6-TRINITROTOLUENE... 

Chemical/Physical. Diuron decomposes at 180 to 190 °C releasing dimethylamine and 3,4-dichlorophenyl isocyanate. Dimethylamine and 3,4-dichloroaniline are produced when hydrolyzed or when acids or bases are added at elevated temperatures (Sittig, 1985). The hydrolysis half-life of diuron in a 0.5 N NaOH solution at 20 °C is 150 d (El-Dib and Aly, 1976). When diuron was pyrolyzed in a helium atmosphere between 400 and 1,000 °C, the following products were identified dimethylamine, chlorobenzene, 1,2-dichlorobenzene, benzonitrile, a trichlorobenzene, aniline, 4-chloroaniline, 3,4-dichlorophenyl isocyanate, bis(l,3-(3,4-dichlorophenyl)urea), 3,4-dichloroaniline, and monuron [3-(4-chlorophenyl)-l,l-dimethylurea] (Gomez et al., 1982). Products reported from the combustion of diuron at 900 °C include carbon monoxide, carbon dioxide, chlorine, nitrogen oxides, and HCl (Kennedy et al., 1972a). 

Dichlorophenyl isocyanate, see Diuron l-(3,4-Dichlorophenyl)-3-methoxymethylurea, see Methazole... 

Chlorotrifluoromethyl aniline (no. 73.) was found in the sediment samples. This compound is used as a reactant with chloro-aniline (no. 72) in the preparation of 4,4 -dichloro-3-(trifluoromethyl)-carbanilide, a disinfectant. Two other related compounds also found in some of the sediments were chlorophenyl isocyanate (no. 74) and chloro(-trifluoromethyl)phenyl isocyanate (no. 75). This suggests that some of the 4,4 -dichloro-3-(trifluoromethyl)-carbanilide may, in fact, exist in the sediment extracts but is decomposed in the injection port of the gas chromatograph, since it is very doubtful that the easily hydrolyzable isocyanates exist as such in the sediments. To strengthen this hypothesis some 3,4,4 -trichlorocarbanilide [none of the 4,4 -dichloro-3-(trifluorome-thyl)-carbanilide was available] was analyzed by GCMS. The injection port temperature was 300°C. As expected, none of the parent compound eluted from the column. However, mass spectra were obtained for chlorophenyl isocyanate, dichlorophenyl isocyanate, chloroaniline, and dichloroaniline. The presence of the carbanilides themselves (no. 76, 77, 78) was confirmed with the help of HPLC and mass spectral identification. 

To a solution of 298 gm (8 equivalents) of hydrazine in ether is slowly added with stirring and cooIing215 gm (1.15 moles) of 3,4-dichlorophenyl isocyanate in 2 liters of ether while keeping the temperature at 20°C. After the addition the ether layer is decanted from the oily layer. On dilution of the oily layer with water is obtained 237.5 gm of a solid. Recrystallization from ethanol and filtration to remove the insoluble l,6-bis(3,4-dichlorophenyl)biurea afford 108.6 gm of a solid, m.p. 175°-177°C. An additional recrystallization from 700 ml of ethyl acetate affords 77.3 gm (30%), m.p. 173°175°C, ir 3.00, 3.10 p. (NH), 5.90 jji (C=0). 

The quaternization method is also highlighted by the short asymmetric synthesis of cell adhesion molecule BIRT-377 (Scheme 5.24), which is a potent inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1) [16]. Thus, asymmetricp-bromobenzylation of the alanine derivative 42 (R1 = Me) with (S)-18 under similar phase-transfer conditions as described above gave rise to p-bromobenzylalanine ester 10 in 97% ee (83% yield). A similar asymmetric p-bromobenzylation of alanine ethyl ester 42 (R1 = Me, R= Et) gave the amino ester 47 (R= Et) in 90% ee (86% yield). The amino ester 47 (R = t-Bu or Et) was treated with 3,5-dichlorophenyl isocyanate in the presence of sodium carbonate in dimethylsulfoxide (DMSO) to furnish the hydantoin 48 in 86%... 

Pipeline seal exposed to dichlorophenyl isocyanate at elevated temperatures... 

C6H15NO 4-amino-4-methyl-2-pentanol 4404-98-2 21.64 0.8872 2 9530 C7H3CI2NO 2,6-dichlorophenyl isocyanate 39920-37-1 25.00 1.4000 2... 

C7H3CI2NO 3,4-dichlorophenyl isocyanate 102-36-3 1.150E+10 80.320 11843 C7H140 2,4-dimethyl-3-pentanone 565-80-0 1.122E+10 79.940... 

Dichlorophenyl isocyanate STPC Chuo Kaseihin Carbolabs... 

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