Inductively coupled plasma ion sourc

Glow discharge source (GDMS) Laser ion source (LIMS) Secondary ion source (SIMS) Sputtered neutral source (SNMS) Thermal ionization source (TIMS) Inductively coupled plasma ion source (ICP-MS)... 

The ion source is an essential component of all mass spectrometers where the ionization of a gaseous, liquid or solid sample takes place. In inorganic mass spectrometry, several ion sources, based on different evaporation and ionization processes, such as spark ion source, glow discharge ion source, laser ion source (non-resonant and resonant), secondary ion source, sputtered neutral ion source and inductively coupled plasma ion source, have been employed for a multitude of quite different application fields (see Chapter 9). 

Laser Ablation Coupled to an Inductively Coupled Plasma Ion Source... 

Recently, Hieftje et al.15-16 equipped a small double-focusing mass spectrograph built in house with Mattauch-Herzog geometry with several ion sources (such as glow discharge, an inductively coupled plasma ion source or a microwave plasma torch) and a novel array detector for simultaneous ion detection. 

Fourier transform ICR mass spectrometers together with any type of ion source, such as nanoESI, MALDI (or also an inductively coupled plasma ion source) permit mass spectrometric measurements to be performed at ultrahigh mass resolution (R = m/hm = 105—106) with a very low detection limit and the highest possible mass accuracy (Am = 10 3—10 4 Da). In addition, a high mass range is possible and FTICR-MS can be applied for MS/MS experiments.48 A comparison of different separation systems used in inorganic mass spectrometry is presented in Table 3.1. 

One of the more recent branches of atomic spectrometry, although perhaps the most exciting one, is atomic mass spectrometry, which has had a very important impact on science and technology. At present, atomic mass spectrometry is ordinarily performed using inductively coupled plasma ion sources and either a quadrupole or a scanning sector-field mass spectrometer as an analyser. The remarkable attributes of such a combination, being an indispensable tool for elemental analysis, include ... 

Milgram, K. E. Abatement of spectral interferences in elemental mass spectrometry design and construction of inductively coupled plasma ion sources for Fourier Transform ion cyclotron resonance instrumentation, Ph. D. Thesis, University of Florida, 1997, Diss. Abstr. Int., B 1998, 59(2), 639. 

The inductively coupled plasma ion source was developed to accomplish exactly the opposite of the two soft ionization methods just described. Molecules are reduced to their atomic (i.e. elemental) components through the application of intense energy. Masses corresponding to elements of interest (e.g. 30.974 for phosphorus) are then specifically monitored. 

Guilhaus M (2000) Essential elements of time-of-flight mass spectrometry in combination with the inductively coupled plasma ion source. Spectrochimica Acta 55 1511-1525. 

ICP-MS is advantageous over RIMS and AMS due to fast and relatively inexpensive multielement determination, precise and accurate isotopic analysis at the trace, and ultratrace concentration levels in any material. Another advantage of ICP-MS compared to other atomic mass spectrometric techniques is the simple sample preparation and introduction of aqueous solutions into the normal-pressure inductively coupled plasma ion source. 

Improvements in instrumentation with inductively coupled plasma ion sources, especially with the sensitivity available with plasma-source double-focusing magnetic sector inductively coupled plasma mass spectrometer (MS-ICP-MS) instrumentation, have enabled similar accuracy as that which can be obtained using... 

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