Toluene di-isocyanate

Thermo-oxidative breakdown of the cross-linked polymer derived from toluene-2,4-di-isocyanate, methylene bis(4-amino-3-chloroph0iyl), and a hydroxy-terminated polybutadiene occurred, however, by a radical mechanism... 

Direct addition pol3mieri2ation of 2-amino-2-deoxy-D-glucose and a diisocyanate (4,4 -methylene-diphenyl-l, 1 -di-isocyanate, phenyl-1,4-di-isocyanate, toluene-2,4-di-isocyanate, or butyl-1,4-di-isocyanate) yields a linear sugar-containing poly(urea-urethane) (5) having good solubility in organic solvents, unlike chitin or chitosan. ... 

Toluene 2,4-Diisocyanate. 2,4-Di isocyan atotolu -ene 2.4-tolylene diisocyanate TDI Nacconate 100, CjH -NjOj mol wt 174.15. C 62.07%, H 3.47%, N 16.09%, O 18.37%. Usually prepd from toluene-2,4-diamine and phosgene. Review Astle, Industrial Organic Nitrogen Compounds (New York, 1961) pp 284-313 Faith, Keyes Clark s Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley -lntersdenee, New York, 4th ed., 1975) pp 831-835. 

Aromatic diisocyanates such as toluene 2,4-diisocy-anate (TDI) and methylene di-p-phenylene isocyanate (MDl) are usually used. Aliphatic diisocyanate such as hexanediisocyanate (HDI), although it has the advantage that the TPU synthesized from it is softer and not prone to turning yellow, is seldom used due to its high cost. 

Isoouanates. Various isocyanates are employed in the polymer industry. These compounds are powerful irritants and they are highly toxic. Of particular interest are methylene-di-paraphenylene isocyanate (MDI) and toluene-2,4-diisocyanate (TDI). Various alkyl isocyanates (e.g., methyl, ethyl, propyl, butyl, and cyclohexyl) derivatives may also be of current interest with respect to potential occupational health hazards. Simultaneous analysis of MDI and TDI by HPLC has been accomplished by a modification of the method of Dunlap et al. (28). Air samples are collected in impingers containing p-nitrobenzyl-n-... 

The reaction of cotton cellulose with phenyl isocyanate, to give a cellulose phenylurethan, has been investigated further. The extent of the reaction depends on the ability of the solvent to swell the cellulose, methyl sulfoxide being the best medium, followed by i r,f T-dimethylformamide and P3Tidine. The reaction is catalyzed by the addition of di-w-butyltin diacetate, but toluene 2,4-diisocyanate and 1,2,4,5-tetramethylbenzene diisocyanate do not show high reactivity. A survey of the relative behavior of chitin and cellulose toward esterification under comparable conditions, mainly to give arylsulfonate esters, concluded that, of the two, chitin is the less reactive. 

Like most other isocyanates, IPDI exhibits moderate toxicity via inhalation. The acnte toxic symptoms are somewhat similar to those of toluene-2,4- diisocyanate and di-phenylmethane-4,4 -diisocyanate. Thns the toxicity of such types is a characteristic of the —N=C=0 functional gronp and to a great extent is independent of the natme of the ring. 

Toluenediisocyanate. See Toluene-2,4-diisocyanate Tol uene-2,6-di isocyanate CAS 91-08-7 EINECS/ELINCS 202-039-0 UN 2078 2207 (DOT)... 

C9H6N202 TOLUENE DI ISOCYANATE -5.078 5.7582E-01 2.9402E-04 -9.0683E-07 4.3055E-10 298 1000... 

The monomeric imidazole-blocked 1,4-phenyIenediisocyanates with n-alkoxymethyl substituents were prepared from 2,5-bis(n-alkoxymethyI) terephthalic acids by chlorination with oxalyl chloride in DM Ac at 0 C[19 - 21] followed by reaction with aqueous NaN3 as shown in Scheme 1. The isolated azido products were rearranged to isocyanates in the presence of excess imidazole at 85 °C in toluene. On cooling were precipitated the DIS-IBDIs, which were thoroughly purified by recrystallization from acetone. The substituted terephthalic acids were prepared by basic hydroysis of 2,5-bis(n-alkoxymethyl)-terephthalonitriles[17 - 18]. 

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