Project Implementation

Stamm, J. et al.. 1996, Safety Monitor Implementation Project at Wolf Creek, Callaway, and Comanche Peak Stations, PSA 96, Park City, UT, p 12-19, Sept. 29 - Oct. 3. 

We recommend that the implementation project go ahead with a target completion date 24 months from now... 

This project was slightly unusual, in that the success and ROI criteria were investigated and developed ahead of the rest of the project. This led to a project that had clear goals and milestones in terms of usability and performance, set out ahead of any review of available solutions. In addition, the project had measurable criteria for the impact that the system was having on the efficiency of the drug discovery process. These criteria were then also used to establish go/no-go criteria for the implementation project. 

Registration, Evaluation and Authorisation of CHemicals REACH Implementation Project... 

The Ministry is supporting the establishment of pilot implementation projects in Austria, where six implementation projects covering a wide range of applications and technologies have been or are being implemented. 

Once the alternatives have been evaluated, management has to chose the preferred network design and approve an implementation project. Alternatively, the planning process has to be repeated to develop further alternatives. 

Key elements that must be successfully executed on computer implementation projects... 

User requirements specification—The URS is an overview of the system functionally from the perspective of the end users needs. This document is often the first document generated to kick off a new CRS design and implementation project. It can be drafted early on by a... 

Secure Approval for Implementations Begin Implementation Projects Keep People Involved... 

EU (2005) Work Package 1. Development of the concept of exposure scenarios. General framework of exposure scenarios. Scoping study for technical guidance document on preparing the chemical safety report under REACH, final report. European Union, European Chemicals Bureau (REACH Implementation Project 3.2-1A Lot 1 Commission Service Contract No. 22551-2004-12 FISC ISP BE ... 

Regulators use DNEL and PNEC to set health or environmental standards, but usually in conjunction only with exposure levels. For non-threshold effects, when a DNEL or PNEC may not apply, probabilities of the incidence of an effect for an individual within a population are used to set regulatory limits on exposure. Recent regulatory discussions within the REACH Implementation Projects... 

RRS = Risk-reduction strategy TGD = Technical guidance document [28] RIPs = REACH implementation projects... 

REACH-IT RIP RRS SAICM REACH-Information Technology REACH implementation project(s) Risk reduction strategy(ies) UNEP Strategic Approach to International Chemicals Management... 

Where a LIMS implementation project is split over a number of different locations (e.g., different laboratories or different sites) but is designed to provide an integrated solution, it may be appropriate to produce individual Validation Plans and associated documentation for each of the LIMS location. Where an installation is implemented and supported on a company corporate basis, it may be more appropriate for the VMP and the resulting validation documentation for the core LIMS to be managed from a central location. In such cases Validation Plans and associated validation documentation supporting the local implementation should be maintained on site. 

To conclude, the implementation project Validation Report is prepared in response to the Validation Plan issued at the beginning of the project. It snmmarizes what went according to plan, and explains what did not go to plan. Amendments to the plan must be justified. Some issues may still be outstanding, in which case forward andit trails to corrective actions must be made. The Validation Report mnst demonstrate that the MRP II implementation is fit for purpose and can be used to support drug manufacturing. Dne to the large nnmber of documents often associated with these projects a library index or ronte map may also be nseful to include either in the Validation Report or, more commonly, to reference in the report as a separate document. 

There are often many thousands of project documents for MRP II systems. They should all be subject to document (life-cycle) management including following approval processes, indexing, and archiving. Document management must cover the implementation project, operation, and maintenance of the system. 

A mid-1990s survey presented at a LIMS conference concluded that 50% of all LIMS implementation projects failed. No explanation was attempted, and the conclusion most people drew was that the LIMS systems were not good enough. The author gives two reasons, both of which seemed to be common in the failed projects ... 

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